Hoover J - Search Results

1

Pharmacokinetics/Pharmacodynamics of Peptide Deformylase Inhibitor GSK1322322 against Streptococcus pneumoniae, Haemophilus influenzae, and Staphylococcus aureus in Rodent Models of Infection.

Hoover J, Lewandowski T, Straub RJ, Novick SJ, DeMarsh P, Aubart K, Rittenhouse S, Zalacain M. Hoover J, et al. Antimicrob Agents Chemother. 2015 Oct 19;60(1):180-9. doi: 10.1128/AAC.01842-15. Print 2016 Jan. Antimicrob Agents Chemother. 2015. PMID: 26482300 Free PMC article.

2

A Robust Pneumonia Model in Immunocompetent Rodents to Evaluate Antibacterial Efficacy against S. pneumoniae, H. influenzae, K. pneumoniae, P. aeruginosa or A. baumannii.

Hoover JL, Lewandowski TF, Mininger CL, Singley CM, Sucoloski S, Rittenhouse S. Hoover JL, et al. J Vis Exp. 2017 Jan 2;(119):55068. doi: 10.3791/55068. J Vis Exp. 2017. PMID: 28117818 Free PMC article.

3

Use of the surgical wound infection model to determine the efficacious dosing regimen of retapamulin, a novel topical antibiotic.

Rittenhouse S, Singley C, Hoover J, Page R, Payne D. Rittenhouse S, et al. Among authors: hoover j. Antimicrob Agents Chemother. 2006 Nov;50(11):3886-8. doi: 10.1128/AAC.00183-06. Antimicrob Agents Chemother. 2006. PMID: 17065626 Free PMC article.

4

Efficacy of Cefiderocol against Carbapenem-Resistant Gram-Negative Bacilli in Immunocompetent-Rat Respiratory Tract Infection Models Recreating Human Plasma Pharmacokinetics.

Matsumoto S, Singley CM, Hoover J, Nakamura R, Echols R, Rittenhouse S, Tsuji M, Yamano Y. Matsumoto S, et al. Among authors: hoover j. Antimicrob Agents Chemother. 2017 Aug 24;61(9):e00700-17. doi: 10.1128/AAC.00700-17. Print 2017 Sep. Antimicrob Agents Chemother. 2017. PMID: 28630178 Free PMC article.

5

Reducing Antibacterial Development Risk for GSK1322322 by Exploring Potential Human Dose Regimens in Nonclinical Efficacy Studies Using Immunocompetent Rats.

Hoover JL, Singley CM, Elefante P, DeMarsh P, Zalacain M, Rittenhouse S. Hoover JL, et al. Antimicrob Agents Chemother. 2017 Oct 24;61(11):e00959-17. doi: 10.1128/AAC.00959-17. Print 2017 Nov. Antimicrob Agents Chemother. 2017. PMID: 28807913 Free PMC article.

6

Efficacy of Human Exposures of Gepotidacin (GSK2140944) against Escherichia coli in a Rat Pyelonephritis Model.

Hoover JL, Singley CM, Elefante P, Rittenhouse S. Hoover JL, et al. Antimicrob Agents Chemother. 2019 Jun 24;63(7):e00086-19. doi: 10.1128/AAC.00086-19. Print 2019 Jul. Antimicrob Agents Chemother. 2019. PMID: 31061153 Free PMC article.

7

Comparative bacteriological efficacy of pharmacokinetically enhanced amoxicillin-clavulanate against Streptococcus pneumoniae with elevated amoxicillin MICs and Haemophilus influenzae.

Berry V, Hoover J, Singley C, Woodnutt G. Berry V, et al. Among authors: hoover j. Antimicrob Agents Chemother. 2005 Mar;49(3):908-15. doi: 10.1128/AAC.49.3.908-915.2005. Antimicrob Agents Chemother. 2005. PMID: 15728883 Free PMC article.

8

Pharmacokinetic-Pharmacodynamic Evaluation of Gepotidacin against Gram-Positive Organisms Using Data from Murine Infection Models.

Bulik CC, Okusanya ÓO, Lakota EA, Forrest A, Bhavnani SM, Hoover JL, Andes DR, Ambrose PG. Bulik CC, et al. Antimicrob Agents Chemother. 2017 Jan 24;61(2):e00115-16. doi: 10.1128/AAC.00115-16. Print 2017 Feb. Antimicrob Agents Chemother. 2017. PMID: 27872075 Free PMC article.

9

Generating Robust and Informative Nonclinical In Vitro and In Vivo Bacterial Infection Model Efficacy Data To Support Translation to Humans.

Bulitta JB, Hope WW, Eakin AE, Guina T, Tam VH, Louie A, Drusano GL, Hoover JL. Bulitta JB, et al. Antimicrob Agents Chemother. 2019 Apr 25;63(5):e02307-18. doi: 10.1128/AAC.02307-18. Print 2019 May. Antimicrob Agents Chemother. 2019. PMID: 30833428 Free PMC article. Review.

10

Novel amino-piperidines as potent antibacterials targeting bacterial type IIA topoisomerases.

Miles TJ, Axten JM, Barfoot C, Brooks G, Brown P, Chen D, Dabbs S, Davies DT, Downie DL, Eyrisch S, Gallagher T, Giordano I, Gwynn MN, Hennessy A, Hoover J, Huang J, Jones G, Markwell R, Miller WH, Minthorn EA, Rittenhouse S, Seefeld M, Pearson N. Miles TJ, et al. Among authors: hoover j. Bioorg Med Chem Lett. 2011 Dec 15;21(24):7489-95. doi: 10.1016/j.bmcl.2011.09.117. Epub 2011 Oct 10. Bioorg Med Chem Lett. 2011. PMID: 22047689

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