Ohba K - Search Results

1

Thyroid Hormone Stimulation of Autophagy Is Essential for Mitochondrial Biogenesis and Activity in Skeletal Muscle.

Lesmana R, Sinha RA, Singh BK, Zhou J, Ohba K, Wu Y, Yau WW, Bay BH, Yen PM. Lesmana R, et al. Among authors: ohba k. Endocrinology. 2016 Jan;157(1):23-38. doi: 10.1210/en.2015-1632. Epub 2015 Nov 12. Endocrinology. 2016. PMID: 26562261

2

Role of thyroid hormone in hepatic gene regulation, chromatin remodeling, and autophagy.

Singh BK, Sinha RA, Ohba K, Yen PM. Singh BK, et al. Among authors: ohba k. Mol Cell Endocrinol. 2017 Dec 15;458:160-168. doi: 10.1016/j.mce.2017.02.018. Epub 2017 Feb 16. Mol Cell Endocrinol. 2017. PMID: 28216439 Review.

3

Thyroid hormone receptor and ERRα coordinately regulate mitochondrial fission, mitophagy, biogenesis, and function.

Singh BK, Sinha RA, Tripathi M, Mendoza A, Ohba K, Sy JAC, Xie SY, Zhou J, Ho JP, Chang CY, Wu Y, Giguère V, Bay BH, Vanacker JM, Ghosh S, Gauthier K, Hollenberg AN, McDonnell DP, Yen PM. Singh BK, et al. Among authors: ohba k. Sci Signal. 2018 Jun 26;11(536):eaam5855. doi: 10.1126/scisignal.aam5855. Sci Signal. 2018. PMID: 29945885

4

Thyroid hormone induction of mitochondrial activity is coupled to mitophagy via ROS-AMPK-ULK1 signaling.

Sinha RA, Singh BK, Zhou J, Wu Y, Farah BL, Ohba K, Lesmana R, Gooding J, Bay BH, Yen PM. Sinha RA, et al. Among authors: ohba k. Autophagy. 2015;11(8):1341-57. doi: 10.1080/15548627.2015.1061849. Autophagy. 2015. PMID: 26103054 Free PMC article.

5

Desensitization and Incomplete Recovery of Hepatic Target Genes After Chronic Thyroid Hormone Treatment and Withdrawal in Male Adult Mice.

Ohba K, Leow MK, Singh BK, Sinha RA, Lesmana R, Liao XH, Ghosh S, Refetoff S, Sng JC, Yen PM. Ohba K, et al. Endocrinology. 2016 Apr;157(4):1660-72. doi: 10.1210/en.2015-1848. Epub 2016 Feb 11. Endocrinology. 2016. PMID: 26866609 Free PMC article.

6

Changes in Hepatic TRβ Protein Expression, Lipogenic Gene Expression, and Long-Chain Acylcarnitine Levels During Chronic Hyperthyroidism and Triiodothyronine Withdrawal in a Mouse Model.

Ohba K, Sinha RA, Singh BK, Iannucci LF, Zhou J, Kovalik JP, Liao XH, Refetoff S, Sng JCG, Leow MK, Yen PM. Ohba K, et al. Thyroid. 2017 Jun;27(6):852-860. doi: 10.1089/thy.2016.0456. Epub 2017 May 24. Thyroid. 2017. PMID: 28457184 Free PMC article.

7

MED1 mediator subunit is a key regulator of hepatic autophagy and lipid metabolism.

Zhou J, Singh BK, Ho JP, Lim A, Bruinstroop E, Ohba K, Sinha RA, Yen PM. Zhou J, et al. Among authors: ohba k. Autophagy. 2021 Dec;17(12):4043-4061. doi: 10.1080/15548627.2021.1899691. Epub 2021 Mar 18. Autophagy. 2021. PMID: 33734012 Free PMC article.

8

Hepatic FOXO1 Target Genes Are Co-regulated by Thyroid Hormone via RICTOR Protein Deacetylation and MTORC2-AKT Protein Inhibition.

Singh BK, Sinha RA, Zhou J, Tripathi M, Ohba K, Wang ME, Astapova I, Ghosh S, Hollenberg AN, Gauthier K, Yen PM. Singh BK, et al. Among authors: ohba k. J Biol Chem. 2016 Jan 1;291(1):198-214. doi: 10.1074/jbc.M115.668673. Epub 2015 Oct 9. J Biol Chem. 2016. PMID: 26453307 Free PMC article.

9

Loss of ULK1 increases RPS6KB1-NCOR1 repression of NR1H/LXR-mediated Scd1 transcription and augments lipotoxicity in hepatic cells.

Sinha RA, Singh BK, Zhou J, Xie S, Farah BL, Lesmana R, Ohba K, Tripathi M, Ghosh S, Hollenberg AN, Yen PM. Sinha RA, et al. Among authors: ohba k. Autophagy. 2017 Jan 2;13(1):169-186. doi: 10.1080/15548627.2016.1235123. Epub 2016 Nov 15. Autophagy. 2017. PMID: 27846372 Free PMC article.

10

Inhibition of GATA2-dependent transactivation of the TSHbeta gene by ligand-bound estrogen receptor alpha.

Nagayama K, Sasaki S, Matsushita A, Ohba K, Iwaki H, Matsunaga H, Suzuki S, Misawa H, Ishizuka K, Oki Y, Noh JY, Nakamura H. Nagayama K, et al. Among authors: ohba k. J Endocrinol. 2008 Oct;199(1):113-25. doi: 10.1677/JOE-08-0128. Epub 2008 Jul 24. J Endocrinol. 2008. PMID: 18653622

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