Clemons PA - Search Results

1

Identification of cancer-cytotoxic modulators of PDE3A by predictive chemogenomics.

de Waal L, Lewis TA, Rees MG, Tsherniak A, Wu X, Choi PS, Gechijian L, Hartigan C, Faloon PW, Hickey MJ, Tolliday N, Carr SA, Clemons PA, Munoz B, Wagner BK, Shamji AF, Koehler AN, Schenone M, Burgin AB, Schreiber SL, Greulich H, Meyerson M. de Waal L, et al. Among authors: clemons pa. Nat Chem Biol. 2016 Feb;12(2):102-8. doi: 10.1038/nchembio.1984. Epub 2015 Dec 14. Nat Chem Biol. 2016. PMID: 26656089 Free PMC article.

2

Exploiting site-site interactions on solid support to generate dimeric molecules.

Blackwell HE, Clemons PA, Schreiber SL. Blackwell HE, et al. Among authors: clemons pa. Org Lett. 2001 Apr 19;3(8):1185-8. doi: 10.1021/ol015647i. Org Lett. 2001. PMID: 11348190

3

A one-bead, one-stock solution approach to chemical genetics: part 2.

Clemons PA, Koehler AN, Wagner BK, Sprigings TG, Spring DR, King RW, Schreiber SL, Foley MA. Clemons PA, et al. Chem Biol. 2001 Dec;8(12):1183-95. doi: 10.1016/s1074-5521(01)00086-2. Chem Biol. 2001. PMID: 11755397

4

Synthesis of calcineurin-resistant derivatives of FK506 and selection of compensatory receptors.

Clemons PA, Gladstone BG, Seth A, Chao ED, Foley MA, Schreiber SL. Clemons PA, et al. Chem Biol. 2002 Jan;9(1):49-61. doi: 10.1016/s1074-5521(02)00085-6. Chem Biol. 2002. PMID: 11841938

5

Chemical genomic profiling of biological networks using graph theory and combinations of small molecule perturbations.

Haggarty SJ, Clemons PA, Schreiber SL. Haggarty SJ, et al. Among authors: clemons pa. J Am Chem Soc. 2003 Sep 3;125(35):10543-5. doi: 10.1021/ja035413p. J Am Chem Soc. 2003. PMID: 12940736

6

Chemical genomics: probing protein function using small molecules.

Wagner BK, Haggarty SJ, Clemons PA. Wagner BK, et al. Among authors: clemons pa. Am J Pharmacogenomics. 2004;4(5):313-20. doi: 10.2165/00129785-200404050-00004. Am J Pharmacogenomics. 2004. PMID: 15462609 Review.

7

Relationship of stereochemical and skeletal diversity of small molecules to cellular measurement space.

Kim YK, Arai MA, Arai T, Lamenzo JO, Dean EF 3rd, Patterson N, Clemons PA, Schreiber SL. Kim YK, et al. Among authors: clemons pa. J Am Chem Soc. 2004 Nov 17;126(45):14740-5. doi: 10.1021/ja048170p. J Am Chem Soc. 2004. PMID: 15535697

8

Mapping chemical space using molecular descriptors and chemical genetics: deacetylase inhibitors.

Haggarty SJ, Clemons PA, Wong JC, Schreiber SL. Haggarty SJ, et al. Among authors: clemons pa. Comb Chem High Throughput Screen. 2004 Nov;7(7):669-76. doi: 10.2174/1386207043328319. Comb Chem High Throughput Screen. 2004. PMID: 15578929 Review.

9

SpectralNET--an application for spectral graph analysis and visualization.

Forman JJ, Clemons PA, Schreiber SL, Haggarty SJ. Forman JJ, et al. Among authors: clemons pa. BMC Bioinformatics. 2005 Oct 19;6:260. doi: 10.1186/1471-2105-6-260. BMC Bioinformatics. 2005. PMID: 16236170 Free PMC article.

10

Small molecules, big players: the National Cancer Institute's Initiative for Chemical Genetics.

Tolliday N, Clemons PA, Ferraiolo P, Koehler AN, Lewis TA, Li X, Schreiber SL, Gerhard DS, Eliasof S. Tolliday N, et al. Among authors: clemons pa. Cancer Res. 2006 Sep 15;66(18):8935-42. doi: 10.1158/0008-5472.CAN-06-2552. Cancer Res. 2006. PMID: 16982730 Free article.

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