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DNA methylation changes in plasticity genes accompany the formation and maintenance of memory.
Halder R, Hennion M, Vidal RO, Shomroni O, Rahman RU, Rajput A, Centeno TP, van Bebber F, Capece V, Garcia Vizcaino JC, Schuetz AL, Burkhardt S, Benito E, Navarro Sala M, Javan SB, Haass C, Schmid B, Fischer A, Bonn S. Halder R, et al. Among authors: burkhardt s. Nat Neurosci. 2016 Jan;19(1):102-10. doi: 10.1038/nn.4194. Epub 2015 Dec 14. Nat Neurosci. 2016. PMID: 26656643
Histone-methyltransferase MLL2 (KMT2B) is required for memory formation in mice.
Kerimoglu C, Agis-Balboa RC, Kranz A, Stilling R, Bahari-Javan S, Benito-Garagorri E, Halder R, Burkhardt S, Stewart AF, Fischer A. Kerimoglu C, et al. Among authors: burkhardt s. J Neurosci. 2013 Feb 20;33(8):3452-64. doi: 10.1523/JNEUROSCI.3356-12.2013. J Neurosci. 2013. PMID: 23426673 Free PMC article.
The BET/BRD inhibitor JQ1 improves brain plasticity in WT and APP mice.
Benito E, Ramachandran B, Schroeder H, Schmidt G, Urbanke H, Burkhardt S, Capece V, Dean C, Fischer A. Benito E, et al. Among authors: burkhardt s. Transl Psychiatry. 2017 Sep 26;7(9):e1239. doi: 10.1038/tp.2017.202. Transl Psychiatry. 2017. PMID: 28949335 Free PMC article.
K-Lysine acetyltransferase 2a regulates a hippocampal gene expression network linked to memory formation.
Stilling RM, Rönicke R, Benito E, Urbanke H, Capece V, Burkhardt S, Bahari-Javan S, Barth J, Sananbenesi F, Schütz AL, Dyczkowski J, Martinez-Hernandez A, Kerimoglu C, Dent SY, Bonn S, Reymann KG, Fischer A. Stilling RM, et al. Among authors: burkhardt s. EMBO J. 2014 Sep 1;33(17):1912-27. doi: 10.15252/embj.201487870. Epub 2014 Jul 14. EMBO J. 2014. PMID: 25024434 Free PMC article.
KMT2A and KMT2B Mediate Memory Function by Affecting Distinct Genomic Regions.
Kerimoglu C, Sakib MS, Jain G, Benito E, Burkhardt S, Capece V, Kaurani L, Halder R, Agís-Balboa RC, Stilling R, Urbanke H, Kranz A, Stewart AF, Fischer A. Kerimoglu C, et al. Among authors: burkhardt s. Cell Rep. 2017 Jul 18;20(3):538-548. doi: 10.1016/j.celrep.2017.06.072. Cell Rep. 2017. PMID: 28723559 Free article.
HDAC inhibitor-dependent transcriptome and memory reinstatement in cognitive decline models.
Benito E, Urbanke H, Ramachandran B, Barth J, Halder R, Awasthi A, Jain G, Capece V, Burkhardt S, Navarro-Sala M, Nagarajan S, Schütz AL, Johnsen SA, Bonn S, Lührmann R, Dean C, Fischer A. Benito E, et al. Among authors: burkhardt s. J Clin Invest. 2015 Sep;125(9):3572-84. doi: 10.1172/JCI79942. Epub 2015 Aug 17. J Clin Invest. 2015. PMID: 26280576 Free PMC article.
Changes in m6A RNA methylation contribute to heart failure progression by modulating translation.
Berulava T, Buchholz E, Elerdashvili V, Pena T, Islam MR, Lbik D, Mohamed BA, Renner A, von Lewinski D, Sacherer M, Bohnsack KE, Bohnsack MT, Jain G, Capece V, Cleve N, Burkhardt S, Hasenfuss G, Fischer A, Toischer K. Berulava T, et al. Among authors: burkhardt s. Eur J Heart Fail. 2020 Jan;22(1):54-66. doi: 10.1002/ejhf.1672. Epub 2019 Dec 17. Eur J Heart Fail. 2020. PMID: 31849158 Free article.
HDAC1 regulates fear extinction in mice.
Bahari-Javan S, Maddalena A, Kerimoglu C, Wittnam J, Held T, Bähr M, Burkhardt S, Delalle I, Kügler S, Fischer A, Sananbenesi F. Bahari-Javan S, et al. Among authors: burkhardt s. J Neurosci. 2012 Apr 11;32(15):5062-73. doi: 10.1523/JNEUROSCI.0079-12.2012. J Neurosci. 2012. PMID: 22496552 Free PMC article.
152 results