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Page 1
Hit Optimization of 5-Substituted-N-(piperidin-4-ylmethyl)-1H-indazole-3-carboxamides: Potent Glycogen Synthase Kinase-3 (GSK-3) Inhibitors with in Vivo Activity in Model of Mood Disorders.
Furlotti G, Alisi MA, Cazzolla N, Dragone P, Durando L, Magarò G, Mancini F, Mangano G, Ombrato R, Vitiello M, Armirotti A, Capurro V, Lanfranco M, Ottonello G, Summa M, Reggiani A. Furlotti G, et al. Among authors: cazzolla n. J Med Chem. 2015 Nov 25;58(22):8920-37. doi: 10.1021/acs.jmedchem.5b01208. Epub 2015 Nov 13. J Med Chem. 2015. PMID: 26486317
New anti-viral drugs for the treatment of the common cold.
Maugeri C, Alisi MA, Apicella C, Cellai L, Dragone P, Fioravanzo E, Florio S, Furlotti G, Mangano G, Ombrato R, Luisi R, Pompei R, Rincicotti V, Russo V, Vitiello M, Cazzolla N. Maugeri C, et al. Among authors: cazzolla n. Bioorg Med Chem. 2008 Mar 15;16(6):3091-107. doi: 10.1016/j.bmc.2007.12.030. Epub 2007 Dec 23. Bioorg Med Chem. 2008. PMID: 18248816
Discovery and pharmacological profile of new 1H-indazole-3-carboxamide and 2H-pyrrolo[3,4-c]quinoline derivatives as selective serotonin 4 receptor ligands.
Furlotti G, Alisi MA, Apicella C, Capezzone de Joannon A, Cazzolla N, Costi R, Cuzzucoli Crucitti G, Garrone B, Iacovo A, Magarò G, Mangano G, Miele G, Ombrato R, Pescatori L, Polenzani L, Rosi F, Vitiello M, Di Santo R. Furlotti G, et al. Among authors: cazzolla n. J Med Chem. 2012 Nov 26;55(22):9446-66. doi: 10.1021/jm300573d. Epub 2012 Oct 24. J Med Chem. 2012. PMID: 23043420
Targeting Serotonin 2A and Adrenergic α1 Receptors for Ocular Antihypertensive Agents: Discovery of 3,4-Dihydropyrazino[1,2-b]indazol-1(2H)-one Derivatives.
Furlotti G, Alisi MA, Cazzolla N, Ceccacci F, Garrone B, Gasperi T, La Bella A, Leonelli F, Loreto MA, Magarò G, Mangano G, Bettolo RM, Masini E, Miceli M, Migneco LM, Vitiello M. Furlotti G, et al. Among authors: cazzolla n. ChemMedChem. 2018 Aug 10;13(15):1597-1607. doi: 10.1002/cmdc.201800199. Epub 2018 Jul 9. ChemMedChem. 2018. PMID: 29873449
11 results