Huang Y - Search Results

1

Design, synthesis, and antitumor evaluation of histone deacetylase inhibitors with L-phenylglycine scaffold.

Zhang Y, Li X, Hou J, Huang Y, Xu W. Zhang Y, et al. Among authors: huang y. Drug Des Devel Ther. 2015 Oct 8;9:5553-67. doi: 10.2147/DDDT.S94037. eCollection 2015. Drug Des Devel Ther. 2015. PMID: 26504374 Free PMC article.

2

Discovery of BC-01, a novel mutual prodrug (hybrid drug) of ubenimex and fluorouracil as anticancer agent.

Jiang Y, Li X, Hou J, Huang Y, Jia Y, Zou M, Zhang J, Wang X, Xu W, Zhang Y. Jiang Y, et al. Among authors: huang y. Eur J Med Chem. 2016 Oct 4;121:649-657. doi: 10.1016/j.ejmech.2016.05.068. Epub 2016 Jun 1. Eur J Med Chem. 2016. PMID: 27322756

3

Selective HDAC inhibitors with potent oral activity against leukemia and colorectal cancer: Design, structure-activity relationship and anti-tumor activity study.

Li X, Zhang Y, Jiang Y, Wu J, Inks ES, Chou CJ, Gao S, Hou J, Ding Q, Li J, Wang X, Huang Y, Xu W. Li X, et al. Among authors: huang y. Eur J Med Chem. 2017 Jul 7;134:185-206. doi: 10.1016/j.ejmech.2017.03.069. Epub 2017 Mar 30. Eur J Med Chem. 2017. PMID: 28415009 Free PMC article.

4

Synthesis and biological characterization of ubenimex-fluorouracil conjugates for anti-cancer therapy.

Jiang Y, Li X, Hou J, Huang Y, Wang X, Jia Y, Wang Q, Xu W, Zhang J, Zhang Y. Jiang Y, et al. Among authors: huang y. Eur J Med Chem. 2018 Jan 1;143:334-347. doi: 10.1016/j.ejmech.2017.11.074. Epub 2017 Dec 1. Eur J Med Chem. 2018. PMID: 29202398

5

Design, Synthesis, and Biological Evaluation of Pyrazoline-Based Hydroxamic Acid Derivatives as Aminopeptidase N (APN) Inhibitors.

Cao J, Zang J, Ma C, Li X, Hou J, Li J, Huang Y, Xu W, Wang B, Zhang Y. Cao J, et al. Among authors: huang y. ChemMedChem. 2018 Mar 6;13(5):431-436. doi: 10.1002/cmdc.201700690. Epub 2018 Feb 16. ChemMedChem. 2018. PMID: 29377564

6

Enhanced anticancer activity of 5-FU in combination with Bestatin: Evidence in human tumor-derived cell lines and an H22 tumor-bearing mouse.

Li J, Wang X, Hou J, Huang Y, Zhang Y, Xu W. Li J, et al. Among authors: huang y. Drug Discov Ther. 2015 Feb;9(1):45-52. doi: 10.5582/ddt.2015.01006. Drug Discov Ther. 2015. PMID: 25788051 Free article.

7

Novel leucine ureido derivatives as aminopeptidase N inhibitors. Design, synthesis and activity evaluation.

Ma C, Cao J, Liang X, Huang Y, Wu P, Li Y, Xu W, Zhang Y. Ma C, et al. Among authors: huang y. Eur J Med Chem. 2016 Jan 27;108:21-27. doi: 10.1016/j.ejmech.2015.11.021. Epub 2015 Nov 26. Eur J Med Chem. 2016. PMID: 26629857

8

LJNK, an indoline-2,3-dione-based aminopeptidase N inhibitor with promising antitumor potency.

Hou J, Jin K, Li J, Jiang Y, Li X, Wang X, Huang Y, Zhang Y, Xu W. Hou J, et al. Among authors: huang y. Anticancer Drugs. 2016 Jul;27(6):496-507. doi: 10.1097/CAD.0000000000000351. Anticancer Drugs. 2016. PMID: 26872309

9

Design, synthesis and preliminary biological evaluation of 4-aminopyrazole derivatives as novel and potent JAKs inhibitors.

Liang X, Huang Y, Zang J, Gao Q, Wang B, Xu W, Zhang Y. Liang X, et al. Among authors: huang y. Bioorg Med Chem. 2016 Jun 15;24(12):2660-72. doi: 10.1016/j.bmc.2016.04.030. Epub 2016 Apr 20. Bioorg Med Chem. 2016. PMID: 27137359

10

Discovery of a novel chimeric ubenimex-gemcitabine with potent oral antitumor activity.

Jiang Y, Hou J, Li X, Huang Y, Wang X, Wu J, Zhang J, Xu W, Zhang Y. Jiang Y, et al. Among authors: huang y. Bioorg Med Chem. 2016 Nov 15;24(22):5787-5795. doi: 10.1016/j.bmc.2016.09.033. Epub 2016 Sep 14. Bioorg Med Chem. 2016. PMID: 27670098

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