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Inhibition of protein N-myristoylation blocks Plasmodium falciparum intraerythrocytic development, egress and invasion.
Schlott AC, Knuepfer E, Green JL, Hobson P, Borg AJ, Morales-Sanfrutos J, Perrin AJ, Maclachlan C, Collinson LM, Snijders AP, Tate EW, Holder AA. Schlott AC, et al. Among authors: perrin aj. PLoS Biol. 2021 Oct 25;19(10):e3001408. doi: 10.1371/journal.pbio.3001408. eCollection 2021 Oct. PLoS Biol. 2021. PMID: 34695132 Free PMC article.
Ca2+ signals critical for egress and gametogenesis in malaria parasites depend on a multipass membrane protein that interacts with PKG.
Balestra AC, Koussis K, Klages N, Howell SA, Flynn HR, Bantscheff M, Pasquarello C, Perrin AJ, Brusini L, Arboit P, Sanz O, Castaño LP, Withers-Martinez C, Hainard A, Ghidelli-Disse S, Snijders AP, Baker DA, Blackman MJ, Brochet M. Balestra AC, et al. Among authors: perrin aj. Sci Adv. 2021 Mar 24;7(13):eabe5396. doi: 10.1126/sciadv.abe5396. Print 2021 Mar. Sci Adv. 2021. PMID: 33762339 Free PMC article.
41 results