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SCRaMbLE generates designed combinatorial stochastic diversity in synthetic chromosomes.
Shen Y, Stracquadanio G, Wang Y, Yang K, Mitchell LA, Xue Y, Cai Y, Chen T, Dymond JS, Kang K, Gong J, Zeng X, Zhang Y, Li Y, Feng Q, Xu X, Wang J, Wang J, Yang H, Boeke JD, Bader JS. Shen Y, et al. Among authors: gong j. Genome Res. 2016 Jan;26(1):36-49. doi: 10.1101/gr.193433.115. Epub 2015 Nov 13. Genome Res. 2016. PMID: 26566658 Free PMC article.
Engineering the ribosomal DNA in a megabase synthetic chromosome.
Zhang W, Zhao G, Luo Z, Lin Y, Wang L, Guo Y, Wang A, Jiang S, Jiang Q, Gong J, Wang Y, Hou S, Huang J, Li T, Qin Y, Dong J, Qin Q, Zhang J, Zou X, He X, Zhao L, Xiao Y, Xu M, Cheng E, Huang N, Zhou T, Shen Y, Walker R, Luo Y, Kuang Z, Mitchell LA, Yang K, Richardson SM, Wu Y, Li BZ, Yuan YJ, Yang H, Lin J, Chen GQ, Wu Q, Bader JS, Cai Y, Boeke JD, Dai J. Zhang W, et al. Among authors: gong j. Science. 2017 Mar 10;355(6329):eaaf3981. doi: 10.1126/science.aaf3981. Science. 2017. PMID: 28280149
Deep functional analysis of synII, a 770-kilobase synthetic yeast chromosome.
Shen Y, Wang Y, Chen T, Gao F, Gong J, Abramczyk D, Walker R, Zhao H, Chen S, Liu W, Luo Y, Müller CA, Paul-Dubois-Taine A, Alver B, Stracquadanio G, Mitchell LA, Luo Z, Fan Y, Zhou B, Wen B, Tan F, Wang Y, Zi J, Xie Z, Li B, Yang K, Richardson SM, Jiang H, French CE, Nieduszynski CA, Koszul R, Marston AL, Yuan Y, Wang J, Bader JS, Dai J, Boeke JD, Xu X, Cai Y, Yang H. Shen Y, et al. Among authors: gong j. Science. 2017 Mar 10;355(6329):eaaf4791. doi: 10.1126/science.aaf4791. Science. 2017. PMID: 28280153 Free PMC article.
Dissecting aneuploidy phenotypes by constructing Sc2.0 chromosome VII and SCRaMbLEing synthetic disomic yeast.
Shen Y, Gao F, Wang Y, Wang Y, Zheng J, Gong J, Zhang J, Luo Z, Schindler D, Deng Y, Ding W, Lin T, Swidah R, Zhao H, Jiang S, Zeng C, Chen S, Chen T, Wang Y, Luo Y, Mitchell L, Bader JS, Zhang G, Shen X, Wang J, Fu X, Dai J, Boeke JD, Yang H, Xu X, Cai Y. Shen Y, et al. Among authors: gong j. Cell Genom. 2023 Nov 9;3(11):100364. doi: 10.1016/j.xgen.2023.100364. eCollection 2023 Nov 8. Cell Genom. 2023. PMID: 38020968 Free PMC article.
Limitations of gene editing assessments in human preimplantation embryos.
Liang D, Mikhalchenko A, Ma H, Marti Gutierrez N, Chen T, Lee Y, Park SW, Tippner-Hedges R, Koski A, Darby H, Li Y, Van Dyken C, Zhao H, Wu K, Zhang J, Hou Z, So S, Han J, Park J, Kim CJ, Zong K, Gong J, Yuan Y, Gu Y, Shen Y, Olson SB, Yang H, Battaglia D, O'Leary T, Krieg SA, Lee DM, Wu DH, Duell PB, Kaul S, Kim JS, Heitner SB, Kang E, Chen ZJ, Amato P, Mitalipov S. Liang D, et al. Among authors: gong j. Nat Commun. 2023 Mar 7;14(1):1219. doi: 10.1038/s41467-023-36820-6. Nat Commun. 2023. PMID: 36882397 Free PMC article.
8,243 results