Capuano B - Search Results

1

4-Phenylpyridin-2-one Derivatives: A Novel Class of Positive Allosteric Modulator of the M1 Muscarinic Acetylcholine Receptor.

Mistry SN, Jörg M, Lim H, Vinh NB, Sexton PM, Capuano B, Christopoulos A, Lane JR, Scammells PJ. Mistry SN, et al. Among authors: capuano b. J Med Chem. 2016 Jan 14;59(1):388-409. doi: 10.1021/acs.jmedchem.5b01562. Epub 2015 Dec 31. J Med Chem. 2016. PMID: 26624844

2

Schizophrenia: genesis, receptorology and current therapeutics.

Capuano B, Crosby IT, Lloyd EJ. Capuano B, et al. Curr Med Chem. 2002 Mar;9(5):521-48. doi: 10.2174/0929867024606939. Curr Med Chem. 2002. PMID: 11945123 Review.

3

Platensimycin: a promising antimicrobial targeting fatty acid synthesis.

Manallack DT, Crosby IT, Khakham Y, Capuano B. Manallack DT, et al. Among authors: capuano b. Curr Med Chem. 2008;15(7):705-10. doi: 10.2174/092986708783885255. Curr Med Chem. 2008. PMID: 18336284 Review.

4

Schizophrenia: a systematic review of the disease state, current therapeutics and their molecular mechanisms of action.

Shin JK, Malone DT, Crosby IT, Capuano B. Shin JK, et al. Among authors: capuano b. Curr Med Chem. 2011;18(9):1380-404. doi: 10.2174/092986711795029546. Curr Med Chem. 2011. PMID: 21366526 Review.

5

Design strategies for bivalent ligands targeting GPCRs.

Shonberg J, Scammells PJ, Capuano B. Shonberg J, et al. Among authors: capuano b. ChemMedChem. 2011 Jun 6;6(6):963-74. doi: 10.1002/cmdc.201100101. Epub 2011 Apr 21. ChemMedChem. 2011. PMID: 21520422 Review.

6

The design, synthesis and biological evaluation of novel URB602 analogues as potential monoacylglycerol lipase inhibitors.

Szabo M, Agostino M, Malone DT, Yuriev E, Capuano B. Szabo M, et al. Among authors: capuano b. Bioorg Med Chem Lett. 2011 Nov 15;21(22):6782-7. doi: 10.1016/j.bmcl.2011.09.038. Epub 2011 Sep 18. Bioorg Med Chem Lett. 2011. PMID: 21982493

7

Homobivalent ligands of the atypical antipsychotic clozapine: design, synthesis, and pharmacological evaluation.

McRobb FM, Crosby IT, Yuriev E, Lane JR, Capuano B. McRobb FM, et al. Among authors: capuano b. J Med Chem. 2012 Feb 23;55(4):1622-34. doi: 10.1021/jm201420s. Epub 2012 Feb 2. J Med Chem. 2012. PMID: 22243698

8

Synthesis and SAR study of 4-arylpiperidines and 4-aryl-1,2,3,6-tetrahydropyridines as 5-HT₂C agonists.

Conway RJ, Valant C, Christopoulos A, Robertson AD, Capuano B, Crosby IT. Conway RJ, et al. Among authors: capuano b. Bioorg Med Chem Lett. 2012 Apr 1;22(7):2560-4. doi: 10.1016/j.bmcl.2012.01.122. Epub 2012 Feb 9. Bioorg Med Chem Lett. 2012. PMID: 22381048

9

Synthesis and biological evaluation of N-substituted noscapine analogues.

DeBono AJ, Xie JH, Ventura S, Pouton CW, Capuano B, Scammells PJ. DeBono AJ, et al. Among authors: capuano b. ChemMedChem. 2012 Dec;7(12):2122-33. doi: 10.1002/cmdc.201200365. Epub 2012 Oct 10. ChemMedChem. 2012. PMID: 23055449

10

Novel adenosine A(2A) receptor ligands: a synthetic, functional and computational investigation of selected literature adenosine A(2A) receptor antagonists for extending into extracellular space.

Jörg M, Shonberg J, Mak FS, Miller ND, Yuriev E, Scammells PJ, Capuano B. Jörg M, et al. Among authors: capuano b. Bioorg Med Chem Lett. 2013 Jun 1;23(11):3427-33. doi: 10.1016/j.bmcl.2013.03.070. Epub 2013 Apr 2. Bioorg Med Chem Lett. 2013. PMID: 23602401

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