Figg WD - Search Results

1

UGT1A1 genotype-dependent dose adjustment of belinostat in patients with advanced cancers using population pharmacokinetic modeling and simulation.

Peer CJ, Goey AK, Sissung TM, Erlich S, Lee MJ, Tomita Y, Trepel JB, Piekarz R, Balasubramaniam S, Bates SE, Figg WD. Peer CJ, et al. Among authors: figg wd. J Clin Pharmacol. 2016 Apr;56(4):450-60. doi: 10.1002/jcph.627. Epub 2015 Dec 4. J Clin Pharmacol. 2016. PMID: 26637161 Free PMC article. Clinical Trial.

2

Disposition of phenylbutyrate and its metabolites, phenylacetate and phenylacetylglutamine.

Piscitelli SC, Thibault A, Figg WD, Tompkins A, Headlee D, Lieberman R, Samid D, Myers CE. Piscitelli SC, et al. Among authors: figg wd. J Clin Pharmacol. 1995 Apr;35(4):368-73. doi: 10.1002/j.1552-4604.1995.tb04075.x. J Clin Pharmacol. 1995. PMID: 7650225 Clinical Trial.

3

Initial pharmacokinetics and bioavailability of PSC 833, a P-glycoprotein antagonist.

Lush RM, Meadows B, Fojo AT, Kalafsky G, Smith HT, Bates S, Figg WD. Lush RM, et al. Among authors: figg wd. J Clin Pharmacol. 1997 Feb;37(2):123-8. doi: 10.1002/j.1552-4604.1997.tb04770.x. J Clin Pharmacol. 1997. PMID: 9055138 Clinical Trial.

4

Phase I study of lovastatin, an inhibitor of the mevalonate pathway, in patients with cancer.

Thibault A, Samid D, Tompkins AC, Figg WD, Cooper MR, Hohl RJ, Trepel J, Liang B, Patronas N, Venzon DJ, Reed E, Myers CE. Thibault A, et al. Among authors: figg wd. Clin Cancer Res. 1996 Mar;2(3):483-91. Clin Cancer Res. 1996. PMID: 9816194 Clinical Trial.

5

Pharmacokinetics of cisplatin administered by continuous hyperthermic peritoneal perfusion (CHPP) to patients with peritoneal carcinomatosis.

Cho HK, Lush RM, Bartlett DL, Alexander HR, Wu PC, Libutti SK, Lee KB, Venzon DJ, Bauer KS, Reed E, Figg WD. Cho HK, et al. Among authors: figg wd. J Clin Pharmacol. 1999 Apr;39(4):394-401. doi: 10.1177/00912709922007967. J Clin Pharmacol. 1999. PMID: 10197298 Clinical Trial.

6

Phase I study of infusional paclitaxel in combination with the P-glycoprotein antagonist PSC 833.

Chico I, Kang MH, Bergan R, Abraham J, Bakke S, Meadows B, Rutt A, Robey R, Choyke P, Merino M, Goldspiel B, Smith T, Steinberg S, Figg WD, Fojo T, Bates S. Chico I, et al. Among authors: figg wd. J Clin Oncol. 2001 Feb 1;19(3):832-42. doi: 10.1200/JCO.2001.19.3.832. J Clin Oncol. 2001. PMID: 11157037 Clinical Trial.

7

The P-glycoprotein antagonist PSC 833 increases the plasma concentrations of 6alpha-hydroxypaclitaxel, a major metabolite of paclitaxel.

Kang MH, Figg WD, Ando Y, Blagosklonny MV, Liewehr D, Fojo T, Bates SE. Kang MH, et al. Among authors: figg wd. Clin Cancer Res. 2001 Jun;7(6):1610-7. Clin Cancer Res. 2001. PMID: 11410497 Clinical Trial.

8

The Hsp90 inhibitor geldanamycin selectively sensitizes Bcr-Abl-expressing leukemia cells to cytotoxic chemotherapy.

Blagosklonny MV, Fojo T, Bhalla KN, Kim JS, Trepel JB, Figg WD, Rivera Y, Neckers LM. Blagosklonny MV, et al. Among authors: figg wd. Leukemia. 2001 Oct;15(10):1537-43. doi: 10.1038/sj.leu.2402257. Leukemia. 2001. PMID: 11587211

9

A Phase I study of infusional vinblastine in combination with the P-glycoprotein antagonist PSC 833 (valspodar).

Bates S, Kang M, Meadows B, Bakke S, Choyke P, Merino M, Goldspiel B, Chico I, Smith T, Chen C, Robey R, Bergan R, Figg WD, Fojo T. Bates S, et al. Among authors: figg wd. Cancer. 2001 Sep 15;92(6):1577-90. doi: 10.1002/1097-0142(20010915)92:6<1577::aid-cncr1484>3.0.co;2-h. Cancer. 2001. PMID: 11745237 Clinical Trial.

10

Phase I trial of the histone deacetylase inhibitor, depsipeptide (FR901228, NSC 630176), in patients with refractory neoplasms.

Sandor V, Bakke S, Robey RW, Kang MH, Blagosklonny MV, Bender J, Brooks R, Piekarz RL, Tucker E, Figg WD, Chan KK, Goldspiel B, Fojo AT, Balcerzak SP, Bates SE. Sandor V, et al. Among authors: figg wd. Clin Cancer Res. 2002 Mar;8(3):718-28. Clin Cancer Res. 2002. PMID: 11895901 Clinical Trial.

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