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Autologous stem cell transplantation aids autoimmune patients by functional renewal and TCR diversification of regulatory T cells.
Delemarre EM, van den Broek T, Mijnheer G, Meerding J, Wehrens EJ, Olek S, Boes M, van Herwijnen MJ, Broere F, van Royen A, Wulffraat NM, Prakken BJ, Spierings E, van Wijk F. Delemarre EM, et al. Among authors: olek s. Blood. 2016 Jan 7;127(1):91-101. doi: 10.1182/blood-2015-06-649145. Epub 2015 Oct 19. Blood. 2016. PMID: 26480932 Free article.
Quantitative DNA methylation analysis of FOXP3 as a new method for counting regulatory T cells in peripheral blood and solid tissue.
Wieczorek G, Asemissen A, Model F, Turbachova I, Floess S, Liebenberg V, Baron U, Stauch D, Kotsch K, Pratschke J, Hamann A, Loddenkemper C, Stein H, Volk HD, Hoffmüller U, Grützkau A, Mustea A, Huehn J, Scheibenbogen C, Olek S. Wieczorek G, et al. Among authors: olek s. Cancer Res. 2009 Jan 15;69(2):599-608. doi: 10.1158/0008-5472.CAN-08-2361. Cancer Res. 2009. PMID: 19147574
Wild-type FOXP3 is selectively active in CD4+CD25(hi) regulatory T cells of healthy female carriers of different FOXP3 mutations.
Di Nunzio S, Cecconi M, Passerini L, McMurchy AN, Baron U, Turbachova I, Vignola S, Valencic E, Tommasini A, Junker A, Cazzola G, Olek S, Levings MK, Perroni L, Roncarolo MG, Bacchetta R. Di Nunzio S, et al. Among authors: olek s. Blood. 2009 Nov 5;114(19):4138-41. doi: 10.1182/blood-2009-04-214593. Epub 2009 Sep 8. Blood. 2009. PMID: 19738030 Free article.
Origin of Enriched Regulatory T Cells in Patients Receiving Combined Kidney-Bone Marrow Transplantation to Induce Transplantation Tolerance.
Sprangers B, DeWolf S, Savage TM, Morokata T, Obradovic A, LoCascio SA, Shonts B, Zuber J, Lau SP, Shah R, Morris H, Steshenko V, Zorn E, Preffer FI, Olek S, Dombkowski DM, Turka LA, Colvin R, Winchester R, Kawai T, Sykes M. Sprangers B, et al. Among authors: olek s. Am J Transplant. 2017 Aug;17(8):2020-2032. doi: 10.1111/ajt.14251. Epub 2017 Apr 10. Am J Transplant. 2017. PMID: 28251801 Free PMC article.
Treatment with rapamycin can restore regulatory T-cell function in IPEX patients.
Passerini L, Barzaghi F, Curto R, Sartirana C, Barera G, Tucci F, Albarello L, Mariani A, Testoni PA, Bazzigaluppi E, Bosi E, Lampasona V, Neth O, Zama D, Hoenig M, Schulz A, Seidel MG, Rabbone I, Olek S, Roncarolo MG, Cicalese MP, Aiuti A, Bacchetta R. Passerini L, et al. Among authors: olek s. J Allergy Clin Immunol. 2020 Apr;145(4):1262-1271.e13. doi: 10.1016/j.jaci.2019.11.043. Epub 2019 Dec 23. J Allergy Clin Immunol. 2020. PMID: 31874182 Free article.
Identification of unstable regulatory and autoreactive effector T cells that are expanded in patients with FOXP3 mutations.
Borna Š, Lee E, Nideffer J, Ramachandran A, Wang B, Baker J, Mavers M, Lakshmanan U, Narula M, Garrett AK, Schulze J, Olek S, Marois L, Gernez Y, Bhatia M, Chong HJ, Walter J, Kitcharoensakkul M, Lang A, Cooper MA, Bertaina A, Roncarolo MG, Meffre E, Bacchetta R. Borna Š, et al. Among authors: olek s. Sci Transl Med. 2023 Dec 20;15(727):eadg6822. doi: 10.1126/scitranslmed.adg6822. Epub 2023 Dec 20. Sci Transl Med. 2023. PMID: 38117899 Free PMC article.
Epigenetic control of the foxp3 locus in regulatory T cells.
Floess S, Freyer J, Siewert C, Baron U, Olek S, Polansky J, Schlawe K, Chang HD, Bopp T, Schmitt E, Klein-Hessling S, Serfling E, Hamann A, Huehn J. Floess S, et al. Among authors: olek s. PLoS Biol. 2007 Feb;5(2):e38. doi: 10.1371/journal.pbio.0050038. PLoS Biol. 2007. PMID: 17298177 Free PMC article.
86 results