Evans L - Search Results

1

Generation of a double transgenic humanized neonatal Fc receptor (FcRn)/albumin mouse to study the pharmacokinetics of albumin-linked drugs.

Viuff D, Antunes F, Evans L, Cameron J, Dyrnesli H, Thue Ravn B, Stougaard M, Thiam K, Andersen B, Kjærulff S, Howard KA. Viuff D, et al. Among authors: evans l. J Control Release. 2016 Feb 10;223:22-30. doi: 10.1016/j.jconrel.2015.12.019. Epub 2015 Dec 14. J Control Release. 2016. PMID: 26699424

2

Albumin as a versatile platform for drug half-life extension.

Sleep D, Cameron J, Evans LR. Sleep D, et al. Biochim Biophys Acta. 2013 Dec;1830(12):5526-34. doi: 10.1016/j.bbagen.2013.04.023. Epub 2013 Apr 29. Biochim Biophys Acta. 2013. PMID: 23639804 Review.

3

Extending serum half-life of albumin by engineering neonatal Fc receptor (FcRn) binding.

Andersen JT, Dalhus B, Viuff D, Ravn BT, Gunnarsen KS, Plumridge A, Bunting K, Antunes F, Williamson R, Athwal S, Allan E, Evans L, Bjørås M, Kjærulff S, Sleep D, Sandlie I, Cameron J. Andersen JT, et al. Among authors: evans l. J Biol Chem. 2014 May 9;289(19):13492-502. doi: 10.1074/jbc.M114.549832. Epub 2014 Mar 20. J Biol Chem. 2014. PMID: 24652290 Free PMC article.

4

Single-chain variable fragment albumin fusions bind the neonatal Fc receptor (FcRn) in a species-dependent manner: implications for in vivo half-life evaluation of albumin fusion therapeutics.

Andersen JT, Cameron J, Plumridge A, Evans L, Sleep D, Sandlie I. Andersen JT, et al. Among authors: evans l. J Biol Chem. 2013 Aug 16;288(33):24277-85. doi: 10.1074/jbc.M113.463000. Epub 2013 Jul 1. J Biol Chem. 2013. PMID: 23818524 Free PMC article.

5

Structure-based mutagenesis reveals the albumin-binding site of the neonatal Fc receptor.

Andersen JT, Dalhus B, Cameron J, Daba MB, Plumridge A, Evans L, Brennan SO, Gunnarsen KS, Bjørås M, Sleep D, Sandlie I. Andersen JT, et al. Among authors: evans l. Nat Commun. 2012 Jan 3;3:610. doi: 10.1038/ncomms1607. Nat Commun. 2012. PMID: 22215085 Free PMC article.

6

The production, characterisation and enhanced pharmacokinetics of scFv-albumin fusions expressed in Saccharomyces cerevisiae.

Evans L, Hughes M, Waters J, Cameron J, Dodsworth N, Tooth D, Greenfield A, Sleep D. Evans L, et al. Protein Expr Purif. 2010 Oct;73(2):113-24. doi: 10.1016/j.pep.2010.05.009. Epub 2010 May 27. Protein Expr Purif. 2010. PMID: 20546898

7

Modulation of chaperone gene expression in mutagenized Saccharomyces cerevisiae strains developed for recombinant human albumin production results in increased production of multiple heterologous proteins.

Payne T, Finnis C, Evans LR, Mead DJ, Avery SV, Archer DB, Sleep D. Payne T, et al. Among authors: evans lr. Appl Environ Microbiol. 2008 Dec;74(24):7759-66. doi: 10.1128/AEM.01178-08. Epub 2008 Oct 17. Appl Environ Microbiol. 2008. PMID: 18931293 Free PMC article.

8

Yeast 2 microm plasmid copy number is elevated by a mutation in the nuclear gene UBC4.

Sleep D, Finnis C, Turner A, Evans L. Sleep D, et al. Among authors: evans l. Yeast. 2001 Mar 30;18(5):403-21. doi: 10.1002/yea.679. Yeast. 2001. PMID: 11255249

9

Trial of alginates in throat symptoms: protocol for a pragmatic, multicentre, placebo controlled, double blind, parallel, randomised controlled trial of liquid alginate (Gaviscon Advance) for the treatment of persistent throat symptoms.

Morton M, Smith H, Fouweather T, Joyce R, Evans L, Thompson J, Wood R, Teare D, Maier R, McGlashan J, Hamilton D, O'Hara J. Morton M, et al. Among authors: evans l. BMJ Open. 2025 Jan 8;15(1):e087729. doi: 10.1136/bmjopen-2024-087729. BMJ Open. 2025. PMID: 39779273 Free article.

10

Combining In Vivo Two-Photon and Laser Speckle Microscopy With the Ex Vivo Capillary-Parenchymal Arteriole Preparation as a Novel Approach to Study Neurovascular Coupling.

Evans LE, Gray AL, Walsh KR, Danby TGE, Pritchard HAT, Allan SM, Gurney AM, Greenstein AS, Schiessl I. Evans LE, et al. Microcirculation. 2025 Jan;32(1):e70001. doi: 10.1111/micc.70001. Microcirculation. 2025. PMID: 39777814 Free PMC article.

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