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Page 1
A Focused Screen Identifies Antifolates with Activity on Mycobacterium tuberculosis.
Kumar A, Guardia A, Colmenarejo G, Pérez E, Gonzalez RR, Torres P, Calvo D, Gómez RM, Ortega F, Jiménez E, Gabarro RC, Rullás J, Ballell L, Sherman DR. Kumar A, et al. Among authors: gabarro rc. ACS Infect Dis. 2015 Dec 11;1(12):604-14. doi: 10.1021/acsinfecdis.5b00063. Epub 2015 Aug 12. ACS Infect Dis. 2015. PMID: 26771003 Free PMC article.
Case Study of Small Molecules As Antimalarials: 2-Amino-1-phenylethanol (APE) Derivatives.
Chaparro MJ, Vidal J, Angulo-Barturen I, Bueno JM, Burrows J, Cammack N, Castañeda P, Colmenarejo G, Coterón JM, de Las Heras L, Fernández E, Ferrer S, Gabarró R, Gamo FJ, García M, Jiménez-Díaz MB, Lafuente MJ, León ML, Martínez MS, Minick D, Prats S, Puente M, Rueda L, Sandoval E, Santos-Villarejo A, Witty M, Calderón F. Chaparro MJ, et al. ACS Med Chem Lett. 2014 Mar 26;5(6):657-61. doi: 10.1021/ml500015r. eCollection 2014 Jun 12. ACS Med Chem Lett. 2014. PMID: 24944739 Free PMC article.
Bromodomain Factor 5 as a Target for Antileishmanial Drug Discovery.
Russell CN, Carter JL, Borgia JM, Bush J, Calderón F, Gabarró R, Conway SJ, Mottram JC, Wilkinson AJ, Jones NG. Russell CN, et al. ACS Infect Dis. 2023 Nov 10;9(11):2340-2357. doi: 10.1021/acsinfecdis.3c00431. Epub 2023 Oct 31. ACS Infect Dis. 2023. PMID: 37906637 Free PMC article.
Expanding Bromodomain Targeting into Neglected Parasitic Diseases.
Tallant C, Bamborough P, Chung CW, Gamo FJ, Kirkpatrick R, Larminie C, Martín J, Prinjha R, Rioja I, Simola DF, Gabarró R, Calderón F. Tallant C, et al. ACS Infect Dis. 2021 Nov 12;7(11):2953-2958. doi: 10.1021/acsinfecdis.1c00387. Epub 2021 Oct 6. ACS Infect Dis. 2021. PMID: 34612618
Essential Bromodomain TcBDF2 as a Drug Target against Chagas Disease.
Pezza A, Tavernelli LE, Alonso VL, Perdomo V, Gabarro R, Prinjha R, Rodríguez Araya E, Rioja I, Docampo R, Calderón F, Martin J, Serra E. Pezza A, et al. ACS Infect Dis. 2022 May 13;8(5):1062-1074. doi: 10.1021/acsinfecdis.2c00057. Epub 2022 Apr 28. ACS Infect Dis. 2022. PMID: 35482332
Complex Interplay between Sphingolipid and Sterol Metabolism Revealed by Perturbations to the Leishmania Metabolome Caused by Miltefosine.
Armitage EG, Alqaisi AQI, Godzien J, Peña I, Mbekeani AJ, Alonso-Herranz V, López-Gonzálvez Á, Martín J, Gabarro R, Denny PW, Barrett MP, Barbas C. Armitage EG, et al. Antimicrob Agents Chemother. 2018 Apr 26;62(5):e02095-17. doi: 10.1128/AAC.02095-17. Print 2018 May. Antimicrob Agents Chemother. 2018. PMID: 29463533 Free PMC article.
Bromodomain factor 5 is an essential regulator of transcription in Leishmania.
Jones NG, Geoghegan V, Moore G, Carnielli JBT, Newling K, Calderón F, Gabarró R, Martín J, Prinjha RK, Rioja I, Wilkinson AJ, Mottram JC. Jones NG, et al. Nat Commun. 2022 Jul 13;13(1):4071. doi: 10.1038/s41467-022-31742-1. Nat Commun. 2022. PMID: 35831302 Free PMC article.
11 results