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PPARα gene expression correlates with severity and histological treatment response in patients with non-alcoholic steatohepatitis.
Francque S, Verrijken A, Caron S, Prawitt J, Paumelle R, Derudas B, Lefebvre P, Taskinen MR, Van Hul W, Mertens I, Hubens G, Van Marck E, Michielsen P, Van Gaal L, Staels B. Francque S, et al. Among authors: michielsen p. J Hepatol. 2015 Jul;63(1):164-73. doi: 10.1016/j.jhep.2015.02.019. Epub 2015 Feb 19. J Hepatol. 2015. PMID: 25703085
Screening for rare variants in the PNPLA3 gene in obese liver biopsy patients.
Zegers D, Verrijken A, Francque S, de Freitas F, Beckers S, Aerts E, Ruppert M, Hubens G, Michielsen P, Van Hul W, Van Gaal LF. Zegers D, et al. Among authors: michielsen p. Clin Res Hepatol Gastroenterol. 2016 Dec;40(6):715-721. doi: 10.1016/j.clinre.2016.05.004. Epub 2016 Jun 7. Clin Res Hepatol Gastroenterol. 2016. PMID: 27288299
Interspecies NASH disease activity whole-genome profiling identifies a fibrogenic role of PPARα-regulated dermatopontin.
Lefebvre P, Lalloyer F, Baugé E, Pawlak M, Gheeraert C, Dehondt H, Vanhoutte J, Woitrain E, Hennuyer N, Mazuy C, Bobowski-Gérard M, Zummo FP, Derudas B, Driessen A, Hubens G, Vonghia L, Kwanten WJ, Michielsen P, Vanwolleghem T, Eeckhoute J, Verrijken A, Van Gaal L, Francque S, Staels B. Lefebvre P, et al. Among authors: michielsen p. JCI Insight. 2017 Jul 6;2(13):e92264. doi: 10.1172/jci.insight.92264. eCollection 2017 Jul 6. JCI Insight. 2017. PMID: 28679947 Free PMC article.
307 results