Schurdak M - Search Results

1

A metric and workflow for quality control in the analysis of heterogeneity in phenotypic profiles and screens.

Gough A, Shun TY, Lansing Taylor D, Schurdak M. Gough A, et al. Among authors: schurdak m. Methods. 2016 Mar 1;96:12-26. doi: 10.1016/j.ymeth.2015.10.007. Epub 2015 Nov 4. Methods. 2016. PMID: 26476369 Free PMC article.

2

Identifying and quantifying heterogeneity in high content analysis: application of heterogeneity indices to drug discovery.

Gough AH, Chen N, Shun TY, Lezon TR, Boltz RC, Reese CE, Wagner J, Vernetti LA, Grandis JR, Lee AV, Stern AM, Schurdak ME, Taylor DL. Gough AH, et al. Among authors: schurdak me. PLoS One. 2014 Jul 18;9(7):e102678. doi: 10.1371/journal.pone.0102678. eCollection 2014. PLoS One. 2014. PMID: 25036749 Free PMC article.

3

Biologically Relevant Heterogeneity: Metrics and Practical Insights.

Gough A, Stern AM, Maier J, Lezon T, Shun TY, Chennubhotla C, Schurdak ME, Haney SA, Taylor DL. Gough A, et al. Among authors: schurdak me. SLAS Discov. 2017 Mar;22(3):213-237. doi: 10.1177/2472555216682725. Epub 2017 Jan 6. SLAS Discov. 2017. PMID: 28231035 Free PMC article. Review.

4

Integrating Analysis of Cellular Heterogeneity in High-Content Dose-Response Studies.

Gough A, Shun TY, Taylor DL, Schurdak M. Gough A, et al. Among authors: schurdak m. Methods Mol Biol. 2018;1745:25-46. doi: 10.1007/978-1-4939-7680-5_2. Methods Mol Biol. 2018. PMID: 29476461

5

A High-Throughput Assay for DNA Replication Inhibitors Based upon Multivariate Analysis of Yeast Growth Kinetics.

Ngo M, Wechter N, Tsai E, Shun TY, Gough A, Schurdak ME, Schwacha A, Vogt A. Ngo M, et al. Among authors: schurdak me. SLAS Discov. 2019 Jul;24(6):669-681. doi: 10.1177/2472555219829740. Epub 2019 Feb 25. SLAS Discov. 2019. PMID: 30802412 Free PMC article.

6

Harnessing Human Microphysiology Systems as Key Experimental Models for Quantitative Systems Pharmacology.

Taylor DL, Gough A, Schurdak ME, Vernetti L, Chennubhotla CS, Lefever D, Pei F, Faeder JR, Lezon TR, Stern AM, Bahar I. Taylor DL, et al. Among authors: schurdak me. Handb Exp Pharmacol. 2019;260:327-367. doi: 10.1007/164_2019_239. Handb Exp Pharmacol. 2019. PMID: 31201557 Free PMC article.

7

Applications of the microphysiology systems database for experimental ADME-Tox and disease models.

Schurdak M, Vernetti L, Bergenthal L, Wolter QK, Shun TY, Karcher S, Taylor DL, Gough A. Schurdak M, et al. Lab Chip. 2020 Apr 14;20(8):1472-1492. doi: 10.1039/c9lc01047e. Lab Chip. 2020. PMID: 32211684 Free PMC article.

8

Analysis of reproducibility and robustness of a human microfluidic four-cell liver acinus microphysiology system (LAMPS).

Sakolish C, Reese CE, Luo YS, Valdiviezo A, Schurdak ME, Gough A, Taylor DL, Chiu WA, Vernetti LA, Rusyn I. Sakolish C, et al. Among authors: schurdak me. Toxicology. 2021 Jan 30;448:152651. doi: 10.1016/j.tox.2020.152651. Epub 2020 Dec 8. Toxicology. 2021. PMID: 33307106 Free PMC article.

9

A metabolic-dysfunction associated steatotic liver acinus biomimetic induces pancreatic islet dysfunction in a coupled microphysiology system.

Aleman J, Ravikumar K, Wiegand C, Schurdak ME, Vernetti L, Gavlock D, Reese C, DeBiasio R, LaRocca G, Angarita YD, Gough A, Soto-Gutierrez A, Behari J, Yechoor V, Miedel MT, Stern AM, Banerjee I, Taylor DL. Aleman J, et al. Among authors: schurdak me. bioRxiv [Preprint]. 2024 Apr 30:2024.04.22.590598. doi: 10.1101/2024.04.22.590598. bioRxiv. 2024. Update in: Commun Biol. 2024 Oct 14;7(1):1317. doi: 10.1038/s42003-024-07006-7 PMID: 38712135 Free PMC article. Updated. Preprint.

10

Statin-induced mevalonate pathway inhibition attenuates the growth of mesenchymal-like cancer cells that lack functional E-cadherin mediated cell cohesion.

Warita K, Warita T, Beckwitt CH, Schurdak ME, Vazquez A, Wells A, Oltvai ZN. Warita K, et al. Sci Rep. 2014 Dec 23;4:7593. doi: 10.1038/srep07593. Sci Rep. 2014. PMID: 25534349 Free PMC article.

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