Lemoff A - Search Results

1

Optimization of a Novel Series of Ataxia-Telangiectasia Mutated Kinase Inhibitors as Potential Radiosensitizing Agents.

Min J, Guo K, Suryadevara PK, Zhu F, Holbrook G, Chen Y, Feau C, Young BM, Lemoff A, Connelly MC, Kastan MB, Guy RK. Min J, et al. Among authors: lemoff a. J Med Chem. 2016 Jan 28;59(2):559-77. doi: 10.1021/acs.jmedchem.5b01092. Epub 2016 Jan 12. J Med Chem. 2016. PMID: 26632965

2

Optimization of propafenone analogues as antimalarial leads.

Lowes DJ, Guiguemde WA, Connelly MC, Zhu F, Sigal MS, Clark JA, Lemoff AS, Derisi JL, Wilson EB, Guy RK. Lowes DJ, et al. Among authors: lemoff as. J Med Chem. 2011 Nov 10;54(21):7477-85. doi: 10.1021/jm2005546. Epub 2011 Oct 10. J Med Chem. 2011. PMID: 21955244 Free PMC article.

3

Optimization of purine-nitrile TbcatB inhibitors for use in vivo and evaluation of efficacy in murine models.

Mallari JP, Zhu F, Lemoff A, Kaiser M, Lu M, Brun R, Guy RK. Mallari JP, et al. Among authors: lemoff a. Bioorg Med Chem. 2010 Dec 1;18(23):8302-9. doi: 10.1016/j.bmc.2010.09.073. Epub 2010 Oct 8. Bioorg Med Chem. 2010. PMID: 21051236

4

Synthesis and evaluation of sulfonylnitrophenylthiazoles (SNPTs) as thyroid hormone receptor-coactivator interaction inhibitors.

Hwang JY, Attia RR, Zhu F, Yang L, Lemoff A, Jeffries C, Connelly MC, Guy RK. Hwang JY, et al. Among authors: lemoff a. J Med Chem. 2012 Mar 8;55(5):2301-10. doi: 10.1021/jm201546m. Epub 2012 Feb 23. J Med Chem. 2012. PMID: 22324546 Free PMC article.

5

Lead optimization of antimalarial propafenone analogues.

Lowes D, Pradhan A, Iyer LV, Parman T, Gow J, Zhu F, Furimsky A, Lemoff A, Guiguemde WA, Sigal M, Clark JA, Wilson E, Tang L, Connelly MC, Derisi JL, Kyle DE, Mirsalis J, Guy RK. Lowes D, et al. Among authors: lemoff a. J Med Chem. 2012 Jul 12;55(13):6087-93. doi: 10.1021/jm300286a. Epub 2012 Jun 29. J Med Chem. 2012. PMID: 22708838 Free PMC article.

6

Evaluation of Diarylureas for Activity Against Plasmodium falciparum.

Zhang Y, Anderson M, Weisman JL, Lu M, Choy CJ, Boyd VA, Price J, Sigal M, Clark J, Connelly M, Zhu F, Guiguemde WA, Jeffries C, Yang L, Lemoff A, Liou AP, Webb TR, Derisi JL, Guy RK. Zhang Y, et al. Among authors: lemoff a. ACS Med Chem Lett. 2010 Dec 9;1(9):460-465. doi: 10.1021/ml100083c. ACS Med Chem Lett. 2010. PMID: 21243104 Free PMC article.

7

Modulation of esterified drug metabolism by tanshinones from Salvia miltiorrhiza ("Danshen").

Hatfield MJ, Tsurkan LG, Hyatt JL, Edwards CC, Lemoff A, Jeffries C, Yan B, Potter PM. Hatfield MJ, et al. Among authors: lemoff a. J Nat Prod. 2013 Jan 25;76(1):36-44. doi: 10.1021/np300628a. Epub 2013 Jan 3. J Nat Prod. 2013. PMID: 23286284 Free PMC article.

8

A dual regulatory circuit consisting of S-adenosylmethionine decarboxylase protein and its reaction product controls expression of the paralogous activator prozyme in Trypanosoma brucei.

Patel MM, Volkov OA, Leija C, Lemoff A, Phillips MA. Patel MM, et al. Among authors: lemoff a. PLoS Pathog. 2018 Oct 26;14(10):e1007404. doi: 10.1371/journal.ppat.1007404. eCollection 2018 Oct. PLoS Pathog. 2018. PMID: 30365568 Free PMC article.

9

Dual detection approach to a more accurate measure of relative purity in high-throughput characterization of compound collections.

Lemoff A, Yan B. Lemoff A, et al. J Comb Chem. 2008 Sep-Oct;10(5):746-51. doi: 10.1021/cc800100g. Epub 2008 Aug 13. J Comb Chem. 2008. PMID: 18698828

10

Structures of cationized proline analogues: evidence for the zwitterionic form.

Lemoff AS, Bush MF, Williams ER. Lemoff AS, et al. J Phys Chem A. 2005 Mar 10;109(9):1903-10. doi: 10.1021/jp0466800. J Phys Chem A. 2005. PMID: 16833523

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