Loughran P - Search Results

1

Platelet-derived HMGB1 is a critical mediator of thrombosis.

Vogel S, Bodenstein R, Chen Q, Feil S, Feil R, Rheinlaender J, Schäffer TE, Bohn E, Frick JS, Borst O, Münzer P, Walker B, Markel J, Csanyi G, Pagano PJ, Loughran P, Jessup ME, Watkins SC, Bullock GC, Sperry JL, Zuckerbraun BS, Billiar TR, Lotze MT, Gawaz M, Neal MD. Vogel S, et al. Among authors: loughran p. J Clin Invest. 2015 Dec;125(12):4638-54. doi: 10.1172/JCI81660. Epub 2015 Nov 9. J Clin Invest. 2015. PMID: 26551681 Free PMC article.

2

Monomeric inducible nitric oxide synthase localizes to peroxisomes in hepatocytes.

Loughran PA, Stolz DB, Vodovotz Y, Watkins SC, Simmons RL, Billiar TR. Loughran PA, et al. Proc Natl Acad Sci U S A. 2005 Sep 27;102(39):13837-42. doi: 10.1073/pnas.0503926102. Epub 2005 Sep 19. Proc Natl Acad Sci U S A. 2005. PMID: 16172396 Free PMC article.

3

Carbon monoxide protects hepatocytes from TNF-alpha/Actinomycin D by inhibition of the caspase-8-mediated apoptotic pathway.

Kim HS, Loughran PA, Kim PK, Billiar TR, Zuckerbraun BS. Kim HS, et al. Biochem Biophys Res Commun. 2006 Jun 16;344(4):1172-8. doi: 10.1016/j.bbrc.2006.03.180. Epub 2006 Apr 6. Biochem Biophys Res Commun. 2006. PMID: 16647044

4

Carbon monoxide decreases the level of iNOS protein and active dimer in IL-1beta-stimulated hepatocytes.

Kim HS, Loughran PA, Billiar TR. Kim HS, et al. Nitric Oxide. 2008 Jun;18(4):256-65. doi: 10.1016/j.niox.2008.02.002. Epub 2008 Feb 15. Nitric Oxide. 2008. PMID: 18313411 Free PMC article.

5

Carbon monoxide activates NF-kappaB via ROS generation and Akt pathways to protect against cell death of hepatocytes.

Kim HS, Loughran PA, Rao J, Billiar TR, Zuckerbraun BS. Kim HS, et al. Am J Physiol Gastrointest Liver Physiol. 2008 Jul;295(1):G146-G152. doi: 10.1152/ajpgi.00105.2007. Epub 2008 May 22. Am J Physiol Gastrointest Liver Physiol. 2008. PMID: 18497334 Free article.

6

Systemic inflammation and liver injury following hemorrhagic shock and peripheral tissue trauma involve functional TLR9 signaling on bone marrow-derived cells and parenchymal cells.

Gill R, Ruan X, Menzel CL, Namkoong S, Loughran P, Hackam DJ, Billiar TR. Gill R, et al. Among authors: loughran p. Shock. 2011 Feb;35(2):164-70. doi: 10.1097/SHK.0b013e3181eddcab. Shock. 2011. PMID: 20577143 Free PMC article.

7

Endogenous HMGB1 regulates autophagy.

Tang D, Kang R, Livesey KM, Cheh CW, Farkas A, Loughran P, Hoppe G, Bianchi ME, Tracey KJ, Zeh HJ 3rd, Lotze MT. Tang D, et al. Among authors: loughran p. J Cell Biol. 2010 Sep 6;190(5):881-92. doi: 10.1083/jcb.200911078. J Cell Biol. 2010. PMID: 20819940 Free PMC article.

8

Heme oxygenase-1-mediated autophagy protects against hepatocyte cell death and hepatic injury from infection/sepsis in mice.

Carchman EH, Rao J, Loughran PA, Rosengart MR, Zuckerbraun BS. Carchman EH, et al. Hepatology. 2011 Jun;53(6):2053-62. doi: 10.1002/hep.24324. Epub 2011 May 2. Hepatology. 2011. PMID: 21437926 Free PMC article.

9

Caspase-1 is hepatoprotective during trauma and hemorrhagic shock by reducing liver injury and inflammation.

Menzel CL, Sun Q, Loughran PA, Pape HC, Billiar TR, Scott MJ. Menzel CL, et al. Mol Med. 2011 Sep-Oct;17(9-10):1031-8. doi: 10.2119/molmed.2011.00015. Epub 2011 Jun 7. Mol Med. 2011. PMID: 21666957 Free PMC article.

10

Mast cells play a critical role in the systemic inflammatory response and end-organ injury resulting from trauma.

Cai C, Cao Z, Loughran PA, Kim S, Darwiche S, Korff S, Billiar TR. Cai C, et al. J Am Coll Surg. 2011 Nov;213(5):604-15. doi: 10.1016/j.jamcollsurg.2011.08.009. Epub 2011 Sep 14. J Am Coll Surg. 2011. PMID: 21920785 Free PMC article.

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