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CRISPR/Cas9 somatic multiplex-mutagenesis for high-throughput functional cancer genomics in mice.
Weber J, Öllinger R, Friedrich M, Ehmer U, Barenboim M, Steiger K, Heid I, Mueller S, Maresch R, Engleitner T, Gross N, Geumann U, Fu B, Segler A, Yuan D, Lange S, Strong A, de la Rosa J, Esposito I, Liu P, Cadiñanos J, Vassiliou GS, Schmid RM, Schneider G, Unger K, Yang F, Braren R, Heikenwälder M, Varela I, Saur D, Bradley A, Rad R. Weber J, et al. Among authors: yang f. Proc Natl Acad Sci U S A. 2015 Nov 10;112(45):13982-7. doi: 10.1073/pnas.1512392112. Epub 2015 Oct 27. Proc Natl Acad Sci U S A. 2015. PMID: 26508638 Free PMC article.
Signatures of mutation and selection in the cancer genome.
Bignell GR, Greenman CD, Davies H, Butler AP, Edkins S, Andrews JM, Buck G, Chen L, Beare D, Latimer C, Widaa S, Hinton J, Fahey C, Fu B, Swamy S, Dalgliesh GL, Teh BT, Deloukas P, Yang F, Campbell PJ, Futreal PA, Stratton MR. Bignell GR, et al. Among authors: yang f. Nature. 2010 Feb 18;463(7283):893-8. doi: 10.1038/nature08768. Nature. 2010. PMID: 20164919 Free PMC article.
Massive genomic rearrangement acquired in a single catastrophic event during cancer development.
Stephens PJ, Greenman CD, Fu B, Yang F, Bignell GR, Mudie LJ, Pleasance ED, Lau KW, Beare D, Stebbings LA, McLaren S, Lin ML, McBride DJ, Varela I, Nik-Zainal S, Leroy C, Jia M, Menzies A, Butler AP, Teague JW, Quail MA, Burton J, Swerdlow H, Carter NP, Morsberger LA, Iacobuzio-Donahue C, Follows GA, Green AR, Flanagan AM, Stratton MR, Futreal PA, Campbell PJ. Stephens PJ, et al. Among authors: yang f. Cell. 2011 Jan 7;144(1):27-40. doi: 10.1016/j.cell.2010.11.055. Cell. 2011. PMID: 21215367 Free PMC article.
Estimation of rearrangement phylogeny for cancer genomes.
Greenman CD, Pleasance ED, Newman S, Yang F, Fu B, Nik-Zainal S, Jones D, Lau KW, Carter N, Edwards PA, Futreal PA, Stratton MR, Campbell PJ. Greenman CD, et al. Among authors: yang f. Genome Res. 2012 Feb;22(2):346-61. doi: 10.1101/gr.118414.110. Epub 2011 Oct 12. Genome Res. 2012. PMID: 21994251 Free PMC article.
Massively parallel sequencing reveals the complex structure of an irradiated human chromosome on a mouse background in the Tc1 model of Down syndrome.
Gribble SM, Wiseman FK, Clayton S, Prigmore E, Langley E, Yang F, Maguire S, Fu B, Rajan D, Sheppard O, Scott C, Hauser H, Stephens PJ, Stebbings LA, Ng BL, Fitzgerald T, Quail MA, Banerjee R, Rothkamm K, Tybulewicz VL, Fisher EM, Carter NP. Gribble SM, et al. Among authors: yang f. PLoS One. 2013 Apr 15;8(4):e60482. doi: 10.1371/journal.pone.0060482. Print 2013. PLoS One. 2013. PMID: 23596509 Free PMC article.
Chromosome engineering in zygotes with CRISPR/Cas9.
Boroviak K, Doe B, Banerjee R, Yang F, Bradley A. Boroviak K, et al. Among authors: yang f. Genesis. 2016 Feb;54(2):78-85. doi: 10.1002/dvg.22915. Epub 2016 Jan 25. Genesis. 2016. PMID: 26742453 Free PMC article.
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