Skerra A - Search Results

1

Functional characterization of a VEGF-A-targeting Anticalin, prototype of a novel therapeutic human protein class.

Gille H, Hülsmeyer M, Trentmann S, Matschiner G, Christian HJ, Meyer T, Amirkhosravi A, Audoly LP, Hohlbaum AM, Skerra A. Gille H, et al. Among authors: skerra a. Angiogenesis. 2016 Jan;19(1):79-94. doi: 10.1007/s10456-015-9490-5. Epub 2015 Dec 9. Angiogenesis. 2016. PMID: 26650228

2

Anticalins as alternative binding proteins for therapeutic use.

Skerra A. Skerra A. Curr Opin Mol Ther. 2007 Aug;9(4):336-44. Curr Opin Mol Ther. 2007. PMID: 17694446 Review.

3

An engineered lipocalin specific for CTLA-4 reveals a combining site with structural and conformational features similar to antibodies.

Schönfeld D, Matschiner G, Chatwell L, Trentmann S, Gille H, Hülsmeyer M, Brown N, Kaye PM, Schlehuber S, Hohlbaum AM, Skerra A. Schönfeld D, et al. Among authors: skerra a. Proc Natl Acad Sci U S A. 2009 May 19;106(20):8198-203. doi: 10.1073/pnas.0813399106. Epub 2009 May 5. Proc Natl Acad Sci U S A. 2009. PMID: 19416843 Free PMC article.

4

Anticalins: the lipocalin family as a novel protein scaffold for the development of next-generation immunotherapies.

Hohlbaum AM, Skerra A. Hohlbaum AM, et al. Among authors: skerra a. Expert Rev Clin Immunol. 2007 Jul;3(4):491-501. doi: 10.1586/1744666X.3.4.491. Expert Rev Clin Immunol. 2007. PMID: 20477155

5

High-throughput sorting of an Anticalin library via EspP-mediated functional display on the Escherichia coli cell surface.

Binder U, Matschiner G, Theobald I, Skerra A. Binder U, et al. Among authors: skerra a. J Mol Biol. 2010 Jul 23;400(4):783-802. doi: 10.1016/j.jmb.2010.05.049. Epub 2010 May 26. J Mol Biol. 2010. PMID: 20630471

6

Combinatorial design of an Anticalin directed against the extra-domain b for the specific targeting of oncofetal fibronectin.

Gebauer M, Schiefner A, Matschiner G, Skerra A. Gebauer M, et al. Among authors: skerra a. J Mol Biol. 2013 Feb 22;425(4):780-802. doi: 10.1016/j.jmb.2012.12.004. Epub 2012 Dec 10. J Mol Biol. 2013. PMID: 23238252

7

Selection and characterization of Anticalins targeting human prostate-specific membrane antigen (PSMA).

Barinka C, Ptacek J, Richter A, Novakova Z, Morath V, Skerra A. Barinka C, et al. Among authors: skerra a. Protein Eng Des Sel. 2016 Mar;29(3):105-15. doi: 10.1093/protein/gzv065. Epub 2016 Jan 21. Protein Eng Des Sel. 2016. PMID: 26802163

8

Anticalin^® Proteins as Therapeutic Agents in Human Diseases.

Rothe C, Skerra A. Rothe C, et al. Among authors: skerra a. BioDrugs. 2018 Jun;32(3):233-243. doi: 10.1007/s40259-018-0278-1. BioDrugs. 2018. PMID: 29748739 Free PMC article. Review.

9

Development of a high affinity Anticalin^® directed against human CD98hc for theranostic applications.

Deuschle FC, Morath V, Schiefner A, Brandt C, Ballke S, Reder S, Steiger K, Schwaiger M, Weber W, Skerra A. Deuschle FC, et al. Among authors: skerra a. Theranostics. 2020 Jan 12;10(5):2172-2187. doi: 10.7150/thno.38968. eCollection 2020. Theranostics. 2020. PMID: 32089738 Free PMC article.

10

Design of a surrogate Anticalin protein directed against CD98hc for preclinical studies in mice.

Deuschle FC, Schiefner A, Brandt C, Skerra A. Deuschle FC, et al. Among authors: skerra a. Protein Sci. 2020 Aug;29(8):1774-1783. doi: 10.1002/pro.3894. Epub 2020 Jun 16. Protein Sci. 2020. PMID: 32463547 Free PMC article.

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