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Effects of chronic guanosine treatment on hippocampal damage and cognitive impairment of rats submitted to chronic cerebral hypoperfusion.
Ganzella M, de Oliveira ED, Comassetto DD, Cechetti F, Cereser VH Jr, Moreira JD, Hansel G, Almeida RF, Ramos DB, Figueredo YN, Souza DG, Oses JP, Worm PV, Achaval M, Netto CA, Souza DO. Ganzella M, et al. Neurol Sci. 2012 Oct;33(5):985-97. doi: 10.1007/s10072-011-0872-1. Epub 2011 Dec 14. Neurol Sci. 2012. PMID: 22167652
Intranasal guanosine administration presents a wide therapeutic time window to reduce brain damage induced by permanent ischemia in rats.
Ramos DB, Muller GC, Rocha GB, Dellavia GH, Almeida RF, Pettenuzzo LF, Loureiro SO, Hansel G, Horn ÂC, Souza DO, Ganzella M. Ramos DB, et al. Among authors: ganzella m. Purinergic Signal. 2016 Mar;12(1):149-59. doi: 10.1007/s11302-015-9489-9. Epub 2015 Dec 23. Purinergic Signal. 2016. PMID: 26695181 Free PMC article.
Systemic administration of GMP induces anxiolytic-like behavior in rats.
Almeida RF, Cereser VH Jr, Faraco RB, Böhmer AE, Souza DO, Ganzella M. Almeida RF, et al. Among authors: ganzella m. Pharmacol Biochem Behav. 2010 Sep;96(3):306-11. doi: 10.1016/j.pbb.2010.05.022. Epub 2010 Jun 1. Pharmacol Biochem Behav. 2010. PMID: 20566406 Free article.
Olfactory bulbectomy in mice triggers transient and long-lasting behavioral impairments and biochemical hippocampal disturbances.
Almeida RF, Ganzella M, Machado DG, Loureiro SO, Leffa D, Quincozes-Santos A, Pettenuzzo LF, Duarte MMMF, Duarte T, Souza DO. Almeida RF, et al. Among authors: ganzella m. Prog Neuropsychopharmacol Biol Psychiatry. 2017 Jun 2;76:1-11. doi: 10.1016/j.pnpbp.2017.02.013. Epub 2017 Feb 20. Prog Neuropsychopharmacol Biol Psychiatry. 2017. PMID: 28223107 Free article.
Antidepressant-Like Effects of Chronic Guanosine in the Olfactory Bulbectomy Mouse Model.
Almeida RF, Nonose Y, Ganzella M, Loureiro SO, Rocha A, Machado DG, Bellaver B, Fontella FU, Leffa DT, Pettenuzzo LF, Venturin GT, Greggio S, da Costa JC, Zimmer ER, Elisabetsky E, Souza DO. Almeida RF, et al. Among authors: ganzella m. Front Psychiatry. 2021 Aug 4;12:701408. doi: 10.3389/fpsyt.2021.701408. eCollection 2021. Front Psychiatry. 2021. PMID: 34421682 Free PMC article.
Amnesic effect of GMP depends on its conversion to guanosine.
Saute JA, da Silveira LE, Soares FA, Martini LH, Souza DO, Ganzella M. Saute JA, et al. Among authors: ganzella m. Neurobiol Learn Mem. 2006 May;85(3):206-12. doi: 10.1016/j.nlm.2005.10.006. Epub 2005 Dec 1. Neurobiol Learn Mem. 2006. PMID: 16325434
37 results