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Endothelial cell-derived angiopoietin-2 is a therapeutic target in treatment-naive and bevacizumab-resistant glioblastoma.
Scholz A, Harter PN, Cremer S, Yalcin BH, Gurnik S, Yamaji M, Di Tacchio M, Sommer K, Baumgarten P, Bähr O, Steinbach JP, Trojan J, Glas M, Herrlinger U, Krex D, Meinhardt M, Weyerbrock A, Timmer M, Goldbrunner R, Deckert M, Braun C, Schittenhelm J, Frueh JT, Ullrich E, Mittelbronn M, Plate KH, Reiss Y. Scholz A, et al. Among authors: mittelbronn m. EMBO Mol Med. 2016 Jan 1;8(1):39-57. doi: 10.15252/emmm.201505505. EMBO Mol Med. 2016. PMID: 26666269 Free PMC article.
The astrocytic response towards invasive meningiomas.
Zeltner L, Schittenhelm J, Mittelbronn M, Roser F, Tatagiba M, Mawrin C, Kim YJ, Bornemann A. Zeltner L, et al. Among authors: mittelbronn m. Neuropathol Appl Neurobiol. 2007 Apr;33(2):163-8. doi: 10.1111/j.1365-2990.2006.00792.x. Neuropathol Appl Neurobiol. 2007. PMID: 17359357
EGR-1 is regulated by N-methyl-D-aspartate-receptor stimulation and associated with patient survival in human high grade astrocytomas.
Mittelbronn M, Harter P, Warth A, Lupescu A, Schilbach K, Vollmann H, Capper D, Goeppert B, Frei K, Bertalanffy H, Weller M, Meyermann R, Lang F, Simon P. Mittelbronn M, et al. Brain Pathol. 2009 Apr;19(2):195-204. doi: 10.1111/j.1750-3639.2008.00175.x. Epub 2008 May 16. Brain Pathol. 2009. PMID: 18489490 Free PMC article.
Secreted protein, acidic and rich in cysteine (SPARC) expression in astrocytic tumour cells negatively correlates with proliferation, while vascular SPARC expression is associated with patient survival.
Capper D, Mittelbronn M, Goeppert B, Meyermann R, Schittenhelm J. Capper D, et al. Among authors: mittelbronn m. Neuropathol Appl Neurobiol. 2010 Apr;36(3):183-97. doi: 10.1111/j.1365-2990.2010.01072.x. Epub 2010 Feb 4. Neuropathol Appl Neurobiol. 2010. PMID: 20132490
348 results