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Page 1
Identification and validation of biomarkers for autism spectrum disorders.
Loth E, Spooren W, Ham LM, Isaac MB, Auriche-Benichou C, Banaschewski T, Baron-Cohen S, Broich K, Bölte S, Bourgeron T, Charman T, Collier D, de Andres-Trelles F, Durston S, Ecker C, Elferink A, Haberkamp M, Hemmings R, Johnson MH, Jones EJ, Khwaja OS, Lenton S, Mason L, Mantua V, Meyer-Lindenberg A, Lombardo MV, O'Dwyer L, Okamoto K, Pandina GJ, Pani L, Persico AM, Simonoff E, Tauscher-Wisniewski S, Llinares-Garcia J, Vamvakas S, Williams S, Buitelaar JK, Murphy DG. Loth E, et al. Among authors: broich k. Nat Rev Drug Discov. 2016 Jan;15(1):70-3. doi: 10.1038/nrd.2015.7. Nat Rev Drug Discov. 2016. PMID: 26718285 No abstract available.
DSM-5 and clinical trials in psychiatry: challenges to come?
Butlen-Ducuing F, Haas M, Pani L, van Zwieten-Boot B, Broich K. Butlen-Ducuing F, et al. Among authors: broich k. Nat Rev Drug Discov. 2012 Aug;11(8):583-4. doi: 10.1038/nrd3811. Nat Rev Drug Discov. 2012. PMID: 22850770
Taking stock: A multistakeholder perspective on improving the delivery of care and the development of treatments for Alzheimer's disease.
Bradley P, Akehurst R, Ballard C, Banerjee S, Blennow K, Bremner J, Broich K, Cummings J, Dening K, Dubois B, Klipper W, Leibman C, Mantua V, Molinuevo JL, Morgan S, Muscolo LA, Nicolas F, Pani L, Robinson L, Siviero P, van Dam J, Van Emelen J, Wimo A, Wortmann M, Goh L. Bradley P, et al. Among authors: broich k. Alzheimers Dement. 2015 Apr;11(4):455-61. doi: 10.1016/j.jalz.2014.01.007. Epub 2014 Apr 21. Alzheimers Dement. 2015. PMID: 24751826 Free article.
Biomarkers for Alzheimer's disease: academic, industry and regulatory perspectives.
Hampel H, Frank R, Broich K, Teipel SJ, Katz RG, Hardy J, Herholz K, Bokde AL, Jessen F, Hoessler YC, Sanhai WR, Zetterberg H, Woodcock J, Blennow K. Hampel H, et al. Among authors: broich k. Nat Rev Drug Discov. 2010 Jul;9(7):560-74. doi: 10.1038/nrd3115. Nat Rev Drug Discov. 2010. PMID: 20592748 Review.
Blood-based systems biology biomarkers for next-generation clinical trials in Alzheimer's disease
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Hampel H, Vergallo A, Afshar M, Akman-Anderson L, Arenas J, Benda N, Batrla R, Broich K, Caraci F, Cuello AC, Emanuele E, Haberkamp M, Kiddle SJ, Lucía A, Mapstone M, Verdooner SR, Woodcock J, Lista S. Hampel H, et al. Among authors: broich k. Dialogues Clin Neurosci. 2019;21(2):177-191. doi: 10.31887/DCNS.2019.21.2/hhampel. Dialogues Clin Neurosci. 2019. PMID: 31636492 Free PMC article.
Precision pharmacology for Alzheimer's disease.
Hampel H, Vergallo A, Aguilar LF, Benda N, Broich K, Cuello AC, Cummings J, Dubois B, Federoff HJ, Fiandaca M, Genthon R, Haberkamp M, Karran E, Mapstone M, Perry G, Schneider LS, Welikovitch LA, Woodcock J, Baldacci F, Lista S; Alzheimer Precision Medicine Initiative (APMI). Hampel H, et al. Among authors: broich k. Pharmacol Res. 2018 Apr;130:331-365. doi: 10.1016/j.phrs.2018.02.014. Epub 2018 Feb 16. Pharmacol Res. 2018. PMID: 29458203 Free PMC article. Review.
Future avenues for Alzheimer's disease detection and therapy: liquid biopsy, intracellular signaling modulation, systems pharmacology drug discovery.
Hampel H, Vergallo A, Caraci F, Cuello AC, Lemercier P, Vellas B, Giudici KV, Baldacci F, Hänisch B, Haberkamp M, Broich K, Nisticò R, Emanuele E, Llavero F, Zugaza JL, Lucía A, Giacobini E, Lista S; Alzheimer Precision Medicine Initiative. Hampel H, et al. Among authors: broich k. Neuropharmacology. 2021 Mar 1;185:108081. doi: 10.1016/j.neuropharm.2020.108081. Epub 2020 May 11. Neuropharmacology. 2021. PMID: 32407924 Review.
152 results