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Hit Optimization of 5-Substituted-N-(piperidin-4-ylmethyl)-1H-indazole-3-carboxamides: Potent Glycogen Synthase Kinase-3 (GSK-3) Inhibitors with in Vivo Activity in Model of Mood Disorders.
Furlotti G, Alisi MA, Cazzolla N, Dragone P, Durando L, Magarò G, Mancini F, Mangano G, Ombrato R, Vitiello M, Armirotti A, Capurro V, Lanfranco M, Ottonello G, Summa M, Reggiani A. Furlotti G, et al. Among authors: durando l. J Med Chem. 2015 Nov 25;58(22):8920-37. doi: 10.1021/acs.jmedchem.5b01208. Epub 2015 Nov 13. J Med Chem. 2015. PMID: 26486317
The mood stabilizing properties of AF3581, a novel potent GSK-3β inhibitor.
Capurro V, Lanfranco M, Summa M, Porceddu PF, Ciampoli M, Margaroli N, Durando L, Garrone B, Ombrato R, Tongiani S, Reggiani A. Capurro V, et al. Among authors: durando l. Biomed Pharmacother. 2020 Aug;128:110249. doi: 10.1016/j.biopha.2020.110249. Epub 2020 May 26. Biomed Pharmacother. 2020. PMID: 32470749 Free article.
15 results