Zuo J - Search Results

1

Discovery of Small Molecules that Inhibit the Disordered Protein, p27(Kip1).

Iconaru LI, Ban D, Bharatham K, Ramanathan A, Zhang W, Shelat AA, Zuo J, Kriwacki RW. Iconaru LI, et al. Among authors: zuo j. Sci Rep. 2015 Oct 28;5:15686. doi: 10.1038/srep15686. Sci Rep. 2015. PMID: 26507530 Free PMC article.

2

A Small Molecule Causes a Population Shift in the Conformational Landscape of an Intrinsically Disordered Protein.

Ban D, Iconaru LI, Ramanathan A, Zuo J, Kriwacki RW. Ban D, et al. Among authors: zuo j. J Am Chem Soc. 2017 Oct 4;139(39):13692-13700. doi: 10.1021/jacs.7b01380. Epub 2017 Sep 21. J Am Chem Soc. 2017. PMID: 28885015 Free PMC article.

3

Small Molecule Sequestration of the Intrinsically Disordered Protein, p27^Kip1, Within Soluble Oligomers.

Iconaru LI, Das S, Nourse A, Shelat AA, Zuo J, Kriwacki RW. Iconaru LI, et al. Among authors: zuo j. J Mol Biol. 2021 Sep 3;433(18):167120. doi: 10.1016/j.jmb.2021.167120. Epub 2021 Jun 29. J Mol Biol. 2021. PMID: 34197833 Free PMC article.

4

CDK2 inhibitors as candidate therapeutics for cisplatin- and noise-induced hearing loss.

Teitz T, Fang J, Goktug AN, Bonga JD, Diao S, Hazlitt RA, Iconaru L, Morfouace M, Currier D, Zhou Y, Umans RA, Taylor MR, Cheng C, Min J, Freeman B, Peng J, Roussel MF, Kriwacki R, Guy RK, Chen T, Zuo J. Teitz T, et al. Among authors: zuo j. J Exp Med. 2018 Apr 2;215(4):1187-1203. doi: 10.1084/jem.20172246. Epub 2018 Mar 7. J Exp Med. 2018. PMID: 29514916 Free PMC article.

5

High-throughput screening reveals alsterpaullone, 2-cyanoethyl as a potent p27Kip1 transcriptional inhibitor.

Walters BJ, Lin W, Diao S, Brimble M, Iconaru LI, Dearman J, Goktug A, Chen T, Zuo J. Walters BJ, et al. Among authors: zuo j. PLoS One. 2014 Mar 19;9(3):e91173. doi: 10.1371/journal.pone.0091173. eCollection 2014. PLoS One. 2014. PMID: 24646893 Free PMC article.

6

Development of Second-Generation CDK2 Inhibitors for the Prevention of Cisplatin-Induced Hearing Loss.

Hazlitt RA, Teitz T, Bonga JD, Fang J, Diao S, Iconaru L, Yang L, Goktug AN, Currier DG, Chen T, Rankovic Z, Min J, Zuo J. Hazlitt RA, et al. Among authors: zuo j. J Med Chem. 2018 Sep 13;61(17):7700-7709. doi: 10.1021/acs.jmedchem.8b00669. Epub 2018 Aug 24. J Med Chem. 2018. PMID: 30091915 Free PMC article.

7

Pseudo-immortalization of postnatal cochlear progenitor cells yields a scalable cell line capable of transcriptionally regulating mature hair cell genes.

Walters BJ, Diao S, Zheng F, Walters BJ, Layman WS, Zuo J. Walters BJ, et al. Among authors: zuo j. Sci Rep. 2015 Dec 7;5:17792. doi: 10.1038/srep17792. Sci Rep. 2015. PMID: 26639154 Free PMC article.

8

Sox2-CreER mice are useful for fate mapping of mature, but not neonatal, cochlear supporting cells in hair cell regeneration studies.

Walters BJ, Yamashita T, Zuo J. Walters BJ, et al. Among authors: zuo j. Sci Rep. 2015 Jun 25;5:11621. doi: 10.1038/srep11621. Sci Rep. 2015. PMID: 26108463 Free PMC article.

9

Generation of Atoh1-rtTA transgenic mice: a tool for inducible gene expression in hair cells of the inner ear.

Cox BC, Dearman JA, Brancheck J, Zindy F, Roussel MF, Zuo J. Cox BC, et al. Among authors: zuo j. Sci Rep. 2014 Nov 3;4:6885. doi: 10.1038/srep06885. Sci Rep. 2014. PMID: 25363458 Free PMC article.

10

In Vivo Interplay between p27^Kip1, GATA3, ATOH1, and POU4F3 Converts Non-sensory Cells to Hair Cells in Adult Mice.

Walters BJ, Coak E, Dearman J, Bailey G, Yamashita T, Kuo B, Zuo J. Walters BJ, et al. Among authors: zuo j. Cell Rep. 2017 Apr 11;19(2):307-320. doi: 10.1016/j.celrep.2017.03.044. Cell Rep. 2017. PMID: 28402854 Free PMC article.

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