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Page 1
Contrasting genetic architectures of schizophrenia and other complex diseases using fast variance-components analysis.
Loh PR, Bhatia G, Gusev A, Finucane HK, Bulik-Sullivan BK, Pollack SJ; Schizophrenia Working Group of Psychiatric Genomics Consortium; de Candia TR, Lee SH, Wray NR, Kendler KS, O'Donovan MC, Neale BM, Patterson N, Price AL. Loh PR, et al. Among authors: de candia tr. Nat Genet. 2015 Dec;47(12):1385-92. doi: 10.1038/ng.3431. Epub 2015 Nov 2. Nat Genet. 2015. PMID: 26523775 Free PMC article.
Estimating the proportion of variation in susceptibility to schizophrenia captured by common SNPs.
Lee SH, DeCandia TR, Ripke S, Yang J; Schizophrenia Psychiatric Genome-Wide Association Study Consortium (PGC-SCZ); International Schizophrenia Consortium (ISC); Molecular Genetics of Schizophrenia Collaboration (MGS); Sullivan PF, Goddard ME, Keller MC, Visscher PM, Wray NR. Lee SH, et al. Nat Genet. 2012 Feb 19;44(3):247-50. doi: 10.1038/ng.1108. Nat Genet. 2012. PMID: 22344220 Free PMC article.
Additive genetic variation in schizophrenia risk is shared by populations of African and European descent.
de Candia TR, Lee SH, Yang J, Browning BL, Gejman PV, Levinson DF, Mowry BJ, Hewitt JK, Goddard ME, O'Donovan MC, Purcell SM, Posthuma D; International Schizophrenia Consortium; Molecular Genetics of Schizophrenia Collaboration; Visscher PM, Wray NR, Keller MC. de Candia TR, et al. Am J Hum Genet. 2013 Sep 5;93(3):463-70. doi: 10.1016/j.ajhg.2013.07.007. Epub 2013 Aug 15. Am J Hum Genet. 2013. PMID: 23954163 Free PMC article.
Comparison of methods that use whole genome data to estimate the heritability and genetic architecture of complex traits.
Evans LM, Tahmasbi R, Vrieze SI, Abecasis GR, Das S, Gazal S, Bjelland DW, de Candia TR; Haplotype Reference Consortium; Goddard ME, Neale BM, Yang J, Visscher PM, Keller MC. Evans LM, et al. Among authors: de candia tr. Nat Genet. 2018 May;50(5):737-745. doi: 10.1038/s41588-018-0108-x. Epub 2018 Apr 26. Nat Genet. 2018. PMID: 29700474 Free PMC article.
Assortative mating biases marker-based heritability estimators.
Border R, O'Rourke S, de Candia T, Goddard ME, Visscher PM, Yengo L, Jones M, Keller MC. Border R, et al. Nat Commun. 2022 Feb 3;13(1):660. doi: 10.1038/s41467-022-28294-9. Nat Commun. 2022. PMID: 35115518 Free PMC article.
Meta-analysis of Positive and Negative Symptoms Reveals Schizophrenia Modifier Genes.
Edwards AC, Bigdeli TB, Docherty AR, Bacanu S, Lee D, de Candia TR, Moscati A, Thiselton DL, Maher BS, Wormley BK; Molecular Genetics of Schizophrenia Collaboration (MGS); Walsh D, O'Neill FA, Kendler KS, Riley BP, Fanous AH. Edwards AC, et al. Among authors: de candia tr. Schizophr Bull. 2016 Mar;42(2):279-87. doi: 10.1093/schbul/sbv119. Epub 2015 Aug 27. Schizophr Bull. 2016. PMID: 26316594 Free PMC article.
Narrow-sense heritability estimation of complex traits using identity-by-descent information.
Evans LM, Tahmasbi R, Jones M, Vrieze SI, Abecasis GR, Das S, Bjelland DW, de Candia TR, Yang J, Goddard ME, Visscher PM, Keller MC; Haplotype Reference Consortium. Evans LM, et al. Among authors: de candia tr. Heredity (Edinb). 2018 Dec;121(6):616-630. doi: 10.1038/s41437-018-0067-0. Epub 2018 Mar 28. Heredity (Edinb). 2018. PMID: 29588506 Free PMC article.
Evolutionary behavioral genetics.
Zietsch BP, de Candia TR, Keller MC. Zietsch BP, et al. Among authors: de candia tr. Curr Opin Behav Sci. 2015 Apr;2:73-80. doi: 10.1016/j.cobeha.2014.09.005. Curr Opin Behav Sci. 2015. PMID: 25587556 Free PMC article.