Bollini M - Search Results

1

Potent Inhibitors Active against HIV Reverse Transcriptase with K101P, a Mutation Conferring Rilpivirine Resistance.

Gray WT, Frey KM, Laskey SB, Mislak AC, Spasov KA, Lee WG, Bollini M, Siliciano RF, Jorgensen WL, Anderson KS. Gray WT, et al. Among authors: bollini m. ACS Med Chem Lett. 2015 Aug 31;6(10):1075-9. doi: 10.1021/acsmedchemlett.5b00254. eCollection 2015 Oct 8. ACS Med Chem Lett. 2015. PMID: 26487915 Free PMC article.

2

Eastern extension of azoles as non-nucleoside inhibitors of HIV-1 reverse transcriptase; cyano group alternatives.

Leung CS, Zeevaart JG, Domaoal RA, Bollini M, Thakur VV, Spasov KA, Anderson KS, Jorgensen WL. Leung CS, et al. Among authors: bollini m. Bioorg Med Chem Lett. 2010 Apr 15;20(8):2485-8. doi: 10.1016/j.bmcl.2010.03.006. Epub 2010 Mar 4. Bioorg Med Chem Lett. 2010. PMID: 20304641 Free PMC article.

3

Efficient discovery of potent anti-HIV agents targeting the Tyr181Cys variant of HIV reverse transcriptase.

Jorgensen WL, Bollini M, Thakur VV, Domaoal RA, Spasov KA, Anderson KS. Jorgensen WL, et al. Among authors: bollini m. J Am Chem Soc. 2011 Oct 5;133(39):15686-96. doi: 10.1021/ja2058583. Epub 2011 Sep 9. J Am Chem Soc. 2011. PMID: 21853995 Free PMC article.

4

Computationally-guided optimization of a docking hit to yield catechol diethers as potent anti-HIV agents.

Bollini M, Domaoal RA, Thakur VV, Gallardo-Macias R, Spasov KA, Anderson KS, Jorgensen WL. Bollini M, et al. J Med Chem. 2011 Dec 22;54(24):8582-91. doi: 10.1021/jm201134m. Epub 2011 Nov 29. J Med Chem. 2011. PMID: 22081993 Free PMC article.

5

Discovery of dimeric inhibitors by extension into the entrance channel of HIV-1 reverse transcriptase.

Ekkati AR, Bollini M, Domaoal RA, Spasov KA, Anderson KS, Jorgensen WL. Ekkati AR, et al. Among authors: bollini m. Bioorg Med Chem Lett. 2012 Feb 15;22(4):1565-8. doi: 10.1016/j.bmcl.2011.12.132. Epub 2012 Jan 5. Bioorg Med Chem Lett. 2012. PMID: 22269110 Free PMC article.

6

Crystal structures of HIV-1 reverse transcriptase with picomolar inhibitors reveal key interactions for drug design.

Frey KM, Bollini M, Mislak AC, Cisneros JA, Gallardo-Macias R, Jorgensen WL, Anderson KS. Frey KM, et al. Among authors: bollini m. J Am Chem Soc. 2012 Dec 5;134(48):19501-3. doi: 10.1021/ja3092642. Epub 2012 Nov 19. J Am Chem Soc. 2012. PMID: 23163887 Free PMC article.

7

Optimization of benzyloxazoles as non-nucleoside inhibitors of HIV-1 reverse transcriptase to enhance Y181C potency.

Bollini M, Gallardo-Macias R, Spasov KA, Tirado-Rives J, Anderson KS, Jorgensen WL. Bollini M, et al. Bioorg Med Chem Lett. 2013 Feb 15;23(4):1110-3. doi: 10.1016/j.bmcl.2012.11.115. Epub 2012 Dec 12. Bioorg Med Chem Lett. 2013. PMID: 23298809 Free PMC article.

8

Extension into the entrance channel of HIV-1 reverse transcriptase--crystallography and enhanced solubility.

Bollini M, Frey KM, Cisneros JA, Spasov KA, Das K, Bauman JD, Arnold E, Anderson KS, Jorgensen WL. Bollini M, et al. Bioorg Med Chem Lett. 2013 Sep 15;23(18):5209-12. doi: 10.1016/j.bmcl.2013.06.093. Epub 2013 Jul 8. Bioorg Med Chem Lett. 2013. PMID: 23899617 Free PMC article.

9

Optimization of diarylazines as anti-HIV agents with dramatically enhanced solubility.

Bollini M, Cisneros JA, Spasov KA, Anderson KS, Jorgensen WL. Bollini M, et al. Bioorg Med Chem Lett. 2013 Sep 15;23(18):5213-6. doi: 10.1016/j.bmcl.2013.06.091. Epub 2013 Jul 8. Bioorg Med Chem Lett. 2013. PMID: 23937980 Free PMC article.

10

Picomolar inhibitors of HIV reverse transcriptase featuring bicyclic replacement of a cyanovinylphenyl group.

Lee WG, Gallardo-Macias R, Frey KM, Spasov KA, Bollini M, Anderson KS, Jorgensen WL. Lee WG, et al. Among authors: bollini m. J Am Chem Soc. 2013 Nov 6;135(44):16705-13. doi: 10.1021/ja408917n. Epub 2013 Oct 24. J Am Chem Soc. 2013. PMID: 24151856 Free PMC article.

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