Ahring PK - Search Results

1

High and low GABA sensitivity α4β2δ GABAA receptors are expressed in Xenopus laevis oocytes with divergent stoichiometries.

Hartiadi LY, Ahring PK, Chebib M, Absalom NL. Hartiadi LY, et al. Among authors: ahring pk. Biochem Pharmacol. 2016 Mar 1;103:98-108. doi: 10.1016/j.bcp.2015.12.021. Epub 2016 Jan 13. Biochem Pharmacol. 2016. PMID: 26774457

2

GABAA α5 subunit-containing receptors do not contribute to reversal of inflammatory-induced spinal sensitization as indicated by the unique selectivity profile of the GABAA receptor allosteric modulator NS16085.

de Lucas AG, Ahring PK, Larsen JS, Rivera-Arconada I, Lopez-Garcia JA, Mirza NR, Munro G. de Lucas AG, et al. Among authors: ahring pk. Biochem Pharmacol. 2015 Feb 1;93(3):370-9. doi: 10.1016/j.bcp.2014.12.010. Epub 2014 Dec 25. Biochem Pharmacol. 2015. PMID: 25542996

3

Engineered α4β2 nicotinic acetylcholine receptors as models for measuring agonist binding and effect at the orthosteric low-affinity α4-α4 interface.

Ahring PK, Olsen JA, Nielsen EØ, Peters D, Pedersen MH, Rohde LA, Kastrup JS, Shahsavar A, Indurthi DC, Chebib M, Gajhede M, Balle T. Ahring PK, et al. Neuropharmacology. 2015 May;92:135-45. doi: 10.1016/j.neuropharm.2014.12.035. Epub 2015 Jan 13. Neuropharmacology. 2015. PMID: 25595102

4

Acetylcholine-Binding Protein Engineered to Mimic the α4-α4 Binding Pocket in α4β2 Nicotinic Acetylcholine Receptors Reveals Interface Specific Interactions Important for Binding and Activity.

Shahsavar A, Ahring PK, Olsen JA, Krintel C, Kastrup JS, Balle T, Gajhede M. Shahsavar A, et al. Among authors: ahring pk. Mol Pharmacol. 2015 Oct;88(4):697-707. doi: 10.1124/mol.115.098061. Epub 2015 Jul 15. Mol Pharmacol. 2015. PMID: 26180047

5

Delineation of the functional properties and the mechanism of action of TMPPAA, an allosteric agonist and positive allosteric modulator of 5-HT3 receptors.

Gasiorek A, Trattnig SM, Ahring PK, Kristiansen U, Frølund B, Frederiksen K, Jensen AA. Gasiorek A, et al. Among authors: ahring pk. Biochem Pharmacol. 2016 Jun 15;110-111:92-108. doi: 10.1016/j.bcp.2016.04.004. Epub 2016 Apr 13. Biochem Pharmacol. 2016. PMID: 27086281

6

A pharmacological assessment of agonists and modulators at α4β2γ2 and α4β2δ GABAA receptors: The challenge in comparing apples with oranges.

Ahring PK, Bang LH, Jensen ML, Strøbæk D, Hartiadi LY, Chebib M, Absalom N. Ahring PK, et al. Pharmacol Res. 2016 Sep;111:563-576. doi: 10.1016/j.phrs.2016.05.014. Epub 2016 May 10. Pharmacol Res. 2016. PMID: 27178730

7

A pharmacological characterization of GABA, THIP and DS2 at binary α4β3 and β3δ receptors: GABA activates β3δ receptors via the β3(+)δ(-) interface.

Lee HJ, Absalom NL, Hanrahan JR, van Nieuwenhuijzen P, Ahring PK, Chebib M. Lee HJ, et al. Among authors: ahring pk. Brain Res. 2016 Aug 1;1644:222-30. doi: 10.1016/j.brainres.2016.05.019. Epub 2016 May 12. Brain Res. 2016. PMID: 27181518

8

Zolpidem is a potent stoichiometry-selective modulator of α1β3 GABAA receptors: evidence of a novel benzodiazepine site in the α1-α1 interface.

Che Has AT, Absalom N, van Nieuwenhuijzen PS, Clarkson AN, Ahring PK, Chebib M. Che Has AT, et al. Among authors: ahring pk. Sci Rep. 2016 Jun 27;6:28674. doi: 10.1038/srep28674. Sci Rep. 2016. PMID: 27346730 Free PMC article.

9

Ligand Binding at the 4-4 Agonist-Binding Site of the 42 nAChR Triggers Receptor Activation through a Pre-Activated Conformational State.

Indurthi DC, Lewis TM, Ahring PK, Balle T, Chebib M, Absalom NL. Indurthi DC, et al. Among authors: ahring pk. PLoS One. 2016 Aug 23;11(8):e0161154. doi: 10.1371/journal.pone.0161154. eCollection 2016. PLoS One. 2016. PMID: 27552221 Free PMC article.

10

The flavonoid, 2'-methoxy-6-methylflavone, affords neuroprotection following focal cerebral ischaemia.

Clarkson AN, Boothman-Burrell L, Dósa Z, Nagaraja RY, Jin L, Parker K, van Nieuwenhuijzen PS, Neumann S, Gowing EK, Gavande N, Ahring PK, Holm MM, Hanrahan JR, Nicolazzo JA, Jensen K, Chebib M. Clarkson AN, et al. Among authors: ahring pk. J Cereb Blood Flow Metab. 2019 Jul;39(7):1266-1282. doi: 10.1177/0271678X18755628. Epub 2018 Jan 29. J Cereb Blood Flow Metab. 2019. PMID: 29376464 Free PMC article.

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