Chung MC - Search Results

1

The Prodrug Approach: A Successful Tool for Improving Drug Solubility.

Jornada DH, dos Santos Fernandes GF, Chiba DE, de Melo TR, dos Santos JL, Chung MC. Jornada DH, et al. Among authors: chung mc. Molecules. 2015 Dec 29;21(1):42. doi: 10.3390/molecules21010042. Molecules. 2015. PMID: 26729077 Free PMC article. Review.

2

A prodrug approach to improve the physico-chemical properties and decrease the genotoxicity of nitro compounds.

Chung MC, Bosquesi PL, dos Santos JL. Chung MC, et al. Curr Pharm Des. 2011;17(32):3515-26. doi: 10.2174/138161211798194512. Curr Pharm Des. 2011. PMID: 22074424 Review.

3

Synthesis, ex vivo and in vitro hydrolysis study of an indoline derivative designed as an anti-inflammatory with reduced gastric ulceration properties.

Chung MC, dos Santos JL, Oliveira EV, Blau L, Menegon RF, Peccinini RG. Chung MC, et al. Molecules. 2009 Aug 26;14(9):3187-97. doi: 10.3390/molecules14093187. Molecules. 2009. PMID: 19783917 Free PMC article.

4

Synthesis, characterization and pharmacological evaluation of 1-(2-chloro-6-fluorophenyl)-5-methylindolin-2-one: a new anti-inflammatory compound with reduced gastric ulceration properties.

dos Santos JL, Chelucci R, Chiquetto R, Chung MC, Campos ML, Peccinini RG. dos Santos JL, et al. Among authors: chung mc. Molecules. 2010 Nov 8;15(11):8039-47. doi: 10.3390/molecules15118039. Molecules. 2010. PMID: 21060305 Free PMC article.

5

Assessment of the in vivo genotoxicity of new lead compounds to treat sickle cell disease.

Dos Santos JL, Longhin Bosquesi P, Varanda EA, Moreira Lima L, Chung MC. Dos Santos JL, et al. Among authors: chung mc. Molecules. 2011 Apr 6;16(4):2982-9. doi: 10.3390/molecules16042982. Molecules. 2011. PMID: 21471937 Free PMC article.

6

Antiplatelet and antithrombotic activities of non-steroidal anti-inflammatory drugs containing an N-acyl hydrazone subunit.

Chelucci RC, Dutra LA, Lopes Pires ME, de Melo TR, Bosquesi PL, Chung MC, Dos Santos JL. Chelucci RC, et al. Among authors: chung mc. Molecules. 2014 Feb 17;19(2):2089-99. doi: 10.3390/molecules19022089. Molecules. 2014. PMID: 24549233 Free PMC article.

7

Current advances in drug discovery for Chagas disease.

Scarim CB, Jornada DH, Chelucci RC, de Almeida L, Dos Santos JL, Chung MC. Scarim CB, et al. Among authors: chung mc. Eur J Med Chem. 2018 Jul 15;155:824-838. doi: 10.1016/j.ejmech.2018.06.040. Epub 2018 Jun 20. Eur J Med Chem. 2018. PMID: 30033393 Review.

8

Thiazole, thio and semicarbazone derivatives against tropical infective diseases: Chagas disease, human African trypanosomiasis (HAT), leishmaniasis, and malaria.

Scarim CB, Jornada DH, Machado MGM, Ferreira CMR, Dos Santos JL, Chung MC. Scarim CB, et al. Among authors: chung mc. Eur J Med Chem. 2019 Jan 15;162:378-395. doi: 10.1016/j.ejmech.2018.11.013. Epub 2018 Nov 12. Eur J Med Chem. 2019. PMID: 30453246 Review.

9

Synthesis, antioxidant and photoprotection activities of hybrid derivatives useful to prevent skin cancer.

Reis JS, Corrêa MA, Chung MC, Dos Santos JL. Reis JS, et al. Among authors: chung mc. Bioorg Med Chem. 2014 May 1;22(9):2733-8. doi: 10.1016/j.bmc.2014.03.017. Epub 2014 Mar 19. Bioorg Med Chem. 2014. PMID: 24690528

10

Pharmacological evaluation and preparation of nonsteroidal anti-inflammatory drugs containing an N-acyl hydrazone subunit.

de Melo TR, Chelucci RC, Pires ME, Dutra LA, Barbieri KP, Bosquesi PL, Trossini GH, Chung MC, dos Santos JL. de Melo TR, et al. Among authors: chung mc. Int J Mol Sci. 2014 Apr 4;15(4):5821-37. doi: 10.3390/ijms15045821. Int J Mol Sci. 2014. PMID: 24714090 Free PMC article.

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