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Aminopyrazolo[1,5-a]pyrimidines as potential inhibitors of Mycobacterium tuberculosis: Structure activity relationships and ADME characterization.
Soares de Melo C, Feng TS, van der Westhuyzen R, Gessner RK, Street LJ, Morgans GL, Warner DF, Moosa A, Naran K, Lawrence N, Boshoff HI, Barry CE 3rd, Harris CJ, Gordon R, Chibale K. Soares de Melo C, et al. Among authors: warner df. Bioorg Med Chem. 2015 Nov 15;23(22):7240-50. doi: 10.1016/j.bmc.2015.10.021. Epub 2015 Oct 22. Bioorg Med Chem. 2015. PMID: 26522089
Vitamin B(12) metabolism in Mycobacterium tuberculosis.
Gopinath K, Moosa A, Mizrahi V, Warner DF. Gopinath K, et al. Among authors: warner df. Future Microbiol. 2013 Nov;8(11):1405-18. doi: 10.2217/fmb.13.113. Future Microbiol. 2013. PMID: 24199800 Review.
Synthesis of new verapamil analogues and their evaluation in combination with rifampicin against Mycobacterium tuberculosis and molecular docking studies in the binding site of efflux protein Rv1258c.
Singh K, Kumar M, Pavadai E, Naran K, Warner DF, Ruminski PG, Chibale K. Singh K, et al. Among authors: warner df. Bioorg Med Chem Lett. 2014 Jul 15;24(14):2985-90. doi: 10.1016/j.bmcl.2014.05.022. Epub 2014 May 16. Bioorg Med Chem Lett. 2014. PMID: 24894561
Mycobacterium tuberculosis metabolism.
Warner DF. Warner DF. Cold Spring Harb Perspect Med. 2014 Dec 11;5(4):a021121. doi: 10.1101/cshperspect.a021121. Cold Spring Harb Perspect Med. 2014. PMID: 25502746 Free PMC article. Review.
Pyrrolo[3,4-c]pyridine-1,3(2H)-diones: A Novel Antimycobacterial Class Targeting Mycobacterial Respiration.
van der Westhuyzen R, Winks S, Wilson CR, Boyle GA, Gessner RK, Soares de Melo C, Taylor D, de Kock C, Njoroge M, Brunschwig C, Lawrence N, Rao SP, Sirgel F, van Helden P, Seldon R, Moosa A, Warner DF, Arista L, Manjunatha UH, Smith PW, Street LJ, Chibale K. van der Westhuyzen R, et al. Among authors: warner df. J Med Chem. 2015 Dec 10;58(23):9371-81. doi: 10.1021/acs.jmedchem.5b01542. Epub 2015 Nov 20. J Med Chem. 2015. PMID: 26551248
177 results