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Page 1
Epigenetic programming of monocyte-to-macrophage differentiation and trained innate immunity.
Saeed S, Quintin J, Kerstens HH, Rao NA, Aghajanirefah A, Matarese F, Cheng SC, Ratter J, Berentsen K, van der Ent MA, Sharifi N, Janssen-Megens EM, Ter Huurne M, Mandoli A, van Schaik T, Ng A, Burden F, Downes K, Frontini M, Kumar V, Giamarellos-Bourboulis EJ, Ouwehand WH, van der Meer JW, Joosten LA, Wijmenga C, Martens JH, Xavier RJ, Logie C, Netea MG, Stunnenberg HG. Saeed S, et al. Science. 2014 Sep 26;345(6204):1251086. doi: 10.1126/science.1251086. Science. 2014. PMID: 25258085 Free PMC article.
β-Glucan Reverses the Epigenetic State of LPS-Induced Immunological Tolerance.
Novakovic B, Habibi E, Wang SY, Arts RJW, Davar R, Megchelenbrink W, Kim B, Kuznetsova T, Kox M, Zwaag J, Matarese F, van Heeringen SJ, Janssen-Megens EM, Sharifi N, Wang C, Keramati F, Schoonenberg V, Flicek P, Clarke L, Pickkers P, Heath S, Gut I, Netea MG, Martens JHA, Logie C, Stunnenberg HG. Novakovic B, et al. Among authors: janssen megens em. Cell. 2016 Nov 17;167(5):1354-1368.e14. doi: 10.1016/j.cell.2016.09.034. Cell. 2016. PMID: 27863248 Free PMC article.
Role of p53 serine 46 in p53 target gene regulation.
Smeenk L, van Heeringen SJ, Koeppel M, Gilbert B, Janssen-Megens E, Stunnenberg HG, Lohrum M. Smeenk L, et al. PLoS One. 2011 Mar 4;6(3):e17574. doi: 10.1371/journal.pone.0017574. PLoS One. 2011. PMID: 21394211 Free PMC article.
The Hematopoietic Transcription Factors RUNX1 and ERG Prevent AML1-ETO Oncogene Overexpression and Onset of the Apoptosis Program in t(8;21) AMLs.
Mandoli A, Singh AA, Prange KHM, Tijchon E, Oerlemans M, Dirks R, Ter Huurne M, Wierenga ATJ, Janssen-Megens EM, Berentsen K, Sharifi N, Kim B, Matarese F, Nguyen LN, Hubner NC, Rao NA, van den Akker E, Altucci L, Vellenga E, Stunnenberg HG, Martens JHA. Mandoli A, et al. Among authors: janssen megens em. Cell Rep. 2016 Nov 15;17(8):2087-2100. doi: 10.1016/j.celrep.2016.08.082. Cell Rep. 2016. PMID: 27851970 Free article.
Blueprint of human thymopoiesis reveals molecular mechanisms of stage-specific TCR enhancer activation.
Cieslak A, Charbonnier G, Tesio M, Mathieu EL, Belhocine M, Touzart A, Smith C, Hypolite G, Andrieu GP, Martens JHA, Janssen-Megens E, Gut M, Gut I, Boissel N, Petit A, Puthier D, Macintyre E, Stunnenberg HG, Spicuglia S, Asnafi V. Cieslak A, et al. J Exp Med. 2020 Sep 7;217(9):e20192360. doi: 10.1084/jem.20192360. J Exp Med. 2020. PMID: 32667968 Free PMC article.
Dendritic Cells Actively Limit Interleukin-10 Production Under Inflammatory Conditions via DC-SCRIPT and Dual-Specificity Phosphatase 4.
Søndergaard JN, van Heeringen SJ, Looman MWG, Tang C, Triantis V, Louche P, Janssen-Megens EM, Sieuwerts AM, Martens JWM, Logie C, Stunnenberg HG, Ansems M, Adema GJ. Søndergaard JN, et al. Among authors: janssen megens em. Front Immunol. 2018 Jun 22;9:1420. doi: 10.3389/fimmu.2018.01420. eCollection 2018. Front Immunol. 2018. PMID: 29988341 Free PMC article.
The acute myeloid leukemia associated AML1-ETO fusion protein alters the transcriptome and cellular progression in a single-oncogene expressing in vitro induced pluripotent stem cell based granulocyte differentiation model.
Tijchon E, Yi G, Mandoli A, Smits JGA, Ferrari F, Heuts BMH, Wijnen F, Kim B, Janssen-Megens EM, Schuringa JJ, Martens JHA. Tijchon E, et al. Among authors: janssen megens em. PLoS One. 2019 Dec 23;14(12):e0226435. doi: 10.1371/journal.pone.0226435. eCollection 2019. PLoS One. 2019. PMID: 31869378 Free PMC article.
29 results