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Decreased epigenetic age of PBMCs from Italian semi-supercentenarians and their offspring.
Horvath S, Pirazzini C, Bacalini MG, Gentilini D, Di Blasio AM, Delledonne M, Mari D, Arosio B, Monti D, Passarino G, De Rango F, D'Aquila P, Giuliani C, Marasco E, Collino S, Descombes P, Garagnani P, Franceschi C. Horvath S, et al. Among authors: descombes p. Aging (Albany NY). 2015 Dec;7(12):1159-70. doi: 10.18632/aging.100861. Aging (Albany NY). 2015. PMID: 26678252 Free PMC article.
Whole-genome sequencing analysis of semi-supercentenarians.
Garagnani P, Marquis J, Delledonne M, Pirazzini C, Marasco E, Kwiatkowska KM, Iannuzzi V, Bacalini MG, Valsesia A, Carayol J, Raymond F, Ferrarini A, Xumerle L, Collino S, Mari D, Arosio B, Casati M, Ferri E, Monti D, Nacmias B, Sorbi S, Luiselli D, Pettener D, Castellani G, Sala C, Passarino G, De Rango F, D'Aquila P, Bertamini L, Martinelli N, Girelli D, Olivieri O, Giuliani C, Descombes P, Franceschi C. Garagnani P, et al. Among authors: descombes p. Elife. 2021 May 4;10:e57849. doi: 10.7554/eLife.57849. Elife. 2021. PMID: 33941312 Free PMC article.
Genomic history of the Italian population recapitulates key evolutionary dynamics of both Continental and Southern Europeans.
Sazzini M, Abondio P, Sarno S, Gnecchi-Ruscone GA, Ragno M, Giuliani C, De Fanti S, Ojeda-Granados C, Boattini A, Marquis J, Valsesia A, Carayol J, Raymond F, Pirazzini C, Marasco E, Ferrarini A, Xumerle L, Collino S, Mari D, Arosio B, Monti D, Passarino G, D'Aquila P, Pettener D, Luiselli D, Castellani G, Delledonne M, Descombes P, Franceschi C, Garagnani P. Sazzini M, et al. Among authors: descombes p. BMC Biol. 2020 May 22;18(1):51. doi: 10.1186/s12915-020-00778-4. BMC Biol. 2020. PMID: 32438927 Free PMC article.
The three genetics (nuclear DNA, mitochondrial DNA, and gut microbiome) of longevity in humans considered as metaorganisms.
Garagnani P, Pirazzini C, Giuliani C, Candela M, Brigidi P, Sevini F, Luiselli D, Bacalini MG, Salvioli S, Capri M, Monti D, Mari D, Collino S, Delledonne M, Descombes P, Franceschi C. Garagnani P, et al. Among authors: descombes p. Biomed Res Int. 2014;2014:560340. doi: 10.1155/2014/560340. Epub 2014 Apr 24. Biomed Res Int. 2014. PMID: 24868529 Free PMC article. Review.
Centenarians as extreme phenotypes: An ecological perspective to get insight into the relationship between the genetics of longevity and age-associated diseases.
Giuliani C, Pirazzini C, Delledonne M, Xumerle L, Descombes P, Marquis J, Mengozzi G, Monti D, Bellizzi D, Passarino G, Luiselli D, Franceschi C, Garagnani P. Giuliani C, et al. Among authors: descombes p. Mech Ageing Dev. 2017 Jul;165(Pt B):195-201. doi: 10.1016/j.mad.2017.02.007. Epub 2017 Feb 27. Mech Ageing Dev. 2017. PMID: 28242236 Review.
The Use of Non-Variant Sites to Improve the Clinical Assessment of Whole-Genome Sequence Data.
Ferrarini A, Xumerle L, Griggio F, Garonzi M, Cantaloni C, Centomo C, Vargas SM, Descombes P, Marquis J, Collino S, Franceschi C, Garagnani P, Salisbury BA, Harvey JM, Delledonne M. Ferrarini A, et al. Among authors: descombes p. PLoS One. 2015 Jul 6;10(7):e0132180. doi: 10.1371/journal.pone.0132180. eCollection 2015. PLoS One. 2015. PMID: 26147798 Free PMC article.
A robust neuromuscular system protects rat and human skeletal muscle from sarcopenia.
Pannérec A, Springer M, Migliavacca E, Ireland A, Piasecki M, Karaz S, Jacot G, Métairon S, Danenberg E, Raymond F, Descombes P, McPhee JS, Feige JN. Pannérec A, et al. Among authors: descombes p. Aging (Albany NY). 2016 Apr;8(4):712-29. doi: 10.18632/aging.100926. Aging (Albany NY). 2016. PMID: 27019136 Free PMC article.
One-carbon metabolism, cognitive impairment and CSF measures of Alzheimer pathology: homocysteine and beyond.
Dayon L, Guiraud SP, Corthésy J, Da Silva L, Migliavacca E, Tautvydaitė D, Oikonomidi A, Moullet B, Henry H, Métairon S, Marquis J, Descombes P, Collino S, Martin FJ, Montoliu I, Kussmann M, Wojcik J, Bowman GL, Popp J. Dayon L, et al. Among authors: descombes p. Alzheimers Res Ther. 2017 Jun 17;9(1):43. doi: 10.1186/s13195-017-0270-x. Alzheimers Res Ther. 2017. PMID: 28623948 Free PMC article.
Genome-wide mRNA expression correlates of viral control in CD4+ T-cells from HIV-1-infected individuals.
Rotger M, Dang KK, Fellay J, Heinzen EL, Feng S, Descombes P, Shianna KV, Ge D, Günthard HF, Goldstein DB, Telenti A; Swiss HIV Cohort Study; Center for HIV/AIDS Vaccine Immunology. Rotger M, et al. Among authors: descombes p. PLoS Pathog. 2010 Feb 26;6(2):e1000781. doi: 10.1371/journal.ppat.1000781. PLoS Pathog. 2010. PMID: 20195503 Free PMC article.
173 results