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Page 1
CDK12 inhibition reduces abnormalities in cells from patients with myotonic dystrophy and in a mouse model.
Ketley A, Wojciechowska M, Ghidelli-Disse S, Bamborough P, Ghosh TK, Morato ML, Sedehizadeh S, Malik NA, Tang Z, Powalowska P, Tanner M, Billeter-Clark R, Trueman RC, Geiszler PC, Agostini A, Othman O, Bösche M, Bantscheff M, Rüdiger M, Mossakowska DE, Drewry DH, Zuercher WJ, Thornton CA, Drewes G, Uings I, Hayes CJ, Brook JD. Ketley A, et al. Sci Transl Med. 2020 Apr 29;12(541):eaaz2415. doi: 10.1126/scitranslmed.aaz2415. Sci Transl Med. 2020. PMID: 32350131
Antisense oligonucleotide targeting DMPK in patients with myotonic dystrophy type 1: a multicentre, randomised, dose-escalation, placebo-controlled, phase 1/2a trial.
Thornton CA, Moxley RT 3rd, Eichinger K, Heatwole C, Mignon L, Arnold WD, Ashizawa T, Day JW, Dent G, Tanner MK, Duong T, Greene EP, Herbelin L, Johnson NE, King W, Kissel JT, Leung DG, Lott DJ, Norris DA, Pucillo EM, Schell W, Statland JM, Stinson N, Subramony SH, Xia S, Bishop KM, Bennett CF. Thornton CA, et al. Among authors: tanner mk. Lancet Neurol. 2023 Mar;22(3):218-228. doi: 10.1016/S1474-4422(23)00001-7. Lancet Neurol. 2023. PMID: 36804094 Clinical Trial.
Cumulative donor-specific antibody threshold predicts platelet transfusion response in HLA-alloimmunized patients.
Boothby AB, Tanner MK, Alswied A, Youngs D, Bribiesca Rodriguez J, Bikkani T, Cha N, Gernsheimer T, Gimferrer I, Hess JR, Sokol-Hessner L, Marivada S, Nash MG, Flegel WA, Vassallo RR, Stroncek DF, Tsang HC, Panch SR. Boothby AB, et al. Among authors: tanner mk. Blood Adv. 2024 Sep 10;8(17):4689-4699. doi: 10.1182/bloodadvances.2024014143. Blood Adv. 2024. PMID: 39028936 Free PMC article.
Duration- and sex-dependent neural circuit control of voluntary physical activity.
Tanner MK, Davis JKP, Jaime J, Moya NA, Hohorst AA, Bonar K, Abrams KA, Jamil N, Han R, Hubert TJ, Brown N, Loetz EC, Greenwood BN. Tanner MK, et al. Psychopharmacology (Berl). 2022 Nov;239(11):3697-3709. doi: 10.1007/s00213-022-06243-0. Epub 2022 Oct 4. Psychopharmacology (Berl). 2022. PMID: 36195731 Free PMC article.
35 results