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Hit Optimization of 5-Substituted-N-(piperidin-4-ylmethyl)-1H-indazole-3-carboxamides: Potent Glycogen Synthase Kinase-3 (GSK-3) Inhibitors with in Vivo Activity in Model of Mood Disorders.
Furlotti G, Alisi MA, Cazzolla N, Dragone P, Durando L, Magarò G, Mancini F, Mangano G, Ombrato R, Vitiello M, Armirotti A, Capurro V, Lanfranco M, Ottonello G, Summa M, Reggiani A. Furlotti G, et al. Among authors: mancini f. J Med Chem. 2015 Nov 25;58(22):8920-37. doi: 10.1021/acs.jmedchem.5b01208. Epub 2015 Nov 13. J Med Chem. 2015. PMID: 26486317
Proneurogenic Effects of Trazodone in Murine and Human Neural Progenitor Cells.
Bortolotto V, Mancini F, Mangano G, Salem R, Xia E, Del Grosso E, Bianchi M, Canonico PL, Polenzani L, Grilli M. Bortolotto V, et al. Among authors: mancini f. ACS Chem Neurosci. 2017 Sep 20;8(9):2027-2038. doi: 10.1021/acschemneuro.7b00175. Epub 2017 Jul 3. ACS Chem Neurosci. 2017. PMID: 28636360 Free article.
From AChE to BACE1 inhibitors: The role of the amine on the indanone scaffold.
Rampa A, Mancini F, De Simone A, Falchi F, Belluti F, Di Martino RM, Gobbi S, Andrisano V, Tarozzi A, Bartolini M, Cavalli A, Bisi A. Rampa A, et al. Among authors: mancini f. Bioorg Med Chem Lett. 2015 Jul 15;25(14):2804-8. doi: 10.1016/j.bmcl.2015.05.002. Epub 2015 May 9. Bioorg Med Chem Lett. 2015. PMID: 26003339
Aryl-substituted methyleneaminoxymethyl (MAOM) analogues of diarylcyclopentenyl cyclooxygenase-2 inhibitors: effects of some structural modifications on their biological properties.
Balsamo A, Coletta I, Guglielmotti A, Landolfi C, Lapucci A, Mancini F, Milanese C, Minutolo F, Orlandini E, Ortore G, Pinza M, Rapposelli S. Balsamo A, et al. Among authors: mancini f. Eur J Med Chem. 2002 Jul;37(7):585-94. doi: 10.1016/s0223-5234(02)01385-5. Eur J Med Chem. 2002. PMID: 12126777
(E)-[2-(4-Methylsulphonylphenyl)-1-cyclopentenyl-1-methyliden](arylmethyloxy)amines. Methyleneaminoxymethyl (MAOM) analogues of diarylcyclopentenyl cyclooxygenase-2 inhibitors: synthesis and biological properties.
Balsamo A, Coletta I, Domiano P, Guglielmotti A, Landolfi C, Mancini F, Milanese C, Orlandini E, Rapposelli S, Pinza M, Macchia B. Balsamo A, et al. Among authors: mancini f. Eur J Med Chem. 2002 May;37(5):391-8. doi: 10.1016/s0223-5234(02)01359-4. Eur J Med Chem. 2002. PMID: 12008053
837 results