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RNA sensing by conventional dendritic cells is central to the development of lupus nephritis.
Celhar T, Hopkins R, Thornhill SI, De Magalhaes R, Hwang SH, Lee HY, Yasuga H, Jones LA, Casco J, Lee B, Thamboo TP, Zhou XJ, Poidinger M, Connolly JE, Wakeland EK, Fairhurst AM. Celhar T, et al. Proc Natl Acad Sci U S A. 2015 Nov 10;112(45):E6195-204. doi: 10.1073/pnas.1507052112. Epub 2015 Oct 28. Proc Natl Acad Sci U S A. 2015. PMID: 26512111 Free PMC article.
The exonuclease Trex1 restrains macrophage proinflammatory activation.
Pereira-Lopes S, Celhar T, Sans-Fons G, Serra M, Fairhurst AM, Lloberas J, Celada A. Pereira-Lopes S, et al. Among authors: celhar t. J Immunol. 2013 Dec 15;191(12):6128-35. doi: 10.4049/jimmunol.1301603. Epub 2013 Nov 11. J Immunol. 2013. PMID: 24218451
TLR7 and TLR9 ligands regulate antigen presentation by macrophages.
Celhar T, Pereira-Lopes S, Thornhill SI, Lee HY, Dhillon MK, Poidinger M, Connolly JE, Lim LH, Biswas SK, Fairhurst AM. Celhar T, et al. Int Immunol. 2016 May;28(5):223-32. doi: 10.1093/intimm/dxv066. Epub 2015 Nov 13. Int Immunol. 2016. PMID: 26567289 Free PMC article.
Pathways leading to an immunological disease: systemic lupus erythematosus.
Zharkova O, Celhar T, Cravens PD, Satterthwaite AB, Fairhurst AM, Davis LS. Zharkova O, et al. Among authors: celhar t. Rheumatology (Oxford). 2017 Apr 1;56(suppl_1):i55-i66. doi: 10.1093/rheumatology/kew427. Rheumatology (Oxford). 2017. PMID: 28375453 Free PMC article. Review.
TLR7 Protein Expression in Mild and Severe Lupus-Prone Models Is Regulated in a Leukocyte, Genetic, and IRAK4 Dependent Manner.
Celhar T, Lu HK, Benso L, Rakhilina L, Lee HY, Tripathi S, Zharkova O, Ong WY, Yasuga H, Au B, Marlier D, Lim LHK, Thamboo TP, Mudgett JS, Mackey MF, Zaller DM, Connolly JE, Fairhurst AM. Celhar T, et al. Front Immunol. 2019 Jul 10;10:1546. doi: 10.3389/fimmu.2019.01546. eCollection 2019. Front Immunol. 2019. PMID: 31354711 Free PMC article.
21 results