D'Orso I - Search Results

1

HIV Tat controls RNA Polymerase II and the epigenetic landscape to transcriptionally reprogram target immune cells.

Reeder JE, Kwak YT, McNamara RP, Forst CV, D'Orso I. Reeder JE, et al. Elife. 2015 Oct 21;4:e08955. doi: 10.7554/eLife.08955. Elife. 2015. PMID: 26488441 Free PMC article.

2

Transcription factors mediate the enzymatic disassembly of promoter-bound 7SK snRNP to locally recruit P-TEFb for transcription elongation.

McNamara RP, McCann JL, Gudipaty SA, D'Orso I. McNamara RP, et al. Cell Rep. 2013 Dec 12;5(5):1256-68. doi: 10.1016/j.celrep.2013.11.003. Epub 2013 Dec 5. Cell Rep. 2013. PMID: 24316072 Free PMC article.

3

PPM1G Binds 7SK RNA and Hexim1 To Block P-TEFb Assembly into the 7SK snRNP and Sustain Transcription Elongation.

Gudipaty SA, McNamara RP, Morton EL, D'Orso I. Gudipaty SA, et al. Mol Cell Biol. 2015 Nov;35(22):3810-28. doi: 10.1128/MCB.00226-15. Epub 2015 Aug 31. Mol Cell Biol. 2015. PMID: 26324325 Free PMC article.

4

KAP1 Recruitment of the 7SK snRNP Complex to Promoters Enables Transcription Elongation by RNA Polymerase II.

McNamara RP, Reeder JE, McMillan EA, Bacon CW, McCann JL, D'Orso I. McNamara RP, et al. Mol Cell. 2016 Jan 7;61(1):39-53. doi: 10.1016/j.molcel.2015.11.004. Epub 2015 Dec 24. Mol Cell. 2016. PMID: 26725010 Free PMC article.

5

Genome-wide analysis of KAP1, the 7SK snRNP complex, and RNA polymerase II.

McNamara RP, Guzman C, Reeder JE, D'Orso I. McNamara RP, et al. Genom Data. 2016 Feb 4;7:250-5. doi: 10.1016/j.gdata.2016.01.019. eCollection 2016 Mar. Genom Data. 2016. PMID: 26981421 Free PMC article.

6

Transcription elongation control by the 7SK snRNP complex: Releasing the pause.

McNamara RP, Bacon CW, D'Orso I. McNamara RP, et al. Cell Cycle. 2016 Aug 17;15(16):2115-2123. doi: 10.1080/15384101.2016.1181241. Epub 2016 May 6. Cell Cycle. 2016. PMID: 27152730 Free PMC article. Review.

7

The HIV-1 Tat protein recruits a ubiquitin ligase to reorganize the 7SK snRNP for transcriptional activation.

Faust TB, Li Y, Bacon CW, Jang GM, Weiss A, Jayaraman B, Newton BW, Krogan NJ, D'Orso I, Frankel AD. Faust TB, et al. Elife. 2018 May 30;7:e31879. doi: 10.7554/eLife.31879. Elife. 2018. PMID: 29845934 Free PMC article.

8

Transcriptional Circuit Fragility Influences HIV Proviral Fate.

Morton EL, Forst CV, Zheng Y, DePaula-Silva AB, Ramirez NP, Planelles V, D'Orso I. Morton EL, et al. Cell Rep. 2019 Apr 2;27(1):154-171.e9. doi: 10.1016/j.celrep.2019.03.007. Cell Rep. 2019. PMID: 30943398 Free PMC article.

9

HIV-1 Proviral Transcription and Latency in the New Era.

Shukla A, Ramirez NP, D'Orso I. Shukla A, et al. Viruses. 2020 May 18;12(5):555. doi: 10.3390/v12050555. Viruses. 2020. PMID: 32443452 Free PMC article. Review.

10

Mathematical Models of HIV-1 Dynamics, Transcription, and Latency.

D'Orso I, Forst CV. D'Orso I, et al. Viruses. 2023 Oct 19;15(10):2119. doi: 10.3390/v15102119. Viruses. 2023. PMID: 37896896 Free PMC article. Review.

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