Akkari L - Search Results

1

High-dose methotrexate-based chemotherapy as treatment for histiocytic sarcoma of the central nervous system.

Curry RC, Faivre G, Akkari L, Joyce JA, Lin O, Rosenblum M, Diamond EL, Fisher R, Omuro A. Curry RC, et al. Among authors: akkari l. Leuk Lymphoma. 2016 Aug;57(8):1961-4. doi: 10.3109/10428194.2015.1120867. Epub 2016 Jan 4. Leuk Lymphoma. 2016. PMID: 26727454 No abstract available.

2

The tumor microenvironment underlies acquired resistance to CSF-1R inhibition in gliomas.

Quail DF, Bowman RL, Akkari L, Quick ML, Schuhmacher AJ, Huse JT, Holland EC, Sutton JC, Joyce JA. Quail DF, et al. Among authors: akkari l. Science. 2016 May 20;352(6288):aad3018. doi: 10.1126/science.aad3018. Science. 2016. PMID: 27199435 Free PMC article.

3

Microenvironmental InterFereNce of metabolism regulates chemosensitivity.

Akkari L, Joyce JA. Akkari L, et al. Cell Res. 2016 Aug;26(8):867-8. doi: 10.1038/cr.2016.82. Epub 2016 Jun 28. Cell Res. 2016. PMID: 27349476 Free PMC article.

4

mTOR regulates phagosome and entotic vacuole fission.

Krajcovic M, Krishna S, Akkari L, Joyce JA, Overholtzer M. Krajcovic M, et al. Among authors: akkari l. Mol Biol Cell. 2013 Dec;24(23):3736-45. doi: 10.1091/mbc.E13-07-0408. Epub 2013 Oct 2. Mol Biol Cell. 2013. PMID: 24088573 Free PMC article.

5

Emergence of spatial structure in the tumor microenvironment due to the Warburg effect.

Carmona-Fontaine C, Bucci V, Akkari L, Deforet M, Joyce JA, Xavier JB. Carmona-Fontaine C, et al. Among authors: akkari l. Proc Natl Acad Sci U S A. 2013 Nov 26;110(48):19402-7. doi: 10.1073/pnas.1311939110. Epub 2013 Nov 11. Proc Natl Acad Sci U S A. 2013. PMID: 24218566 Free PMC article.

6

Combined deletion of cathepsin protease family members reveals compensatory mechanisms in cancer.

Akkari L, Gocheva V, Quick ML, Kester JC, Spencer AK, Garfall AL, Bowman RL, Joyce JA. Akkari L, et al. Genes Dev. 2016 Jan 15;30(2):220-32. doi: 10.1101/gad.270439.115. Genes Dev. 2016. PMID: 26773004 Free PMC article.

7

Metabolic origins of spatial organization in the tumor microenvironment.

Carmona-Fontaine C, Deforet M, Akkari L, Thompson CB, Joyce JA, Xavier JB. Carmona-Fontaine C, et al. Among authors: akkari l. Proc Natl Acad Sci U S A. 2017 Mar 14;114(11):2934-2939. doi: 10.1073/pnas.1700600114. Epub 2017 Feb 28. Proc Natl Acad Sci U S A. 2017. PMID: 28246332 Free PMC article.

8

Inhibition of colony stimulating factor-1 receptor abrogates microenvironment-mediated therapeutic resistance in gliomas.

Yan D, Kowal J, Akkari L, Schuhmacher AJ, Huse JT, West BL, Joyce JA. Yan D, et al. Among authors: akkari l. Oncogene. 2017 Oct 26;36(43):6049-6058. doi: 10.1038/onc.2017.261. Epub 2017 Jul 31. Oncogene. 2017. PMID: 28759044 Free PMC article.

9

Distinct functions of macrophage-derived and cancer cell-derived cathepsin Z combine to promote tumor malignancy via interactions with the extracellular matrix.

Akkari L, Gocheva V, Kester JC, Hunter KE, Quick ML, Sevenich L, Wang HW, Peters C, Tang LH, Klimstra DS, Reinheckel T, Joyce JA. Akkari L, et al. Genes Dev. 2014 Oct 1;28(19):2134-50. doi: 10.1101/gad.249599.114. Genes Dev. 2014. PMID: 25274726 Free PMC article.

10

TAILS N-Terminomics and Proteomics Show Protein Degradation Dominates over Proteolytic Processing by Cathepsins in Pancreatic Tumors.

Prudova A, Gocheva V, Auf dem Keller U, Eckhard U, Olson OC, Akkari L, Butler GS, Fortelny N, Lange PF, Mark JC, Joyce JA, Overall CM. Prudova A, et al. Among authors: akkari l. Cell Rep. 2016 Aug 9;16(6):1762-1773. doi: 10.1016/j.celrep.2016.06.086. Epub 2016 Jul 28. Cell Rep. 2016. PMID: 27477282 Free article.

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