Hyman BT - Search Results

1

Removing endogenous tau does not prevent tau propagation yet reduces its neurotoxicity.

Wegmann S, Maury EA, Kirk MJ, Saqran L, Roe A, DeVos SL, Nicholls S, Fan Z, Takeda S, Cagsal-Getkin O, William CM, Spires-Jones TL, Pitstick R, Carlson GA, Pooler AM, Hyman BT. Wegmann S, et al. Among authors: hyman bt. EMBO J. 2015 Dec 14;34(24):3028-41. doi: 10.15252/embj.201592748. Epub 2015 Nov 4. EMBO J. 2015. PMID: 26538322 Free PMC article.

2

Specific tau phosphorylation sites correlate with severity of neuronal cytopathology in Alzheimer's disease.

Augustinack JC, Schneider A, Mandelkow EM, Hyman BT. Augustinack JC, et al. Among authors: hyman bt. Acta Neuropathol. 2002 Jan;103(1):26-35. doi: 10.1007/s004010100423. Acta Neuropathol. 2002. PMID: 11837744

3

Transcriptional and conformational changes of the tau molecule in Alzheimer's disease.

Hyman BT, Augustinack JC, Ingelsson M. Hyman BT, et al. Biochim Biophys Acta. 2005 Jan 3;1739(2-3):150-7. doi: 10.1016/j.bbadis.2004.06.015. Biochim Biophys Acta. 2005. PMID: 15615634 Free article. Review.

4

Region-specific dissociation of neuronal loss and neurofibrillary pathology in a mouse model of tauopathy.

Spires TL, Orne JD, SantaCruz K, Pitstick R, Carlson GA, Ashe KH, Hyman BT. Spires TL, et al. Among authors: hyman bt. Am J Pathol. 2006 May;168(5):1598-607. doi: 10.2353/ajpath.2006.050840. Am J Pathol. 2006. PMID: 16651626 Free PMC article.

5

Impaired spine stability underlies plaque-related spine loss in an Alzheimer's disease mouse model.

Spires-Jones TL, Meyer-Luehmann M, Osetek JD, Jones PB, Stern EA, Bacskai BJ, Hyman BT. Spires-Jones TL, et al. Among authors: hyman bt. Am J Pathol. 2007 Oct;171(4):1304-11. doi: 10.2353/ajpath.2007.070055. Epub 2007 Aug 23. Am J Pathol. 2007. PMID: 17717139 Free PMC article.

6

TAR-DNA binding protein 43 in Pick disease.

Freeman SH, Spires-Jones T, Hyman BT, Growdon JH, Frosch MP. Freeman SH, et al. Among authors: hyman bt. J Neuropathol Exp Neurol. 2008 Jan;67(1):62-7. doi: 10.1097/nen.0b013e3181609361. J Neuropathol Exp Neurol. 2008. PMID: 18091558

7

In vivo imaging reveals dissociation between caspase activation and acute neuronal death in tangle-bearing neurons.

Spires-Jones TL, de Calignon A, Matsui T, Zehr C, Pitstick R, Wu HY, Osetek JD, Jones PB, Bacskai BJ, Feany MB, Carlson GA, Ashe KH, Lewis J, Hyman BT. Spires-Jones TL, et al. Among authors: hyman bt. J Neurosci. 2008 Jan 23;28(4):862-7. doi: 10.1523/JNEUROSCI.3072-08.2008. J Neurosci. 2008. PMID: 18216194 Free PMC article.

8

Rapid appearance and local toxicity of amyloid-beta plaques in a mouse model of Alzheimer's disease.

Meyer-Luehmann M, Spires-Jones TL, Prada C, Garcia-Alloza M, de Calignon A, Rozkalne A, Koenigsknecht-Talboo J, Holtzman DM, Bacskai BJ, Hyman BT. Meyer-Luehmann M, et al. Among authors: hyman bt. Nature. 2008 Feb 7;451(7179):720-4. doi: 10.1038/nature06616. Nature. 2008. PMID: 18256671 Free PMC article.

9

Two postprocessing techniques for the elimination of background autofluorescence for fluorescence lifetime imaging microscopy.

Jones PB, Rozkalne A, Meyer-Luehmann M, Spires-Jones TL, Makarova A, Kumar AT, Berezovska O, Bacskai BB, Hyman BT. Jones PB, et al. Among authors: hyman bt. J Biomed Opt. 2008 Jan-Feb;13(1):014008. doi: 10.1117/1.2837169. J Biomed Opt. 2008. PMID: 18315366 Free article.

10

Passive immunotherapy rapidly increases structural plasticity in a mouse model of Alzheimer disease.

Spires-Jones TL, Mielke ML, Rozkalne A, Meyer-Luehmann M, de Calignon A, Bacskai BJ, Schenk D, Hyman BT. Spires-Jones TL, et al. Among authors: hyman bt. Neurobiol Dis. 2009 Feb;33(2):213-20. doi: 10.1016/j.nbd.2008.10.011. Epub 2008 Nov 6. Neurobiol Dis. 2009. PMID: 19028582 Free PMC article.

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