Manoharan M - Search Results

1

5'-C-Malonyl RNA: Small Interfering RNAs Modified with 5'-Monophosphate Bioisostere Demonstrate Gene Silencing Activity.

Zlatev I, Foster DJ, Liu J, Charisse K, Brigham B, Parmar RG, Jadhav V, Maier MA, Rajeev KG, Egli M, Manoharan M. Zlatev I, et al. Among authors: manoharan m. ACS Chem Biol. 2016 Apr 15;11(4):953-60. doi: 10.1021/acschembio.5b00654. Epub 2016 Jan 13. ACS Chem Biol. 2016. PMID: 26675211

2

Synthesis of chimeric oligonucleotides containing phosphodiester, phosphorothioate, and phosphoramidate linkages.

Maier MA, Guzaev AP, Manoharan M. Maier MA, et al. Among authors: manoharan m. Org Lett. 2000 Jun 29;2(13):1819-22. doi: 10.1021/ol005842h. Org Lett. 2000. PMID: 10891166

3

Detection of alkali metal ions in DNA crystals using state-of-the-art X-ray diffraction experiments.

Tereshko V, Wilds CJ, Minasov G, Prakash TP, Maier MA, Howard A, Wawrzak Z, Manoharan M, Egli M. Tereshko V, et al. Among authors: manoharan m. Nucleic Acids Res. 2001 Mar 1;29(5):1208-15. doi: 10.1093/nar/29.5.1208. Nucleic Acids Res. 2001. PMID: 11222771 Free PMC article.

4

Synthesis of novel 3'-C-methylene thymidine and 5-methyluridine/cytidine H-phosphonates and phosphonamidites for new backbone modification of oligonucleotides.

An H, Wang T, Maier MA, Manoharan M, Ross BS, Cook PD. An H, et al. Among authors: manoharan m. J Org Chem. 2001 Apr 20;66(8):2789-801. doi: 10.1021/jo001699u. J Org Chem. 2001. PMID: 11304203

5

Peptide nucleic acids are potent modulators of endogenous pre-mRNA splicing of the murine interleukin-5 receptor-alpha chain.

Karras JG, Maier MA, Lu T, Watt A, Manoharan M. Karras JG, et al. Among authors: manoharan m. Biochemistry. 2001 Jul 3;40(26):7853-9. doi: 10.1021/bi010263l. Biochemistry. 2001. PMID: 11425312

6

Nuclease resistance of oligonucleotides containing the tricyclic cytosine analogues phenoxazine and 9-(2-aminoethoxy)-phenoxazine ("G-clamp") and origins of their nuclease resistance properties.

Maier MA, Leeds JM, Balow G, Springer RH, Bharadwaj R, Manoharan M. Maier MA, et al. Among authors: manoharan m. Biochemistry. 2002 Jan 29;41(4):1323-7. doi: 10.1021/bi011725y. Biochemistry. 2002. PMID: 11802733

7

2'-O-[2-(methylthio)ethyl]-modified oligonucleotide: an analogue of 2'-O-[2-(methoxy)-ethyl]-modified oligonucleotide with improved protein binding properties and high binding affinity to target RNA.

Prakash TP, Manoharan M, Kawasaki AM, Fraser AS, Lesnik EA, Sioufi N, Leeds JM, Teplova M, Egli M. Prakash TP, et al. Among authors: manoharan m. Biochemistry. 2002 Oct 1;41(39):11642-8. doi: 10.1021/bi020264t. Biochemistry. 2002. PMID: 12269806

8

Systemically delivered antisense oligomers upregulate gene expression in mouse tissues.

Sazani P, Gemignani F, Kang SH, Maier MA, Manoharan M, Persmark M, Bortner D, Kole R. Sazani P, et al. Among authors: manoharan m. Nat Biotechnol. 2002 Dec;20(12):1228-33. doi: 10.1038/nbt759. Epub 2002 Nov 11. Nat Biotechnol. 2002. PMID: 12426578

9

High-affinity peptide nucleic acid oligomers containing tricyclic cytosine analogues.

Rajeev KG, Maier MA, Lesnik EA, Manoharan M. Rajeev KG, et al. Among authors: manoharan m. Org Lett. 2002 Dec 12;4(25):4395-8. doi: 10.1021/ol027026a. Org Lett. 2002. PMID: 12465896

10

Direct observation of a cytosine analogue that forms five hydrogen bonds to guanosine: guanidino G-clamp.

Wilds CJ, Maier MA, Tereshko V, Manoharan M, Egli M. Wilds CJ, et al. Among authors: manoharan m. Angew Chem Int Ed Engl. 2002 Jan 4;41(1):115-7. doi: 10.1002/1521-3773(20020104)41:1<115::aid-anie115>3.0.co;2-r. Angew Chem Int Ed Engl. 2002. PMID: 12491456 No abstract available.

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