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433 results

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Therapeutic antibodies reveal Notch control of transdifferentiation in the adult lung.
Lafkas D, Shelton A, Chiu C, de Leon Boenig G, Chen Y, Stawicki SS, Siltanen C, Reichelt M, Zhou M, Wu X, Eastham-Anderson J, Moore H, Roose-Girma M, Chinn Y, Hang JQ, Warming S, Egen J, Lee WP, Austin C, Wu Y, Payandeh J, Lowe JB, Siebel CW. Lafkas D, et al. Among authors: shelton a. Nature. 2015 Dec 3;528(7580):127-31. doi: 10.1038/nature15715. Epub 2015 Nov 18. Nature. 2015. PMID: 26580007
Therapeutic antibody targeting of individual Notch receptors.
Wu Y, Cain-Hom C, Choy L, Hagenbeek TJ, de Leon GP, Chen Y, Finkle D, Venook R, Wu X, Ridgway J, Schahin-Reed D, Dow GJ, Shelton A, Stawicki S, Watts RJ, Zhang J, Choy R, Howard P, Kadyk L, Yan M, Zha J, Callahan CA, Hymowitz SG, Siebel CW. Wu Y, et al. Among authors: shelton a. Nature. 2010 Apr 15;464(7291):1052-7. doi: 10.1038/nature08878. Nature. 2010. PMID: 20393564
Manic Fringe deficiency imposes Jagged1 addiction to intestinal tumor cells.
López-Arribillaga E, Rodilla V, Colomer C, Vert A, Shelton A, Cheng JH, Yan B, Gonzalez-Perez A, Junttila MR, Iglesias M, Torres F, Albanell J, Villanueva A, Bigas A, Siebel CW, Espinosa L. López-Arribillaga E, et al. Among authors: shelton a. Nat Commun. 2018 Jul 31;9(1):2992. doi: 10.1038/s41467-018-05385-0. Nat Commun. 2018. PMID: 30065304 Free PMC article.
Transient blockade of delta-like Notch ligands prevents allograft rejection mediated by cellular and humoral mechanisms in a mouse model of heart transplantation.
Wood S, Feng J, Chung J, Radojcic V, Sandy-Sloat AR, Friedman A, Shelton A, Yan M, Siebel CW, Bishop DK, Maillard I. Wood S, et al. Among authors: shelton a. J Immunol. 2015 Mar 15;194(6):2899-908. doi: 10.4049/jimmunol.1402034. Epub 2015 Feb 16. J Immunol. 2015. PMID: 25687759 Free PMC article.
Constitutive NOTCH3 Signaling Promotes the Growth of Basal Breast Cancers.
Choy L, Hagenbeek TJ, Solon M, French D, Finkle D, Shelton A, Venook R, Brauer MJ, Siebel CW. Choy L, et al. Among authors: shelton a. Cancer Res. 2017 Mar 15;77(6):1439-1452. doi: 10.1158/0008-5472.CAN-16-1022. Epub 2017 Jan 20. Cancer Res. 2017. PMID: 28108512
Blockade of individual Notch ligands and receptors controls graft-versus-host disease.
Tran IT, Sandy AR, Carulli AJ, Ebens C, Chung J, Shan GT, Radojcic V, Friedman A, Gridley T, Shelton A, Reddy P, Samuelson LC, Yan M, Siebel CW, Maillard I. Tran IT, et al. Among authors: shelton a. J Clin Invest. 2013 Apr;123(4):1590-604. doi: 10.1172/JCI65477. J Clin Invest. 2013. PMID: 23454750 Free PMC article.
Screening, Recruitment, and Baseline Characteristics for the Strategies to Reduce Injuries and Develop Confidence in Elders (STRIDE) Study.
Gill TM, McGloin JM, Latham NK, Charpentier PA, Araujo KL, Skokos EA, Lu C, Shelton A, Bhasin S, Bianco LM, Carnie MB, Covinsky KE, Dykes P, Esserman DA, Ganz DA, Gurwitz JH, Hanson C, Nyquist LV, Reuben DB, Wallace RB, Greene EJ. Gill TM, et al. Among authors: shelton a. J Gerontol A Biol Sci Med Sci. 2018 Oct 8;73(11):1495-1501. doi: 10.1093/gerona/gly076. J Gerontol A Biol Sci Med Sci. 2018. PMID: 30020415 Free PMC article.
Optimizing Retention in a Pragmatic Trial of Community-Living Older Persons: The STRIDE Study.
Gill TM, McGloin JM, Shelton A, Bianco LM, Skokos EA, Latham NK, Ganz DA, Nyquist LV, Wallace RB, Carnie MB, Dykes PC, Goehring LA, Doyle M, Charpentier PA, Greene EJ, Araujo KL. Gill TM, et al. Among authors: shelton a. J Am Geriatr Soc. 2020 Jun;68(6):1242-1249. doi: 10.1111/jgs.16356. Epub 2020 Mar 25. J Am Geriatr Soc. 2020. PMID: 32212395 Free PMC article. Clinical Trial.
Protocol for serious fall injury adjudication in the Strategies to Reduce Injuries and Develop Confidence in Elders (STRIDE) study.
Ganz DA, Siu AL, Magaziner J, Latham NK, Travison TG, Lorenze NP, Lu C, Wang R, Greene EJ, Stowe CL, Harvin LN, Araujo KLB, Gurwitz JH, Agrawal Y, Correa-De-Araujo R, Peduzzi P, Gill TM; STRIDE Investigators. Ganz DA, et al. Inj Epidemiol. 2019 Apr 15;6:14. doi: 10.1186/s40621-019-0190-2. eCollection 2019. Inj Epidemiol. 2019. PMID: 31245263 Free PMC article.
433 results