Poštová-Slavětínská L - Search Results

1

Synthesis and biological properties of prodrugs of (S)-3-(adenin-9-yl)-2-(phosphonomethoxy)propanoic acid.

Kaiser MM, Poštová-Slavětínská L, Dračínský M, Lee YJ, Tian Y, Janeba Z. Kaiser MM, et al. Eur J Med Chem. 2016 Jan 27;108:374-380. doi: 10.1016/j.ejmech.2015.12.009. Epub 2015 Dec 12. Eur J Med Chem. 2016. PMID: 26706348

2

Rational design of urea-based glutamate carboxypeptidase II (GCPII) inhibitors as versatile tools for specific drug targeting and delivery.

Tykvart J, Schimer J, Bařinková J, Pachl P, Poštová-Slavětínská L, Majer P, Konvalinka J, Šácha P. Tykvart J, et al. Bioorg Med Chem. 2014 Aug 1;22(15):4099-108. doi: 10.1016/j.bmc.2014.05.061. Epub 2014 Jun 5. Bioorg Med Chem. 2014. PMID: 24954515

3

Synthesis, conformational studies, and biological properties of phosphonomethoxyethyl derivatives of nucleobases with a locked conformation via a pyrrolidine ring.

Pohl R, Poštová Slavětínská L, Eng WS, Keough DT, Guddat LW, Rejman D. Pohl R, et al. Org Biomol Chem. 2015 Apr 28;13(16):4693-705. doi: 10.1039/c5ob00097a. Org Biomol Chem. 2015. PMID: 25798893

4

Synthesis and Evaluation of Novel Acyclic Nucleoside Phosphonates as Inhibitors of Plasmodium falciparum and Human 6-Oxopurine Phosphoribosyltransferases.

Kaiser MM, Hocková D, Wang TH, Dračínský M, Poštová-Slavětínská L, Procházková E, Edstein MD, Chavchich M, Keough DT, Guddat LW, Janeba Z. Kaiser MM, et al. ChemMedChem. 2015 Oct;10(10):1707-23. doi: 10.1002/cmdc.201500322. Epub 2015 Aug 25. ChemMedChem. 2015. PMID: 26368337

5

Synthesis and biological profiling of 6- or 7-(het)aryl-7-deazapurine 4'-C-methylribonucleosides.

Nauš P, Caletková O, Perlíková P, Poštová Slavětínská L, Tloušťová E, Hodek J, Weber J, Džubák P, Hajdúch M, Hocek M. Nauš P, et al. Bioorg Med Chem. 2015 Dec 1;23(23):7422-38. doi: 10.1016/j.bmc.2015.10.040. Epub 2015 Oct 31. Bioorg Med Chem. 2015. PMID: 26558518

6

Acyclic Nucleoside Phosphonates Containing 9-Deazahypoxanthine and a Five-Membered Heterocycle as Selective Inhibitors of Plasmodial 6-Oxopurine Phosphoribosyltransferases.

Kaiser MM, Baszczyňski O, Hocková D, Poštová-Slavětínská L, Dračínský M, Keough DT, Guddat LW, Janeba Z. Kaiser MM, et al. ChemMedChem. 2017 Jul 20;12(14):1133-1141. doi: 10.1002/cmdc.201700293. Epub 2017 Jul 11. ChemMedChem. 2017. PMID: 28628279

7

Synthesis and Cytotoxic and Antiviral Profiling of Pyrrolo- and Furo-Fused 7-Deazapurine Ribonucleosides.

Tokarenko A, Lišková B, Smoleń S, Táborská N, Tichý M, Gurská S, Perlíková P, Frydrych I, Tloušt'ová E, Znojek P, Mertlíková-Kaiserová H, Poštová Slavětínská L, Pohl R, Klepetářová B, Khalid NU, Wenren Y, Laposa RR, Džubák P, Hajdúch M, Hocek M. Tokarenko A, et al. J Med Chem. 2018 Oct 25;61(20):9347-9359. doi: 10.1021/acs.jmedchem.8b01258. Epub 2018 Oct 16. J Med Chem. 2018. PMID: 30281308 Free article.

8

Efficient Synthesis of α-Branched Purine-Based Acyclic Nucleosides: Scopes and Limitations of the Method.

Frydrych J, Poštová Slavětínská L, Dračínský M, Janeba Z. Frydrych J, et al. Among authors: postova slavetinska l. Molecules. 2020 Sep 19;25(18):4307. doi: 10.3390/molecules25184307. Molecules. 2020. PMID: 32961820 Free PMC article.

9

1,2,4-Thiadiazole acyclic nucleoside phosphonates as inhibitors of cysteine dependent enzymes cathepsin K and GSK-3β.

Pomeislová A, Otmar M, Rubešová P, Benýšek J, Matoušová M, Mertlíková-Kaiserová H, Pohl R, Poštová Slavětínská L, Pomeisl K, Krečmerová M. Pomeislová A, et al. Among authors: postova slavetinska l. Bioorg Med Chem. 2021 Feb 15;32:115998. doi: 10.1016/j.bmc.2021.115998. Epub 2021 Jan 6. Bioorg Med Chem. 2021. PMID: 33440320

10

Protected 2'-deoxyribonucleoside triphosphate building blocks for the photocaging of epigenetic 5-(hydroxymethyl)cytosine in DNA.

Boháčová S, Vaníková Z, Poštová Slavětínská L, Hocek M. Boháčová S, et al. Org Biomol Chem. 2018 Aug 1;16(30):5427-5432. doi: 10.1039/c8ob01106k. Org Biomol Chem. 2018. PMID: 29905748

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