Wagner JM - Search Results

1

Genomically Incorporated 5-Fluorouracil that Escapes UNG-Initiated Base Excision Repair Blocks DNA Replication and Activates Homologous Recombination.

Huehls AM, Huntoon CJ, Joshi PM, Baehr CA, Wagner JM, Wang X, Lee MY, Karnitz LM. Huehls AM, et al. Among authors: wagner jm. Mol Pharmacol. 2016 Jan;89(1):53-62. doi: 10.1124/mol.115.100164. Epub 2015 Oct 22. Mol Pharmacol. 2016. PMID: 26494862 Free PMC article.

2

Cisplatin-induced DNA damage activates replication checkpoint signaling components that differentially affect tumor cell survival.

Wagner JM, Karnitz LM. Wagner JM, et al. Mol Pharmacol. 2009 Jul;76(1):208-14. doi: 10.1124/mol.109.055178. Epub 2009 Apr 29. Mol Pharmacol. 2009. PMID: 19403702 Free PMC article.

3

Poly(ADP-Ribose) polymerase inhibition synergizes with 5-fluorodeoxyuridine but not 5-fluorouracil in ovarian cancer cells.

Huehls AM, Wagner JM, Huntoon CJ, Geng L, Erlichman C, Patel AG, Kaufmann SH, Karnitz LM. Huehls AM, et al. Among authors: wagner jm. Cancer Res. 2011 Jul 15;71(14):4944-54. doi: 10.1158/0008-5472.CAN-11-0814. Epub 2011 May 25. Cancer Res. 2011. PMID: 21613406 Free PMC article.

4

Checkpoint signaling, base excision repair, and PARP promote survival of colon cancer cells treated with 5-fluorodeoxyuridine but not 5-fluorouracil.

Geng L, Huehls AM, Wagner JM, Huntoon CJ, Karnitz LM. Geng L, et al. Among authors: wagner jm. PLoS One. 2011;6(12):e28862. doi: 10.1371/journal.pone.0028862. Epub 2011 Dec 15. PLoS One. 2011. PMID: 22194930 Free PMC article.

5

Identification of DNA repair pathways that affect the survival of ovarian cancer cells treated with a poly(ADP-ribose) polymerase inhibitor in a novel drug combination.

Huehls AM, Wagner JM, Huntoon CJ, Karnitz LM. Huehls AM, et al. Among authors: wagner jm. Mol Pharmacol. 2012 Oct;82(4):767-76. doi: 10.1124/mol.112.080614. Epub 2012 Jul 25. Mol Pharmacol. 2012. PMID: 22833573 Free PMC article.

6

Gemcitabine-induced activation of checkpoint signaling pathways that affect tumor cell survival.

Karnitz LM, Flatten KS, Wagner JM, Loegering D, Hackbarth JS, Arlander SJ, Vroman BT, Thomas MB, Baek YU, Hopkins KM, Lieberman HB, Chen J, Cliby WA, Kaufmann SH. Karnitz LM, et al. Among authors: wagner jm. Mol Pharmacol. 2005 Dec;68(6):1636-44. doi: 10.1124/mol.105.012716. Epub 2005 Aug 26. Mol Pharmacol. 2005. PMID: 16126823

7

The Rad9-Hus1-Rad1 (9-1-1) clamp activates checkpoint signaling via TopBP1.

Delacroix S, Wagner JM, Kobayashi M, Yamamoto K, Karnitz LM. Delacroix S, et al. Among authors: wagner jm. Genes Dev. 2007 Jun 15;21(12):1472-7. doi: 10.1101/gad.1547007. Genes Dev. 2007. PMID: 17575048 Free PMC article.

8

Overcoming S-phase checkpoint-mediated resistance: sequence-dependent synergy of gemcitabine and 7-ethyl-10-hydroxycamptothecin (SN-38) in human carcinoma cell lines.

Gálvez-Peralta M, Dai NT, Loegering DA, Flatten KS, Safgren SL, Wagner JM, Ames MM, Karnitz LM, Kaufmann SH. Gálvez-Peralta M, et al. Among authors: wagner jm. Mol Pharmacol. 2008 Sep;74(3):724-35. doi: 10.1124/mol.108.047787. Epub 2008 May 28. Mol Pharmacol. 2008. PMID: 18509065 Free PMC article.

9

Chaperoning checkpoint kinase 1 (Chk1), an Hsp90 client, with purified chaperones.

Arlander SJ, Felts SJ, Wagner JM, Stensgard B, Toft DO, Karnitz LM. Arlander SJ, et al. Among authors: wagner jm. J Biol Chem. 2006 Feb 3;281(5):2989-98. doi: 10.1074/jbc.M508687200. Epub 2005 Dec 5. J Biol Chem. 2006. PMID: 16330544 Free article.

10

Characterization of a RAD51C-silenced high-grade serous ovarian cancer model during development of PARP inhibitor resistance.

Hurley RM, McGehee CD, Nesic K, Correia C, Weiskittel TM, Kelly RL, Venkatachalam A, Hou X, Pathoulas NM, Meng XW, Kondrashova O, Radke MR, Schneider PA, Flatten KS, Peterson KL, Becker MA, Wong EM, Southey MS, Dobrovic A, Lin KK, Harding TC, McNeish I, Ross CA, Wagner JM, Wakefield MJ, Scott CL, Haluska P, Wahner Hendrickson AE, Karnitz LM, Swisher EM, Li H, Weroha SJ, Kaufmann SH. Hurley RM, et al. Among authors: wagner jm. NAR Cancer. 2021 Jul 9;3(3):zcab028. doi: 10.1093/narcan/zcab028. eCollection 2021 Sep. NAR Cancer. 2021. PMID: 34316715 Free PMC article.

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