Raleigh DP - Search Results

1

Matrix Metalloproteinase-9 Protects Islets from Amyloid-induced Toxicity.

Meier DT, Tu LH, Zraika S, Hogan MF, Templin AT, Hull RL, Raleigh DP, Kahn SE. Meier DT, et al. Among authors: raleigh dp. J Biol Chem. 2015 Dec 18;290(51):30475-85. doi: 10.1074/jbc.M115.676692. Epub 2015 Oct 19. J Biol Chem. 2015. PMID: 26483547 Free PMC article.

2

Destabilization of human IAPP amyloid fibrils by proline mutations outside of the putative amyloidogenic domain: is there a critical amyloidogenic domain in human IAPP?

Abedini A, Raleigh DP. Abedini A, et al. Among authors: raleigh dp. J Mol Biol. 2006 Jan 13;355(2):274-81. doi: 10.1016/j.jmb.2005.10.052. Epub 2005 Nov 8. J Mol Biol. 2006. PMID: 16303136

3

The role of His-18 in amyloid formation by human islet amyloid polypeptide.

Abedini A, Raleigh DP. Abedini A, et al. Among authors: raleigh dp. Biochemistry. 2005 Dec 13;44(49):16284-91. doi: 10.1021/bi051432v. Biochemistry. 2005. PMID: 16331989

4

Characterization of the heparin binding site in the N-terminus of human pro-islet amyloid polypeptide: implications for amyloid formation.

Abedini A, Tracz SM, Cho JH, Raleigh DP. Abedini A, et al. Among authors: raleigh dp. Biochemistry. 2006 Aug 1;45(30):9228-37. doi: 10.1021/bi0510936. Biochemistry. 2006. PMID: 16866369

5

Aromatic interactions are not required for amyloid fibril formation by islet amyloid polypeptide but do influence the rate of fibril formation and fibril morphology.

Marek P, Abedini A, Song B, Kanungo M, Johnson ME, Gupta R, Zaman W, Wong SS, Raleigh DP. Marek P, et al. Among authors: raleigh dp. Biochemistry. 2007 Mar 20;46(11):3255-61. doi: 10.1021/bi0621967. Epub 2007 Feb 21. Biochemistry. 2007. PMID: 17311418

6

Amyloid formation by pro-islet amyloid polypeptide processing intermediates: examination of the role of protein heparan sulfate interactions and implications for islet amyloid formation in type 2 diabetes.

Meng F, Abedini A, Song B, Raleigh DP. Meng F, et al. Among authors: raleigh dp. Biochemistry. 2007 Oct 30;46(43):12091-9. doi: 10.1021/bi7004834. Epub 2007 Oct 9. Biochemistry. 2007. PMID: 17924651

7

Rifampicin does not prevent amyloid fibril formation by human islet amyloid polypeptide but does inhibit fibril thioflavin-T interactions: implications for mechanistic studies of beta-cell death.

Meng F, Marek P, Potter KJ, Verchere CB, Raleigh DP. Meng F, et al. Among authors: raleigh dp. Biochemistry. 2008 Jun 3;47(22):6016-24. doi: 10.1021/bi702518m. Epub 2008 May 6. Biochemistry. 2008. PMID: 18457428

8

Two-dimensional infrared spectroscopy provides evidence of an intermediate in the membrane-catalyzed assembly of diabetic amyloid.

Ling YL, Strasfeld DB, Shim SH, Raleigh DP, Zanni MT. Ling YL, et al. Among authors: raleigh dp. J Phys Chem B. 2009 Feb 26;113(8):2498-505. doi: 10.1021/jp810261x. J Phys Chem B. 2009. PMID: 19182939 Free PMC article.

9

Strategies for extracting structural information from 2D IR spectroscopy of amyloid: application to islet amyloid polypeptide.

Strasfeld DB, Ling YL, Gupta R, Raleigh DP, Zanni MT. Strasfeld DB, et al. Among authors: raleigh dp. J Phys Chem B. 2009 Nov 26;113(47):15679-91. doi: 10.1021/jp9072203. J Phys Chem B. 2009. PMID: 19883093 Free PMC article.

10

The ability of rodent islet amyloid polypeptide to inhibit amyloid formation by human islet amyloid polypeptide has important implications for the mechanism of amyloid formation and the design of inhibitors.

Cao P, Meng F, Abedini A, Raleigh DP. Cao P, et al. Among authors: raleigh dp. Biochemistry. 2010 Feb 9;49(5):872-81. doi: 10.1021/bi901751b. Biochemistry. 2010. PMID: 20028124 Free PMC article.

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