Leng S - Search Results

1

Whole exome sequencing identifies novel candidate genes that modify chronic obstructive pulmonary disease susceptibility.

Bruse S, Moreau M, Bromberg Y, Jang JH, Wang N, Ha H, Picchi M, Lin Y, Langley RJ, Qualls C, Klensney-Tait J, Zabner J, Leng S, Mao J, Belinsky SA, Xing J, Nyunoya T. Bruse S, et al. Among authors: leng s. Hum Genomics. 2016 Jan 7;10:1. doi: 10.1186/s40246-015-0058-7. Hum Genomics. 2016. PMID: 26744305 Free PMC article.

2

Double-strand break damage and associated DNA repair genes predispose smokers to gene methylation.

Leng S, Stidley CA, Willink R, Bernauer A, Do K, Picchi MA, Sheng X, Frasco MA, Van Den Berg D, Gilliland FD, Zima C, Crowell RE, Belinsky SA. Leng S, et al. Cancer Res. 2008 Apr 15;68(8):3049-56. doi: 10.1158/0008-5472.CAN-07-6344. Cancer Res. 2008. PMID: 18413776 Free PMC article.

3

Haplotypes of DNMT1 and DNMT3B are associated with mutagen sensitivity induced by benzo[a]pyrene diol epoxide among smokers.

Leng S, Stidley CA, Bernauer AM, Picchi MA, Sheng X, Frasco MA, Van Den Berg D, Gilliland FD, Crowell RE, Belinsky SA. Leng S, et al. Carcinogenesis. 2008 Jul;29(7):1380-5. doi: 10.1093/carcin/bgn121. Epub 2008 May 21. Carcinogenesis. 2008. PMID: 18499700 Free PMC article.

4

Association between common genetic variation in Cockayne syndrome A and B genes and nucleotide excision repair capacity among smokers.

Leng S, Bernauer A, Stidley CA, Picchi MA, Sheng X, Frasco MA, Van Den Berg D, Gilliland FD, Crowell RE, Belinsky SA. Leng S, et al. Cancer Epidemiol Biomarkers Prev. 2008 Aug;17(8):2062-9. doi: 10.1158/1055-9965.EPI-08-0308. Cancer Epidemiol Biomarkers Prev. 2008. PMID: 18708399

5

A SNP in a let-7 microRNA complementary site in the KRAS 3' untranslated region increases non-small cell lung cancer risk.

Chin LJ, Ratner E, Leng S, Zhai R, Nallur S, Babar I, Muller RU, Straka E, Su L, Burki EA, Crowell RE, Patel R, Kulkarni T, Homer R, Zelterman D, Kidd KK, Zhu Y, Christiani DC, Belinsky SA, Slack FJ, Weidhaas JB. Chin LJ, et al. Among authors: leng s. Cancer Res. 2008 Oct 15;68(20):8535-40. doi: 10.1158/0008-5472.CAN-08-2129. Cancer Res. 2008. PMID: 18922928 Free PMC article.

6

Carcinogen-induced gene promoter hypermethylation is mediated by DNMT1 and causal for transformation of immortalized bronchial epithelial cells.

Damiani LA, Yingling CM, Leng S, Romo PE, Nakamura J, Belinsky SA. Damiani LA, et al. Among authors: leng s. Cancer Res. 2008 Nov 1;68(21):9005-14. doi: 10.1158/0008-5472.CAN-08-1276. Cancer Res. 2008. PMID: 18974146

7

Radiation-stimulated epigenetic reprogramming of adaptive-response genes in the lung: an evolutionary gift for mounting adaptive protection against lung cancer.

Scott BR, Belinsky SA, Leng S, Lin Y, Wilder JA, Damiani LA. Scott BR, et al. Among authors: leng s. Dose Response. 2009 Jun 11;7(2):104-31. doi: 10.2203/dose-response.08-016.Scott. Dose Response. 2009. PMID: 19543479 Free PMC article.

8

Multivitamins, folate, and green vegetables protect against gene promoter methylation in the aerodigestive tract of smokers.

Stidley CA, Picchi MA, Leng S, Willink R, Crowell RE, Flores KG, Kang H, Byers T, Gilliland FD, Belinsky SA. Stidley CA, et al. Among authors: leng s. Cancer Res. 2010 Jan 15;70(2):568-74. doi: 10.1158/0008-5472.CAN-09-3410. Epub 2010 Jan 12. Cancer Res. 2010. PMID: 20068159 Free PMC article.

9

The A/G allele of rs16906252 predicts for MGMT methylation and is selectively silenced in premalignant lesions from smokers and in lung adenocarcinomas.

Leng S, Bernauer AM, Hong C, Do KC, Yingling CM, Flores KG, Tessema M, Tellez CS, Willink RP, Burki EA, Picchi MA, Stidley CA, Prados MD, Costello JF, Gilliland FD, Crowell RE, Belinsky SA. Leng S, et al. Clin Cancer Res. 2011 Apr 1;17(7):2014-23. doi: 10.1158/1078-0432.CCR-10-3026. Epub 2011 Feb 25. Clin Cancer Res. 2011. PMID: 21355081 Free PMC article.

10

EMT and stem cell-like properties associated with miR-205 and miR-200 epigenetic silencing are early manifestations during carcinogen-induced transformation of human lung epithelial cells.

Tellez CS, Juri DE, Do K, Bernauer AM, Thomas CL, Damiani LA, Tessema M, Leng S, Belinsky SA. Tellez CS, et al. Among authors: leng s. Cancer Res. 2011 Apr 15;71(8):3087-97. doi: 10.1158/0008-5472.CAN-10-3035. Epub 2011 Mar 1. Cancer Res. 2011. PMID: 21363915 Free PMC article.

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