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A highly sensitive and selective LC-MS/MS method to quantify asunaprevir, an HCV NS3 protease inhibitor, in human plasma in support of pharmacokinetic studies.
Kandoussi H, Jiang H, Zeng J, Zheng N, Kadiyala P, Eley T, He B, Garimella T, Demers R, Cojocaru L, Aubry AF, Arnold ME. Kandoussi H, et al. Among authors: aubry af. J Pharm Biomed Anal. 2016 Feb 5;119:145-51. doi: 10.1016/j.jpba.2015.11.028. Epub 2015 Nov 23. J Pharm Biomed Anal. 2016. PMID: 26683987
Sensitive and accurate liquid chromatography-tandem mass spectrometry methods for quantitative determination of a novel hepatitis C NS5B inhibitor BMS-791325 and its active metabolite in human plasma and urine.
Jiang H, Demers R, Kandoussi H, Burrell R, Eley T, Kadiyala P, Cojocaru L, Baker C, Ryan J, Aubry AF, Arnold ME, Zeng J. Jiang H, et al. Among authors: aubry af. J Pharm Biomed Anal. 2015 Mar 25;107:17-23. doi: 10.1016/j.jpba.2014.12.011. Epub 2014 Dec 17. J Pharm Biomed Anal. 2015. PMID: 25562845
Multiplexed LC-MS/MS method for the simultaneous quantitation of three novel hepatitis C antivirals, daclatasvir, asunaprevir, and beclabuvir in human plasma.
Jiang H, Kandoussi H, Zeng J, Wang J, Demers R, Eley T, He B, Burrell R, Easter J, Kadiyala P, Pursley J, Cojocaru L, Baker C, Ryan J, Aubry AF, Arnold ME. Jiang H, et al. Among authors: aubry af. J Pharm Biomed Anal. 2015 Mar 25;107:409-18. doi: 10.1016/j.jpba.2015.01.027. Epub 2015 Jan 20. J Pharm Biomed Anal. 2015. PMID: 25676854
Post-pellet-digestion precipitation and solid phase extraction: A practical and efficient workflow to extract surrogate peptides for ultra-high performance liquid chromatography--tandem mass spectrometry bioanalysis of a therapeutic antibody in the low ng/mL range.
Gong C, Zheng N, Zeng J, Aubry AF, Arnold ME. Gong C, et al. Among authors: aubry af. J Chromatogr A. 2015 Dec 11;1424:27-36. doi: 10.1016/j.chroma.2015.10.049. Epub 2015 Oct 19. J Chromatogr A. 2015. PMID: 26525666
75 results