Baskin R - Search Results

1

Enhancer scanning to locate regulatory regions in genomic loci.

Buckley M, Gjyshi A, Mendoza-Fandiño G, Baskin R, Carvalho RS, Carvalho MA, Woods NT, Monteiro AN. Buckley M, et al. Among authors: baskin r. Nat Protoc. 2016 Jan;11(1):46-60. doi: 10.1038/nprot.2015.136. Epub 2015 Dec 10. Nat Protoc. 2016. PMID: 26658467 Free PMC article.

2

Functional analysis of the 11q23.3 glioma susceptibility locus implicates PHLDB1 and DDX6 in glioma susceptibility.

Baskin R, Woods NT, Mendoza-Fandiño G, Forsyth P, Egan KM, Monteiro AN. Baskin R, et al. Sci Rep. 2015 Nov 27;5:17367. doi: 10.1038/srep17367. Sci Rep. 2015. PMID: 26610392 Free PMC article.

3

Brain tumor risk according to germ-line variation in the MLLT10 locus.

Egan KM, Baskin R, Nabors LB, Thompson RC, Olson JJ, Browning JE, Madden MH, Monteiro AN. Egan KM, et al. Among authors: baskin r. Eur J Hum Genet. 2015 Jan;23(1):132-4. doi: 10.1038/ejhg.2014.70. Epub 2014 Apr 23. Eur J Hum Genet. 2015. PMID: 24755950 Free PMC article.

4

Functional assays provide a robust tool for the clinical annotation of genetic variants of uncertain significance.

Woods NT, Baskin R, Golubeva V, Jhuraney A, De-Gregoriis G, Vaclova T, Goldgar DE, Couch FJ, Carvalho MA, Iversen ES, Monteiro AN. Woods NT, et al. Among authors: baskin r. NPJ Genom Med. 2016;1:16001-. doi: 10.1038/npjgenmed.2016.1. Epub 2016 Mar 2. NPJ Genom Med. 2016. PMID: 28781887 Free PMC article.

5

The Jak2 small molecule inhibitor, G6, reduces the tumorigenic potential of T98G glioblastoma cells in vitro and in vivo.

Baskin R, Park SO, Keserű GM, Bisht KS, Wamsley HL, Sayeski PP. Baskin R, et al. PLoS One. 2014 Aug 27;9(8):e105568. doi: 10.1371/journal.pone.0105568. eCollection 2014. PLoS One. 2014. PMID: 25162558 Free PMC article.

6

The recent medicinal chemistry development of Jak2 tyrosine kinase small molecule inhibitors.

Baskin R, Majumder A, Sayeski PP. Baskin R, et al. Curr Med Chem. 2010;17(36):4551-8. doi: 10.2174/092986710794182953. Curr Med Chem. 2010. PMID: 21062251 Free PMC article. Review.

7

Structure-function correlation of G6, a novel small molecule inhibitor of Jak2: indispensability of the stilbenoid core.

Majumder A, Govindasamy L, Magis A, Kiss R, Polgár T, Baskin R, Allan RW, Agbandje-McKenna M, Reuther GW, Keseru GM, Bisht KS, Sayeski PP. Majumder A, et al. Among authors: baskin r. J Biol Chem. 2010 Oct 8;285(41):31399-407. doi: 10.1074/jbc.M110.168211. Epub 2010 Jul 28. J Biol Chem. 2010. PMID: 20667821 Free PMC article.

8

Angiotensin II mediates cell survival through upregulation and activation of the serum and glucocorticoid inducible kinase 1.

Baskin R, Sayeski PP. Baskin R, et al. Cell Signal. 2012 Feb;24(2):435-442. doi: 10.1016/j.cellsig.2011.09.016. Epub 2011 Sep 22. Cell Signal. 2012. PMID: 21963429 Free PMC article.

9

A46, a benzothiophene-derived compound, suppresses Jak2-mediated pathologic cell growth.

Majumder A, Magis AT, Park SO, Figueroa NC, Baskin R, Kirabo A, Allan RW, Zhao ZJ, Bisht KS, Keseru GM, Sayeski PP. Majumder A, et al. Among authors: baskin r. Exp Hematol. 2012 Jan;40(1):22-34. doi: 10.1016/j.exphem.2011.10.003. Epub 2011 Oct 20. Exp Hematol. 2012. PMID: 22019628 Free PMC article.

10

Identification of novel SAR properties of the Jak2 small molecule inhibitor G6: significance of the para-hydroxyl orientation.

Baskin R, Gali M, Park SO, Zhao ZJ, Keseru GM, Bisht KS, Sayeski PP. Baskin R, et al. Bioorg Med Chem Lett. 2012 Feb 1;22(3):1402-7. doi: 10.1016/j.bmcl.2011.12.042. Epub 2011 Dec 21. Bioorg Med Chem Lett. 2012. PMID: 22227213 Free PMC article.

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