Stevens MF - Search Results

1

Antitumour benzothiazoles. Part 32: DNA adducts and double strand breaks correlate with activity; synthesis of 5F203 hydrogels for local delivery.

Stone EL, Citossi F, Singh R, Kaur B, Gaskell M, Farmer PB, Monks A, Hose C, Stevens MF, Leong CO, Stocks M, Kellam B, Marlow M, Bradshaw TD. Stone EL, et al. Among authors: stevens mf. Bioorg Med Chem. 2015 Nov 1;23(21):6891-9. doi: 10.1016/j.bmc.2015.09.052. Epub 2015 Oct 3. Bioorg Med Chem. 2015. PMID: 26474663

2

Antitumour 2-(4-aminophenyl)benzothiazoles generate DNA adducts in sensitive tumour cells in vitro and in vivo.

Leong CO, Gaskell M, Martin EA, Heydon RT, Farmer PB, Bibby MC, Cooper PA, Double JA, Bradshaw TD, Stevens MF. Leong CO, et al. Among authors: stevens mf. Br J Cancer. 2003 Feb 10;88(3):470-7. doi: 10.1038/sj.bjc.6600719. Br J Cancer. 2003. PMID: 12569393 Free PMC article.

3

Antitumour benzothiazoles. Part 20: 3'-cyano and 3'-alkynyl-substituted 2-(4'-aminophenyl)benzothiazoles as new potent and selective analogues.

Hutchinson I, Bradshaw TD, Matthews CS, Stevens MF, Westwell AD. Hutchinson I, et al. Among authors: stevens mf. Bioorg Med Chem Lett. 2003 Feb 10;13(3):471-4. doi: 10.1016/s0960-894x(02)00930-7. Bioorg Med Chem Lett. 2003. PMID: 12565953

4

Antitumor benzothiazoles. 26.(1) 2-(3,4-dimethoxyphenyl)-5-fluorobenzothiazole (GW 610, NSC 721648), a simple fluorinated 2-arylbenzothiazole, shows potent and selective inhibitory activity against lung, colon, and breast cancer cell lines.

Mortimer CG, Wells G, Crochard JP, Stone EL, Bradshaw TD, Stevens MF, Westwell AD. Mortimer CG, et al. Among authors: stevens mf. J Med Chem. 2006 Jan 12;49(1):179-85. doi: 10.1021/jm050942k. J Med Chem. 2006. PMID: 16392802

5

Structural studies on bioactive compounds. 40.(1) Synthesis and biological properties of fluoro-, methoxyl-, and amino-substituted 3-phenyl-4H-1-benzopyran-4-ones and a comparison of their antitumor activities with the activities of related 2-phenylbenzothiazoles.

Vasselin DA, Westwell AD, Matthews CS, Bradshaw TD, Stevens MF. Vasselin DA, et al. Among authors: stevens mf. J Med Chem. 2006 Jun 29;49(13):3973-81. doi: 10.1021/jm060359j. J Med Chem. 2006. PMID: 16789754

6

Antitumour properties of fluorinated benzothiazole-substituted hydroxycyclohexa-2,5-dienones ('quinols').

Lion CJ, Matthews CS, Wells G, Bradshaw TD, Stevens MF, Westwell AD. Lion CJ, et al. Among authors: stevens mf. Bioorg Med Chem Lett. 2006 Oct 1;16(19):5005-8. doi: 10.1016/j.bmcl.2006.07.072. Bioorg Med Chem Lett. 2006. PMID: 16908135

7

Antitumor benzothiazoles. 3. Synthesis of 2-(4-aminophenyl)benzothiazoles and evaluation of their activities against breast cancer cell lines in vitro and in vivo.

Shi DF, Bradshaw TD, Wrigley S, McCall CJ, Lelieveld P, Fichtner I, Stevens MF. Shi DF, et al. Among authors: stevens mf. J Med Chem. 1996 Aug 16;39(17):3375-84. doi: 10.1021/jm9600959. J Med Chem. 1996. PMID: 8765521

8

Antitumour benzothiazoles. Part 10: the synthesis and antitumour activity of benzothiazole substituted quinol derivatives.

Wells G, Bradshaw TD, Diana P, Seaton A, Shi DF, Westwell AD, Stevens MF. Wells G, et al. Among authors: stevens mf. Bioorg Med Chem Lett. 2000 Mar 6;10(5):513-5. doi: 10.1016/s0960-894x(00)00027-5. Bioorg Med Chem Lett. 2000. PMID: 10743960

9

The discovery of the potent and selective antitumour agent 2-(4-amino-3-methylphenyl)benzothiazole (DF 203) and related compounds.

Bradshaw TD, Stevens MF, Westwell AD. Bradshaw TD, et al. Among authors: stevens mf. Curr Med Chem. 2001 Feb;8(2):203-10. doi: 10.2174/0929867013373714. Curr Med Chem. 2001. PMID: 11172675 Review.

10

Antitumor benzothiazoles. 14. Synthesis and in vitro biological properties of fluorinated 2-(4-aminophenyl)benzothiazoles.

Hutchinson I, Chua MS, Browne HL, Trapani V, Bradshaw TD, Westwell AD, Stevens MF. Hutchinson I, et al. Among authors: stevens mf. J Med Chem. 2001 Apr 26;44(9):1446-55. doi: 10.1021/jm001104n. J Med Chem. 2001. PMID: 11311068

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