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Basic chemokine-derived glycosaminoglycan binding peptides exert antiviral properties against dengue virus serotype 2, herpes simplex virus-1 and respiratory syncytial virus.
Vanheule V, Vervaeke P, Mortier A, Noppen S, Gouwy M, Snoeck R, Andrei G, Van Damme J, Liekens S, Proost P. Vanheule V, et al. Among authors: liekens s. Biochem Pharmacol. 2016 Jan 15;100:73-85. doi: 10.1016/j.bcp.2015.11.001. Epub 2015 Nov 10. Biochem Pharmacol. 2016. PMID: 26551597 Free article.
Endothelial dysfunction in dengue virus pathology.
Vervaeke P, Vermeire K, Liekens S. Vervaeke P, et al. Among authors: liekens s. Rev Med Virol. 2015 Jan;25(1):50-67. doi: 10.1002/rmv.1818. Epub 2014 Nov 27. Rev Med Virol. 2015. PMID: 25430853 Review.
Truncation of CXCL12 by CD26 reduces its CXC chemokine receptor 4- and atypical chemokine receptor 3-dependent activity on endothelial cells and lymphocytes.
Janssens R, Mortier A, Boff D, Ruytinx P, Gouwy M, Vantilt B, Larsen O, Daugvilaite V, Rosenkilde MM, Parmentier M, Noppen S, Liekens S, Van Damme J, Struyf S, Teixeira MM, Amaral FA, Proost P. Janssens R, et al. Among authors: liekens s. Biochem Pharmacol. 2017 May 15;132:92-101. doi: 10.1016/j.bcp.2017.03.009. Epub 2017 Mar 18. Biochem Pharmacol. 2017. PMID: 28322746
Peroxynitrite Exposure of CXCL12 Impairs Monocyte, Lymphocyte and Endothelial Cell Chemotaxis, Lymphocyte Extravasation in vivo and Anti-HIV-1 Activity.
Janssens R, Boff D, Ruytinx P, Mortier A, Vanheule V, Larsen O, Daugvilaite V, Rosenkilde MM, Noppen S, Liekens S, Schols D, De Meester I, Opdenakker G, Struyf S, Teixeira MM, Amaral FA, Proost P. Janssens R, et al. Among authors: liekens s. Front Immunol. 2018 Aug 28;9:1933. doi: 10.3389/fimmu.2018.01933. eCollection 2018. Front Immunol. 2018. PMID: 30233568 Free PMC article.
A multi-targeted drug candidate with dual anti-HIV and anti-HSV activity.
Balzarini J, Andrei G, Balestra E, Huskens D, Vanpouille C, Introini A, Zicari S, Liekens S, Snoeck R, Holý A, Perno CF, Margolis L, Schols D. Balzarini J, et al. Among authors: liekens s. PLoS Pathog. 2013;9(7):e1003456. doi: 10.1371/journal.ppat.1003456. Epub 2013 Jul 25. PLoS Pathog. 2013. PMID: 23935482 Free PMC article.
142 results