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Huntingtin functions as a scaffold for selective macroautophagy.
Rui YN, Xu Z, Patel B, Chen Z, Chen D, Tito A, David G, Sun Y, Stimming EF, Bellen HJ, Cuervo AM, Zhang S. Rui YN, et al. Among authors: xu z. Nat Cell Biol. 2015 Mar;17(3):262-75. doi: 10.1038/ncb3101. Epub 2015 Feb 16. Nat Cell Biol. 2015. PMID: 25686248 Free PMC article.
Studying polyglutamine diseases in Drosophila.
Xu Z, Tito AJ, Rui YN, Zhang S. Xu Z, et al. Exp Neurol. 2015 Dec;274(Pt A):25-41. doi: 10.1016/j.expneurol.2015.08.002. Epub 2015 Aug 6. Exp Neurol. 2015. PMID: 26257024 Free PMC article. Review.
HAP40 is a conserved central regulator of Huntingtin and a potential modulator of Huntington's disease pathogenesis.
Xu S, Li G, Ye X, Chen D, Chen Z, Xu Z, Daniele M, Tambone S, Ceccacci A, Tomei L, Ye L, Yu Y, Solbach A, Farmer SM, Stimming EF, McAllister G, Marchionini DM, Zhang S. Xu S, et al. Among authors: xu z. PLoS Genet. 2022 Jul 19;18(7):e1010302. doi: 10.1371/journal.pgen.1010302. eCollection 2022 Jul. PLoS Genet. 2022. PMID: 35853002 Free PMC article.
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