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Page 1
Synthesis of novel lincomycin derivatives and their in vitro antibacterial activities.
Umemura E, Wakiyama Y, Kumura K, Ueda K, Masaki S, Watanabe T, Yamamoto M, Hirai Y, Fushimi H, Yoshida T, Ajito K. Umemura E, et al. Among authors: watanabe t. J Antibiot (Tokyo). 2013 Mar;66(3):195-8. doi: 10.1038/ja.2012.107. Epub 2012 Dec 12. J Antibiot (Tokyo). 2013. PMID: 23232934 No abstract available.
Synthesis and structure-activity relationships of novel lincomycin derivatives. Part 2. Synthesis of 7(S)-7-deoxy-7-(4-morpholinocarbonylphenylthio)lincomycin and its 3-dimensional analysis with rRNA.
Wakiyama Y, Kumura K, Umemura E, Masaki S, Ueda K, Watanabe T, Yamamoto M, Hirai Y, Ajito K. Wakiyama Y, et al. Among authors: watanabe t. J Antibiot (Tokyo). 2016 Jun;69(6):428-39. doi: 10.1038/ja.2015.125. Epub 2015 Dec 16. J Antibiot (Tokyo). 2016. PMID: 26669751
Synthesis and structure-activity relationships of novel lincomycin derivatives. Part 4: synthesis of novel lincomycin analogs modified at the 6- and 7-positions and their potent antibacterial activities.
Wakiyama Y, Kumura K, Umemura E, Ueda K, Watanabe T, Yamada K, Okutomi T, Ajito K. Wakiyama Y, et al. Among authors: watanabe t. J Antibiot (Tokyo). 2017 Jul;70(8):888-906. doi: 10.1038/ja.2017.54. Epub 2017 May 31. J Antibiot (Tokyo). 2017. PMID: 28559581
Tricyclic pharmacophore-based molecules as novel integrin alpha(v)beta3 antagonists. Part III: synthesis of potent antagonists with alpha(v)beta3/alpha(IIb)beta3 dual activity and improved water solubility.
Ishikawa M, Hiraiwa Y, Kubota D, Tsushima M, Watanabe T, Murakami S, Ouchi S, Ajito K. Ishikawa M, et al. Among authors: watanabe t. Bioorg Med Chem. 2006 Apr 1;14(7):2131-50. doi: 10.1016/j.bmc.2005.10.055. Epub 2005 Nov 22. Bioorg Med Chem. 2006. PMID: 16307881
X-ray crystallographic analysis of IMP-1 metallo-β-lactamase complexed with a 3-aminophthalic acid derivative, structure-based drug design, and synthesis of 3,6-disubstituted phthalic acid derivative inhibitors.
Hiraiwa Y, Saito J, Watanabe T, Yamada M, Morinaka A, Fukushima T, Kudo T. Hiraiwa Y, et al. Among authors: watanabe t. Bioorg Med Chem Lett. 2014 Oct 15;24(20):4891-4. doi: 10.1016/j.bmcl.2014.08.039. Epub 2014 Sep 6. Bioorg Med Chem Lett. 2014. PMID: 25246278
16,214 results
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