Kastan MB - Search Results

1

Optimization of a Novel Series of Ataxia-Telangiectasia Mutated Kinase Inhibitors as Potential Radiosensitizing Agents.

Min J, Guo K, Suryadevara PK, Zhu F, Holbrook G, Chen Y, Feau C, Young BM, Lemoff A, Connelly MC, Kastan MB, Guy RK. Min J, et al. Among authors: kastan mb. J Med Chem. 2016 Jan 28;59(2):559-77. doi: 10.1021/acs.jmedchem.5b01092. Epub 2016 Jan 12. J Med Chem. 2016. PMID: 26632965

2

Development of a cell-based, high-throughput screening assay for ATM kinase inhibitors.

Guo K, Shelat AA, Guy RK, Kastan MB. Guo K, et al. Among authors: kastan mb. J Biomol Screen. 2014 Apr;19(4):538-46. doi: 10.1177/1087057113520325. Epub 2014 Jan 24. J Biomol Screen. 2014. PMID: 24464432

3

Interactions of nucleolin and ribosomal protein L26 (RPL26) in translational control of human p53 mRNA.

Chen J, Guo K, Kastan MB. Chen J, et al. Among authors: kastan mb. J Biol Chem. 2012 May 11;287(20):16467-76. doi: 10.1074/jbc.M112.349274. Epub 2012 Mar 20. J Biol Chem. 2012. PMID: 22433872 Free PMC article.

4

Defective potassium currents in ataxia telangiectasia fibroblasts.

Rhodes N, D'Souza T, Foster CD, Ziv Y, Kirsch DG, Shiloh Y, Kastan MB, Reinhart PH, Gilmer TM. Rhodes N, et al. Among authors: kastan mb. Genes Dev. 1998 Dec 1;12(23):3686-92. doi: 10.1101/gad.12.23.3686. Genes Dev. 1998. PMID: 9851975 Free PMC article.

5

Chromatin perturbations during the DNA damage response in higher eukaryotes.

Bakkenist CJ, Kastan MB. Bakkenist CJ, et al. Among authors: kastan mb. DNA Repair (Amst). 2015 Dec;36:8-12. doi: 10.1016/j.dnarep.2015.09.002. Epub 2015 Sep 9. DNA Repair (Amst). 2015. PMID: 26391293 Free PMC article. Review.

6

Ataxia telangiectasia-mutated and p53 are potential mediators of chloroquine-induced resistance to mammary carcinogenesis.

Loehberg CR, Thompson T, Kastan MB, Maclean KH, Edwards DG, Kittrell FS, Medina D, Conneely OM, O'Malley BW. Loehberg CR, et al. Among authors: kastan mb. Cancer Res. 2007 Dec 15;67(24):12026-33. doi: 10.1158/0008-5472.CAN-07-3058. Cancer Res. 2007. PMID: 18089834

7

ATM functions at the peroxisome to induce pexophagy in response to ROS.

Zhang J, Tripathi DN, Jing J, Alexander A, Kim J, Powell RT, Dere R, Tait-Mulder J, Lee JH, Paull TT, Pandita RK, Charaka VK, Pandita TK, Kastan MB, Walker CL. Zhang J, et al. Among authors: kastan mb. Nat Cell Biol. 2015 Oct;17(10):1259-1269. doi: 10.1038/ncb3230. Epub 2015 Sep 7. Nat Cell Biol. 2015. PMID: 26344566 Free PMC article.

8

Retrospective Diagnosis of Ataxia-Telangiectasia in an Adolescent Patient With a Remote History of T-Cell Leukemia.

Sze SK, Lederman HM, Crawford TO, Wangler MF, Lewis AM, Kastan MB, Dibra HK, Taylor AMR, Wechsler DS. Sze SK, et al. Among authors: kastan mb. J Pediatr Hematol Oncol. 2021 Jan;43(1):e138-e140. doi: 10.1097/MPH.0000000000001672. J Pediatr Hematol Oncol. 2021. PMID: 31743320

9

Chromatin association of rad17 is required for an ataxia telangiectasia and rad-related kinase-mediated S-phase checkpoint in response to low-dose ultraviolet radiation.

Garg R, Callens S, Lim DS, Canman CE, Kastan MB, Xu B. Garg R, et al. Among authors: kastan mb. Mol Cancer Res. 2004 Jun;2(6):362-9. Mol Cancer Res. 2004. PMID: 15235112

10

Rad17 recruits the MRE11-RAD50-NBS1 complex to regulate the cellular response to DNA double-strand breaks.

Wang Q, Goldstein M, Alexander P, Wakeman TP, Sun T, Feng J, Lou Z, Kastan MB, Wang XF. Wang Q, et al. Among authors: kastan mb. EMBO J. 2014 Apr 16;33(8):862-77. doi: 10.1002/embj.201386064. Epub 2014 Feb 16. EMBO J. 2014. PMID: 24534091 Free PMC article.

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